Colostomy-Free Bowel Injury Repair.

2021 ◽  
Vol 28 (11) ◽  
pp. S56
Author(s):  
M Andou ◽  
K Kanno ◽  
S Sakate ◽  
M Sawada ◽  
S Yanai ◽  
...  
Keyword(s):  
Bowel Injury ◽  
Injury Repair

scholarly journals Damage control surgical management of combined small and large bowel injuries in penetrating trauma: Are ostomies still pertinent?

2021 ◽  
Vol 52 (2) ◽  
pp. e4114425
Author(s):  
Carlos Alberto Ordoñez ◽  
Michael Parra ◽  
Yaset Caicedo ◽  
Natalia Padilla ◽  
Edison Angamarca ◽  
...  
Keyword(s):  
Surgical Management ◽  
Large Bowel ◽  
Damage Control ◽  
Primary Anastomosis ◽  
Penetrating Trauma ◽  
Damage Control Surgery ◽  
Bowel Injury ◽  
Penetrating Injuries ◽  
Hollow Viscus ◽  
Injury Repair

Hollow viscus injuries represent a significant portion of overall lesions sustained during penetrating trauma. Currently, isolated small or large bowel injuries are commonly managed via primary anastomosis in patients undergoing definitive laparotomy or deferred anastomosis in patients requiring damage control surgery. The traditional surgical dogma of ostomy has proven to be unnecessary and, in many instances, actually increases morbidity. The aim of this article is to delineate the experience obtained in the management of combined hollow viscus injuries of patients suffering from penetrating trauma. We sought out to determine if primary and/or deferred bowel injury repair via anastomosis is the preferred surgical course in patients suffering from combined small and large bowel penetrating injuries. Our experience shows that more than 90% of all combined penetrating bowel injuries can be managed via primary or deferred anastomosis, even in the most severe cases requiring the application of damage control principles. Applying this strategy, the overall need for an ostomy (primary or deferred) could be reduced to less than 10%.

Adult HNF1beta+ cells give rise to oval cells but do not significantly contribute to normal homeostasis or injury repair of hepatocytes in mice

2013 ◽  
Vol 51 (01) ◽  
Author(s):  
S Jörs ◽  
P Jeliazkova ◽  
M Ringelhan ◽  
J Ferrer ◽  
RM Schmid ◽  
...  
Keyword(s):  
Oval Cells ◽  
Injury Repair

Surgical Complications Requiring Intervention in Open versus Minimally Invasive Radical Prostatectomy

2021 ◽  
pp. 1-5
Author(s):  
Lorine Haeuser ◽  
Stephen W. Reese ◽  
Marco Paciotti ◽  
Joachim Noldus ◽  
Ethan Y. Brovman ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Minimally Invasive ◽  
Surgical Approach ◽  
Large Bowel ◽  
Bowel Injury ◽  
Improvement Program ◽  
Significant Difference ◽  
American College Of Surgeons ◽  
Vascular Structures ◽  
Open Versus

<b><i>Introduction:</i></b> Injuries to surrounding structures during radical prostatectomy (RP) are rare but serious complications. However, it remains unknown if injuries to intestines, rectum, or vascular structures occur at different rates depending on the surgical approach. <b><i>Methods:</i></b> We compared the frequency of these outcomes in open RP (ORP) and minimally invasive RP (MIS-RP) using the national American College of Surgeons National Surgical Quality Improvement Program database (2012–2017). Along with important metrics of clinical and surgical outcomes, patients were identified as undergoing surgical repair of small or large bowel, vascular structures, or hernias based on Current Procedural Terminology codes. <b><i>Results:</i></b> In our propensity matched analysis, a total of 13,044 patients were captured. Bowel injury occurred more frequently in ORP than in MIS-RP (0.89 vs. 0.26%, <i>p</i> &#x3c; 0.01). By intestinal segment, rectal and large bowel injuries were more common in ORP than MIS-RP (0.41 vs. 0.11% and 0.31 vs. 0.05%, both <i>p</i> &#x3c; 0.01). However, there was no statistically significant difference between the groups for small bowel injury (0.17 vs. 0.11%, <i>p</i> = 0.39). Vascular injury was more common in MIS-RP (0.18 vs. 0.08%, <i>p</i> = 0.08). Hernias requiring repair were only identified in the MIS-RP group (0.12%). <b><i>Conclusion:</i></b> When considering surgical approach, rectal and large bowel injuries were more common in ORP, while vascular injuries and hernia repair were more common in MIS-RP. Our findings can be used in counseling patients and identifying risk factors and strategies to reduce these complications.

scholarly journals Bilateral Nephrectomy in Patients with Autosomal Dominant Polycystic Kidney Disease and End-Stage Chronic Renal Failure

Nephron ◽  
2021 ◽  
pp. 1-7
Author(s):  
Alexander E. Lubennikov ◽  
Nicolay V. Petrovskii ◽  
German E. Krupinov ◽  
Evgeniy M. Shilov ◽  
Roman N. Trushkin ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Large Bowel ◽  
Elective Surgery ◽  
Length Of Hospital Stay ◽  
Bowel Injury ◽  
Polycystic Kidney ◽  
Group I ◽  
Group Ii ◽  
Autosomal Dominant Polycystic Kidney ◽  
End Stage

<b><i>Background:</i></b> In patients with autosomal dominant polycystic kidney disease (ADPKD) and end-stage kidney disease, bilateral nephrectomy (BN) is currently performed predominantly via the laparoscopic approach. We analysed the results of BN depending on the approach and preoperative and perioperative factors. <b><i>Patients and Methods:</i></b> This was a single-centre retrospective study carried out from April 2010 to March 2020, including a total of 142 patients presenting with ADPKD who were treated by BN. Of these, 108 patients meeting the inclusion criteria were selected to analyse the results. We compared therapeutic outcomes depending on the surgical approach (laparotomy or laparoscopy) and the type of the operation (emergent or elective). <b><i>Results:</i></b> Of the 108 eligible patients, 36 (group I) underwent laparoscopic BN and the remaining 72 patients (group II) were subjected to midline laparotomy. Sixty-nine patients underwent elective surgery and 39 endured emergent operations. The most frequent indications (87 patients, 80.6%) for surgical treatment were urinary tract infection and infected cysts. The median length of hospital stay for group I and group II patients amounted to 8 days (IQR: 7.5–9) and 12.5 days (IQR: 9–16.5), respectively (<i>p</i> &#x3c; 0.001). However, comparing the patients operated on electively, the actual difference in the length of hospital stay was inconsiderable: median 8 days (IQR: 7–9) in group I and 9 days (IQR: 9–11.5) in group II. The median duration of the operation was significantly (<i>p</i> &#x3c; 0.001) longer in group I amounting to 217.5 min (IQR: 197.5–305) than in group II equalling 115 min (IQR: 107.5–145). The frequency of postoperative complications, lethal outcomes, and blood loss volume did not statistically significantly differ depending on the surgical approach. Only patients operated on emergency underwent releparotomy due to intraoperative large bowel injury. Lethal outcomes (<i>n</i> = 18, 16.7%) after surgery were observed only in emergent patients. Sepsis prior to surgery, systemic inflammation response syndrome (SIRS) with the CRP level above 173 mg/mL, prolonged preoperative antibacterial therapy, and undiagnosed large bowel injury were associated with a lethal outcome after BN. <b><i>Conclusion:</i></b> The results of open and laparoscopic BN in elective surgery were comparable. Emergency operations for infected renal cysts and SIRS were associated with increased incidence of large bowel injury and lethal outcomes.

Pentapeptide IKVAV-engineered hydrogels for neural stem cell attachment

2021 ◽  
Author(s):  
Yixia Yin ◽  
Wenwu Wang ◽  
Qi Shao ◽  
Binbin Li ◽  
Dan Yu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Attachment ◽  
Injury Repair ◽  
Cord Injury ◽  
Proliferation Ability

A IKVAV-functionalized hydrogel is developed. It not only enhances neural stem cell (NSC) attachment, growth, and differentiation, but also maintains the proliferation ability of the NSC spheroids in the hydrogel for spinal cord injury repair.

Sign in / Sign up

Export Citation Format

Share Document