Efficacy of anterior cervical fusion: Comparison of titanium cages, polyetheretherketone (PEEK) cages and autogenous bone grafts

✓ The authors describe the surgical technique of anterior cervical fusion using bone grafts obtained from cervical vertebral bodies. This series consisted of 90 patients with cervical intervertebral disc disease suffering from cervical spondylotic myelopathy. Thirty-five patients were operated on at one level, 33 at two levels, and 22 at three levels. Postoperative x-ray films showed solid bone fusion in all patients at a mean follow-up time of 24 months (range 1 year to 3 years 6 months). Anterior angulation was found in four (4.4%) of the 90 patients. This surgical procedure has two major advantages: 1) there are no complications related to the iliac donor site, allowing early patient mobilization; and 2) the extensive posterior spur can be removed safely and easily under a wide operative field without damaging the spinal cord and nerve roots.

Download Full-text

Growth Dynamic of Allogeneic and Autogenous Bone Grafts in a Vertical Model

Brazilian Dental Journal ◽

10.1590/0103-6440201801994 ◽

2018 ◽

Vol 29 (4) ◽

pp. 325-334 ◽

Cited By ~ 2

Author(s):

Julio Leonardo de Oliveira Lima ◽

Daniel Isaac Sendyk ◽

Wilson Roberto Sendyk ◽

Cristiane Ibanhes Polo ◽

Luciana Correa ◽

...

Keyword(s):

Bone Formation ◽

Bone Growth ◽

Pure Titanium ◽

Bone Grafts ◽

Autogenous Bone ◽

Growth Dynamic ◽

Freeze Dried ◽

Fresh Frozen ◽

Hollow Cylinders ◽

Autogenous Bone Grafts

Abstract Several techniques have been proposed for vertical bone regeneration, and many of them use bone autogenous and allogeneic grafts. The purpose of this study was to compare demineralised freeze-dried bone allografts (DFDBA), fresh-frozen (FF) allografts, autogenous bone grafts to find differences between volumetric and histological quantity of bone formation and vertical bone growth dynamic. A vertical tissue regeneration bone model was performed in rabbit calvarias under general anaesthesia. Four hollow cylinders of pure titanium were screwed onto external cortical bone calvarias in eight rabbits. Each one of the cylinders was randomly filled with one intervention: DFDBA, FF, autogenous bone, or left to be filled with blood clot (BC) as control. Allogeneic grafts were obtained from a ninth animal following international standardised protocols for the harvesting, processing, and cryopreservation of allografts. Autogenous graft was obtained from the host femur scraping before adapting hollow cylinders. Animals were euthanized at 13 weeks. Vertical volume was calculated after probe device measurements of the new formed tissue inside the cylinders and after titanium cylinders were removed. Histomorphometry and fluorochrome staining were used to analyse quantity and dynamic of bone formation, respectively. Results showed that DFDBA and fresh-frozen bone improved the velocity and the quantity of bone deposition in distant portions of the basal plane of grafting. Remaining material in allograft groups was more intense than in autogenous group. Both allografts can be indicated as reliable alternatives for volume gain and vertical bone augmentation.

Download Full-text

Long-term results of mandibular reconstruction with autogenous bone grafts and oral implants after tumor resection

Clinical Oral Implants Research ◽

10.1111/j.1600-0501.2008.01542.x ◽

2008 ◽

Vol 19 (10) ◽

pp. 1074-1080 ◽

Cited By ~ 72

Author(s):

Matteo Chiapasco ◽

Giacomo Colletti ◽

Eugenio Romeo ◽

Marco Zaniboni ◽

Roberto Brusati

Keyword(s):

Tumor Resection ◽

Bone Grafts ◽

Mandibular Reconstruction ◽

Long Term Results ◽

Autogenous Bone ◽

Oral Implants ◽

Autogenous Bone Grafts

Download Full-text

Volume Changes of Iliac Crest Autogenous Bone Grafts After Vertical and Horizontal Alveolar Ridge Augmentation of Atrophic Maxillas and Mandibles: A 6-Year Computerized Tomographic Follow-Up

Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.joms.2012.07.040 ◽

2012 ◽

Vol 70 (11) ◽

pp. 2559-2565 ◽

Cited By ~ 59

Author(s):

Carolina Sbordone ◽

Paolo Toti ◽

Franco Guidetti ◽

Luigi Califano ◽

Angela Santoro ◽

...

Keyword(s):

Iliac Crest ◽

Bone Grafts ◽

Autogenous Bone ◽

Alveolar Ridge ◽

Volume Changes ◽

Alveolar Ridge Augmentation ◽

Ridge Augmentation ◽

Autogenous Bone Grafts

Download Full-text

Osteogenic Potential of Autogenous Bone Grafts Harvested with Four Different Surgical Techniques

Journal of Dental Research ◽

10.1177/0022034511422718 ◽

2011 ◽

Vol 90 (12) ◽

pp. 1428-1433 ◽

Cited By ~ 61

Author(s):

R.J. Miron ◽

E. Hedbom ◽

N. Saulacic ◽

Y. Zhang ◽

A. Sculean ◽

...

Keyword(s):

Cell Attachment ◽

Surgical Techniques ◽

Bone Grafts ◽

Osteogenic Potential ◽

Autogenous Bone ◽

Mrna Levels ◽

Alizarin Red ◽

Osteogenic Response ◽

Autogenous Bone Grafts

The osteogenic potential of autogenous bone grafts is superior to that of allografts and xenografts because of their ability to release osteoinductive growth factors and provide a natural osteoconductive surface for cell attachment and growth. In this in vitro study, autogenous bone particles were harvested by four commonly used techniques and compared for their ability to promote an osteogenic response. Primary osteoblasts were isolated and seeded on autogenous bone grafts prepared from the mandibles of miniature pigs with a bone mill, piezo-surgery, bone scraper, and bone drill (bone slurry). The osteoblast cultures were compared for their ability to promote cell attachment, proliferation, and differentiation. After 4 and 8 hrs, significantly higher cell numbers were associated with bone mill and bone scraper samples compared with those acquired by bone slurry and piezo-surgery. Similar patterns were consistently observed up to 5 days. Furthermore, osteoblasts seeded on bone mill and scraper samples expressed significantly elevated mRNA levels of collagen, osteocalcin, and osterix at 3 and 14 days and produced more mineralized tissue as assessed by alizarin red staining. These results suggest that the larger bone graft particles produced by bone mill and bone scraper techniques have a higher osteogenic potential than bone slurry and piezo-surgery.

Download Full-text