Response to ‘The start of another infection prevention learning curve: reducing healthcare-associated Gram-negative bloodstream infections’

2018 ◽  
Vol 99 (4) ◽  
pp. 432-434 ◽  
Author(s):  
A. Joseph ◽  
V. Weston ◽  
T. Boswell
2010 ◽  
Vol 31 (S1) ◽  
pp. S27-S31 ◽  
Author(s):  
Kristina A. Bryant ◽  
Danielle M. Zerr ◽  
W. Charles Huskins ◽  
Aaron M. Milstone

Central line–associated bloodstream infections cause morbidity and mortality in children. We explore the evidence for prevention of central line–associated bloodstream infections in children, assess current practices, and propose research topics to improve prevention strategies.


2019 ◽  
Vol 132 (1) ◽  
pp. 5-15
Author(s):  
Eleanor Mitchell ◽  
Mark S Pearce ◽  
Anthony Roberts

Abstract Introduction and background Incidence of gram-negative bloodstream infections (GNBSIs) and sepsis are rising in the UK. Healthcare-associated risk factors have been identified that increase the risk of infection and associated mortality. Current research is focused on identifying high-risk patients and improving the methods used for surveillance. Sources of data Comprehensive literature search of the topic area using PubMed (Medline). Government, professional and societal publications were also reviewed. Areas of agreement A range of healthcare-associated risk factors independently associate with the risk of GNBSIs and sepsis. Areas of controversy There are calls to move away from using simple comorbidity scores to predict the risk of sepsis-associated mortality, instead more advanced multimorbidity models should be considered. Growing points and areas for developing research Advanced risk models should be created and evaluated for their ability to predict sepsis-associated mortality. Investigations into the accuracy of NEWS2 to predict sepsis-associated mortality are required.


2018 ◽  
Vol 98 (3) ◽  
pp. 225-227 ◽  
Author(s):  
J. Gray ◽  
B. Oppenheim ◽  
N. Mahida

2019 ◽  
Vol 101 (2) ◽  
pp. 134-141 ◽  
Author(s):  
F.S. Rodrigues ◽  
F.A. Clemente de Luca ◽  
A. Ribeiro da Cunha ◽  
C.M.C.B. Fortaleza

2014 ◽  
Vol 35 (1) ◽  
pp. 85-88 ◽  
Author(s):  
Carlos Magno Castelo Branco Fortaleza ◽  
Silvia Maria Caldeira ◽  
Rayana Gonçalves Moreira ◽  
Renata Tamie Akazawa ◽  
José Eduardo Corrente ◽  
...  

We studied the influence of weather on the etiology of healthcare-associated bloodstream infections in a hospital in Brazil during the years 2005–2010. Monthly average temperatures were positively associated with higher incidence of gram-negative bacilli as a whole, Acinetobacter baumannii, and Enterobacter species. The same groups presented seasonal behavior in stochastic models.


2016 ◽  
Vol 94 (4) ◽  
pp. 381-385 ◽  
Author(s):  
Ö. Ergönül ◽  
M. Aydin ◽  
A. Azap ◽  
S. Başaran ◽  
S. Tekin ◽  
...  

Author(s):  
Sarah R. MacEwan ◽  
Eliza W. Beal ◽  
Alice A. Gaughan ◽  
Cynthia Sieck ◽  
Ann Scheck McAlearney

Abstract Objective: Device-related healthcare-associated infections (HAIs), such as catheter-associated urinary tract infections (CAUTIs) and central-line–associated bloodstream infections (CLABSIs), are largely preventable. However, there is little evidence of standardized approaches to educate patients about how they can help prevent these infections. We examined the perspectives of hospital leaders and staff about patient education for CAUTI and CLABSI prevention to understand the challenges to patient education and the opportunities for improvement. Methods: In total, 471 interviews were conducted with key informants across 18 hospitals. Interviews were analyzed deductively and inductively to identify themes around the topic of patient education for infection prevention. Results: Participants identified patient education topics specific to CAUTI and CLABSI prevention, including the risks of indwelling urinary catheters and central lines, the necessity of hand hygiene, the importance of maintenance care, and the support to speak up. Challenges, such as lack of standardized education, and opportunities, such as involvement of patient and family advisory groups, were also identified regarding patient education for CAUTI and CLABSI prevention. Conclusions: Hospital leaders and staff identified patient education topics, and ways to deliver this information, that were important in the prevention of CAUTIs and CLABSIs. By identifying both challenges and opportunities related to patient education, our results provide guidance on how patient education for infection prevention can be further improved. Future work should evaluate the implementation of standardized approaches to patient education to better understand the potential impact of these strategies on the reduction of HAIs.


2019 ◽  
Vol 48 (6) ◽  
pp. 1768-1782 ◽  
Author(s):  
Jake C Valentine ◽  
Lisa Hall ◽  
Karin M Verspoor ◽  
Leon J Worth

Abstract Background Immunocompromised patients are at increased risk of acquiring healthcare-associated infections (HAIs) and often require specialized models of care. Surveillance of HAIs is essential for effective infection-prevention programmes. However, little is known regarding standardized or specific surveillance methods currently employed for high-risk hospitalized patients. Methods A systematic review adopting a narrative synthesis approach of published material between 1 January 2000 and 31 March 2018 was conducted. Publications describing the application of traditional and/or electronic surveillance of HAIs in immunocompromised patient settings were identified from the Ovid MEDLINE®, Ovid Embase® and Elsevier Scopus® search engines [PROSPERO international prospective register of systematic reviews (registration ID: CRD42018093651)]. Results In total, 2708 studies were screened, of whom 17 fulfilled inclusion criteria. Inpatients diagnosed with haematological malignancies were the most-represented immunosuppressed population. The majority of studies described manual HAI surveillance utilizing internationally accepted definitions for infection. Chart review of diagnostic and pathology reports was most commonly employed for case ascertainment. Data linkage of disparate datasets was performed in two studies. The most frequently monitored infections were bloodstream infections and invasive fungal disease. No surveillance programmes applied risk adjustment for reporting surveillance outcomes. Conclusions Targeted, tailored monitoring of HAIs in high-risk immunocompromised settings is infrequently reported in current hospital surveillance programmes. Standardized surveillance frameworks, including risk adjustment and timely data dissemination, are required to adequately support infection-prevention programmes in these populations.


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