Aortic pulsation prevents the development of ossification of anterior longitudinal ligament toward the aorta in patients with diffuse idiopathic skeletal hyperostosis (DISH) in Japanese: Results of chest CT-based cross-sectional study

AbstractThe purpose of this study was to examine the prevalence and characteristics of thoracic diffuse idiopathic skeletal hyperostosis (T-DISH) in the Black patients using the computed tomography (CT) analysis. This study is a cross-sectional study. All patients who underwent chest CT for the trauma screening and whose race was categorized as “Black” on the questionnaire were recruited in the study from Mar 2019 to Mar 2020. Demographic data, including age, sex, body mass index (BMI), and presence of diabetes mellitus (DM), were recorded. A total of 3299 Black patients (1507 women and 1792 men) were included for the analysis. The prevalence of T-DISH was 7.7% (255 patients), with 8.6% for females and 7.0% for males. The highest prevalence was observed in patients at the age of 70 years (11.7%), followed by the age of 80 years (10.5%). The highest prevalence level of T-DISH segment was at T8, followed by T9, and T7. The most frequent number of contiguous vertebrae was seven (21%). BMI was not associated with T-DISH. The presence of DM was significantly higher in male patients with T-DISH than those without T-DISH (P = 0.02).

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Identifying Clinicoradiological Phenotypes in Diffuse Idiopathic Skeletal Hyperostosis: A Cross-Sectional Study

Medicina ◽

10.3390/medicina57101005 ◽

2021 ◽

Vol 57 (10) ◽

pp. 1005

Author(s):

Teresa Clavaguera ◽

Patrícia Reyner ◽

Maria Buxó ◽

Marta Valls ◽

Eulàlia Armengol ◽

...

Keyword(s):

Comparative Analysis ◽

Diffuse Idiopathic Skeletal Hyperostosis ◽

Cross Sectional Study ◽

Classification Criteria ◽

Sectional Study ◽

New Classification ◽

Extensive Disease ◽

Cross Sectional ◽

Asymptomatic Patients ◽

Mixed Pattern

Background and objectives: Diffuse idiopathic skeletal hyperostosis (DISH) is a bone formation disease in which only skeletal signs are considered in classification criteria. The aim of the study was to describe different phenotypes in DISH patients based on clinicoradiological features. Materials and Methods: We evaluated 97 patients who met the Resnick or modified Utsinger classification criteria for DISH and were diagnosed at our hospital from 2004 to 2015. Patients were stratified into: (a) peripheral pattern (PP)—Resnick criteria not met but presenting ≥3 peripheral enthesopathies; (b) axial pattern (AP)—Resnick criteria met but <3 enthesopathies; and (c) mixed pattern (MP)—Resnick criteria met with ≥3 enthesopathies. Statistical analysis was carried out to identify variables that might predict classification in a given group. Results: Fifty-six of the 97 patients included (57.7%) were male and 72.2% fulfilled the Resnick criteria. Applying our classification, 39.7% were stratified as MP, 30.9% as AP and 29.4% as PP. Clinical enthesopathy was reported in 40.2% of patients during the course of the disease. Sixty-eight patients were included in a comparative analysis of variables between DISH patterns. The results showed a predominance of women (p < 0.004), early onset (p < 0.03), hip involvement (p < 0.003) and enthesitis (p < 0.001) as hallmarks of PP. Asymptomatic patients were most frequently observed in AP (28.6%, MP 3.8%, PP 5.0%) while MP was characterized by a more extensive disease. Conclusions: We believe DISH has distinct phenotypes and describe a PP phenotype that is not usually considered. Extravertebral manifestations should be included in the new classification criteria in order to cover the entire spectrum of the disease.

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Cross-sectional study of chest CT-scan findings in patients affected by SARS-CoV-2 in a tertiary care health centre in Guntur Andhra Pradesh

IP Indian Journal of Immunology and Respiratory Medicine ◽

10.18231/j.ijirm.2021.012 ◽

2021 ◽

Vol 6 (1) ◽

pp. 54-57

Author(s):

P V Kalyan Kumar ◽

Y Vivekanand

Keyword(s):

Ct Scan ◽

Andhra Pradesh ◽

Health Centre ◽

Tertiary Care ◽

Cross Sectional Study ◽

Chest Ct ◽

Sectional Study ◽

Cross Sectional ◽

Care Health ◽

Chest Ct Scan

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Evaluation of Chest CT Scan as a Screening and Diagnostic Tool in Trauma Patients with Coronavirus Disease 2019 (COVID-19): A Cross-Sectional Study

Emergency Medicine International ◽

10.1155/2021/4188178 ◽

2021 ◽

Vol 2021 ◽

pp. 1-8

Author(s):

Hossein Abdolrahimzadeh Fard ◽

Salahaddin Mahmudi-Azer ◽

Sepideh Sefidbakht ◽

Pooya Iranpour ◽

Shahram Bolandparvaz ◽

...

Keyword(s):

Ct Scan ◽

Negative Predictive Value ◽

Predictive Value ◽

Cross Sectional Study ◽

Chest Ct ◽

Trauma Patients ◽

Ct Scanner ◽

Sectional Study ◽

Cross Sectional ◽

Chest Ct Scan

Background. The lack of enough medical evidence about COVID-19 regarding optimal prevention, diagnosis, and treatment contributes negatively to the rapid increase in the number of cases globally. A chest computerized tomography (CT) scan has been introduced as the most sensitive diagnostic method. Therefore, this research aimed to examine and evaluate the chest CT scan as a screening measure of COVID-19 in trauma patients. Methods. This cross-sectional study was conducted in Rajaee Hospital in Shiraz from February to May 2020. All patients underwent unenhanced CT with a 16-slice CT scanner. The CT scans were evaluated in a blinded manner, and the main CT scan features were described and classified into four groups according to RSNA recommendation. Subsequently, the first two Radiological Society of North America (RSNA) categories with the highest probability of COVID-19 pneumonia (i.e., typical and indeterminate) were merged into the “positive CT scan group” and those with radiologic features with the least probability of COVID-19 pneumonia into “negative CT scan group.” Results. Chest CT scan had a sensitivity of 68%, specificity of 56%, positive predictive value of 34.8%, negative predictive value of 83.7%, and accuracy of 59.3% in detecting COVID-19 among trauma patients. Moreover, for the diagnosis of COVID-19 by CT scan in asymptomatic individuals, a sensitivity of 100%, specificity of 66.7%, and negative predictive value of 100% were obtained ( p value: 0.05). Conclusion. Findings of the study indicated that the CT scan’s sensitivity and specificity is less effective in diagnosing trauma patients with COVID-19 compared with nontraumatic people.

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CLINICAL CORRELATION AND AGREEMENT BETWEEN THE CHEST CT SCAN AND CHEST X-RAY FINDINGS IN TUBERCULIN-POSITIVE CHILDREN: A PROSPECTIVE CROSS SECTIONAL STUDY

CHEST Journal ◽

10.1378/chest.136.4_meetingabstracts.40s-a ◽

2009 ◽

Vol 136 (4) ◽

pp. 40S

Author(s):

Beverly D. Delacruz ◽

Nerissa A. Deleon ◽

Milagros S. Bautista ◽

Fernando Ayuyao ◽

Teresita Deguia

Keyword(s):

Ct Scan ◽

Cross Sectional Study ◽

Chest Ct ◽

Clinical Correlation ◽

Sectional Study ◽

Cross Sectional ◽

X Ray ◽

Chest X Ray ◽

Chest Ct Scan

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THU0489 HIP INVOLVEMENT IN DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH): CROSS-SECTIONAL STUDY

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2020-eular.2590 ◽

2020 ◽

Vol 79 (Suppl 1) ◽

pp. 482.1-482

Author(s):

T. Clavaguera ◽

E. Armengol ◽

M. Buxó ◽

M. Valls ◽

E. DE Cendra ◽

...

Keyword(s):

Diffuse Idiopathic Skeletal Hyperostosis ◽

Cross Sectional Study ◽

Classification Criteria ◽

Bivariate Analysis ◽

Correct Identification ◽

Sectional Study ◽

Cross Sectional ◽

Disease Evolution ◽

Female Sex ◽

Mixed Pattern

Background:In DISH or Forestier-Rotés disease, hip involvement is often misdiagnosed as hip osteoarthritis, especially when it is the initial manifestation of the disease or in patients with scarce vertebral signs. At present, a correct identification of this entity may suppose considerable therapeutic implications1.Objectives:The purpose of this study was to assess the prevalence and characteristics of hip involvement in our cohort of patients with DISH and evaluate the association of this extra-spinal manifestation with the variables studied.Methods:We carried out a cross-sectional study in DISH patients who met Resnick and / or Utsinger classification criteria. We collected demographic, anthropometric, clinical and imaging data. Hip involvement was defined as the characteristic irregular bony excrescences above acetabulum. The cohort was divided between patients with and without hip involvement. A univariate descriptive analysis was performed with means and standard deviations, absolute frequencies and percentages. The normality of the data was checked using the Shapiro-Willis test. The bivariate analysis, for the qualitative variables, the χ2test or Fisher’s exact test were identified. For the quantitative variables, the Student’s t-test was used if the data followed a normal distribution, and otherwise using the Mann-Whitney U test.Results:Of the 58 patients included, 67.2% were male. The median age was 69.4 years (44-89). The average time of disease evolution was 14.8 (+9.3) years. Although the most frequent initial symptom was thoraco-lumbar pain (39.7%), hip complaints were initially present in 13.8%. 22,6% of patients did not fulfil Resnick classification criteria. Hip involvement was identified in 53.4% and a 61,3% the cartilage space were preserved. In the bivariate analysis, hip involvement was associated with female sex, a reduction in the intermaleolar distance (IM) and the presence of certain enthesopathies (greater trochanter, superior iliac spines and distal patellar entheses). The acetabular ossifications were significantly related to the mixed pattern compared to the other possible phenotypes of the disease.Conclusion:Hip involvement has been described in more than 50% of our patients. We found out that it was associated with female sex and a more broad ossification phenotype (mixed pattern). The measurement of IM distance could be useful for the clinical evaluation of this condition. Ossifications of other pelvic ring entheses were more observed in association with acetabular hyperostosis than other peripheral insertions.References:[1]Jung-Mo Hwang, Deuk-Soo Hwang, Chan Kang, Woo-Yong Lee, et al. Arthroscopic Treatment for Femoroacetabular Impingement with Extraspinal Diffuse Idiopathic Skeletal Hyperostosis. Clin Orthop Surg 2019; 11: 275–281.Disclosure of Interests: :Teresa Clavaguera Speakers bureau: novartis, BMS, Faes, Eulàlia Armengol Speakers bureau: Novartis, Maria Buxó: None declared, Marta Valls: None declared, Eulàlia DE CENDRA: None declared, Patricia Reyner Speakers bureau: Faes, Sanofi

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Evaluation of Chest CT scan as a screening and diagnostic tool in trauma patients with coronavirus disease 2019 (COVID-19): a cross-sectional study in southern Iran

10.21203/rs.3.rs-110402/v2 ◽

2020 ◽

Author(s):

Hossein Abdolrahimzadeh Fard ◽

Salahaddin Mahmudi-Azer ◽

Sepideh Sefidbakht ◽

Pooya Iranpour ◽

Shahram Bolandparvaz ◽

...

Keyword(s):

Ct Scan ◽

Negative Predictive Value ◽

Predictive Value ◽

Cross Sectional Study ◽

Chest Ct ◽

Trauma Patients ◽

Ct Scanner ◽

Sectional Study ◽

Cross Sectional ◽

Chest Ct Scan

Abstract Purpose: The lack of enough medical evidence about COVID-19 regarding optimal prevention, diagnosis, and treatment contributes negatively to the rapid increase in the number of cases globally. A chest computerized tomography (CT) scan has been introduced as the most sensitive diagnostic method. Therefore, this research aimed to examine and evaluate the chest CT scan as a screening measure of COVID-19 in trauma patients.Methods: This cross-sectional study was conducted in Rajaee Hospital in Shiraz from February to May 2020. All patients underwent unenhanced CT with a 16-slice CT scanner. The CT-scans were evaluated in a blinded manner and main CT scan features were described and classified into four groups according to RSNA recommendation. Subsequently, the first two RSNA categories with the highest probability of COVID pneumonia (i.e. typical and indeterminate) were merged into the “positive CT scan group” and those with radiologic features with the least probability of COVID pneumonia into “negative CT scan group”.Results: Chest CT scan had a sensitivity (68%), specificity (56%), positive predictive value (34.8%), negative predictive value (83.7%), and accuracy (59.3%) in detecting COVID-19 among trauma patients. Also, for the diagnosis of COVID-19 by CT scan in asymptomatic individuals a sensitivity of 100% and a specificity of 66.7% and a negative predictive value of 100% was obtained.Conclusion: Findings of the study indicated that the CT scan's sensitivity and specificity is less effective in diagnosing trauma patients with COVID-19 in comparison to non-traumatic people.

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Clinical predictors of abnormal chest CT scan findings following blunt chest trauma: A cross-sectional study

Chinese Journal of Traumatology ◽

10.1016/j.cjtee.2019.07.007 ◽

2020 ◽

Vol 23 (1) ◽

pp. 51-55

Author(s):

Saeed Safari ◽

Melina Farbod ◽

Hamidreza Hatamabadi ◽

Mahmoud Yousefifard ◽

Navid Mokhtari

Keyword(s):

Ct Scan ◽

Blunt Chest Trauma ◽

Chest Trauma ◽

Cross Sectional Study ◽

Chest Ct ◽

Sectional Study ◽

Clinical Predictors ◽

Cross Sectional ◽

Abnormal Chest ◽

Chest Ct Scan

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Aortic-vertebral interaction in ankylosing spondylitis: syndesmophyte development at the juxta-aortic vertebral rim

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2018-214675 ◽

2019 ◽

Vol 78 (7) ◽

pp. 922-928 ◽

Cited By ~ 2

Author(s):

Sovira Tan ◽

Abhijit Dasgupta ◽

John A Flynn ◽

Michael M Ward

Keyword(s):

Ankylosing Spondylitis ◽

Thoracic Spine ◽

Diffuse Idiopathic Skeletal Hyperostosis ◽

Cross Sectional Study ◽

Ct Scans ◽

Sectional Study ◽

Intervertebral Disc Space ◽

Disc Space ◽

Cross Sectional ◽

Mechanical Factors

ObjectivesThe aorta inhibits paravertebral ossification in diffuse idiopathic skeletal hyperostosis. We investigated if syndesmophytes in ankylosing spondylitis (AS) occurred less often at the vertebral rim near the aorta.MethodsWe performed thoracolumbar CT scans in 60 subjects in this cross-sectional study. The mid-thoracic spine was also scanned in 22 subjects. We divided the rim of each intervertebral disc space (IDS) into 72 angular sectors, each of 5°. We computed syndesmophyte height in each sector, and the distance from the sector to the aorta. We evaluated if syndesmophyte size or frequency in a sector was associated with its distance from the aorta.ResultsIn the 180° region of the vertebral rim centered on the sector closest to the aorta, syndesmophyte height and/or frequency varied with the distance of the sector to the aorta, with the lowest frequency and smallest mean syndesmophyte height at the sector along the rim nearest the aorta. Additionally, syndesmophytes were less common in subjects and at IDSs where the aorta was anatomically closer to the vertebra. No syndesmophytes were present in the sector closest to the aorta in subjects whose aorta-vertebral distance was less than 2 mm, but syndesmophytes were progressively more common among subjects whose aortas lay further from the rim.ConclusionsSyndesmophytes occurred less commonly and were smaller at the thoracolumbar vertebral rim near the aorta. These findings suggest that mechanical factors extrinsic to the spine and not solely vertebral inflammation, influence syndesmophyte development in AS.

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