Increase in pancreatic enzymes following spinal alignment changes in the thoracolumbar junction: Potential for acute pancreatitis after kyphosis correction

2020 ◽  
Author(s):  
Masahiro Iinuma ◽  
Tsutomu Akazawa ◽  
Yoshiaki Torii ◽  
Jun Ueno ◽  
Tasuku Umehara ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Pancreatic Enzymes ◽  
Thoracolumbar Junction ◽  
Spinal Alignment ◽  
Kyphosis Correction ◽  
Junction Potential

scholarly journals A Rare Cause of Acute Pancreatitis: Intramural Duodenal Hematoma

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Hemant Goyal ◽  
Umesh Singla ◽  
Roli R. Agrawal
Keyword(s):  
Acute Pancreatitis ◽  
Emergency Room ◽  
Outlet Obstruction ◽  
Interesting Case ◽  
Pancreatic Enzymes ◽  
Initial Evaluation ◽  
Healthy Male ◽  
Imaging Studies ◽  
Acute Gastritis ◽  
Duodenal Hematoma

We describe an interesting case of intramural duodenal hematoma in an otherwise healthy male who presented to emergency room with gradually progressive abdominal pain, nausea, and vomiting. This condition was missed on initial evaluation and patient was discharged from emergency room with diagnosis of acute gastritis. After 3 days, patient came back to emergency room and abdominal imaging studies were conducted which showed that patient had intramural duodenal hematoma associated with gastric outlet obstruction and pancreatitis. Hematoma was the cause of acute pancreatitis as pancreatic enzymes levels were normal at the time of first presentation, but later as the hematoma grew in size, it caused compression of pancreas and subsequent elevation of pancreatic enzymes. We experienced a case of pancreatitis which was caused by intramural duodenal hematoma. This case was missed on initial evaluation. We suggest that physicians should be more vigilant about this condition.

scholarly journals Asymptomatic and Persistent Elevation of Pancreatic Enzymes in an Ulcerative Colitis Patient

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Elisa Liverani ◽  
Filippo Leonardi ◽  
Lucia Castellani ◽  
Carla Cardamone ◽  
Andrea Belluzzi
Keyword(s):  
Ulcerative Colitis ◽  
Acute Pancreatitis ◽  
Serum Amylase ◽  
Drug Dosage ◽  
Pancreatic Disease ◽  
Pancreatic Enzymes ◽  
Pancreatic Damage ◽  
Bowel Diseases ◽  
One Year ◽  
Asymptomatic Elevation

Azathioprine has been extensively used in the management of inflammatory bowel diseases. It might cause pancreatic damage in the form of either asymptomatic elevation in serum amylase/lipase or overt acute pancreatitis. Here we report the case of a 61-year-old patient with ulcerative colitis who had been treated with azathioprine for three years, achieving clinical remission. During treatment he presented an asymptomatic elevation of serum pancreatic enzymes, without any signs of pancreatitis at imaging. This evidence brought us to reassess the drug dosage, without achieving a normalization of biochemical analysis. Autoimmune pancreatitis was excluded. One year after the suspension of azathioprine, we still face persistent high levels of amylase/lipase. Normalization of enzymatic values in patients who develop intolerance to azathioprine, in the form of either asymptomatic elevation in serum amylase/lipase or overt acute pancreatitis, is usually achieved in about two months after stopping drug intake. Asymptomatic elevation in serum pancreatic enzymes in the absence of pancreatic disease is reported in the literature and defined as “Gullo’s syndrome,” but nobody of the subjects studied had been treated in the past with pancreatotoxic drugs. Might this case be defined as “benign pancreatic hyperenzymemia”?

Pancreatic disease

2018 ◽  
Author(s):  
Satish Keshav ◽  
Alexandra Kent
Keyword(s):  
Acute Pancreatitis ◽  
Inflammatory Process ◽  
Pancreatic Disease ◽  
Pancreatic Enzymes ◽  
Surrounding Tissue ◽  
Systemic Effects

Acute pancreatitis is an acute inflammatory process of the pancreas and is potentially reversible. It is characterized by oedema and necrosis of peripancreatic fat and may progress to necrosis of glandular and surrounding tissue. Activation of pancreatic enzymes leads to pancreatic autodigestion and systemic effects.

The Role of Pancreatic Enzymes in the Pathogenesis of Acute Pancreatitis

1962 ◽  
Vol 43 (1) ◽  
pp. 60-70 ◽  
Author(s):  
Ivan T. Beck ◽  
Emery J. Pinter ◽  
Jeno Solymar ◽  
Richard D. McKenna ◽  
A.C. Ritchie
Keyword(s):  
Acute Pancreatitis ◽  
Pancreatic Enzymes

A rare case of acute pancreatitis: a diagnostic conundrum and unusual complications

2020 ◽  
Vol 93 (1) ◽  
pp. 1-5
Author(s):  
Bartłomiej Strzelec ◽  
Piotr Chmielewski ◽  
Martyna Strzelec ◽  
Renata Taboła
Keyword(s):  
Acute Pancreatitis ◽  
Rare Case ◽  
Good Condition ◽  
Serum Levels ◽  
Pancreatic Enzymes ◽  
First Episode ◽  
Surgical Ward ◽  
History Of ◽  
Idiopathic Acute Pancreatitis ◽  
Excessive Alcohol

A 63-year-old man with a history of recurrent idiopathic acute pancreatitis (AP) was admitted to our surgical ward due to severe abdominal pain. He denied chronic excessive alcohol use. Other typical causes of AP, such as gallstones, hypertriglyceridemia, and trauma, were ruled out. After considering all possible etiologies, the most likely factor producing AP was medication that had been administered to him two weeks before the very first episode of the disease. Medication should always be considered as a possible trigger of AP, especially if the first episode occurs shortly after drug administration and the etiology is unclear. During patient’s hospitalization, laboratory reports revealed significant fluctuations in the serum levels of pancreatic enzymes, which can be attributed to recurrent bacteremia. After the 30-day period of hospitalization and long-lasting antibiotic therapy, he was discharged in a good condition with normal levels of serum pancreatic enzymes.

Survival of a case of pre-eclampsia complicated with acute fatty liver of pregnancy and acute pancreatitis

2021 ◽  
pp. 004947552110418
Author(s):  
Omkolsoum M Alhaddad ◽  
Maha M Elsabaawy ◽  
Eman A Rewisha ◽  
Omar A Shaarawy ◽  
Hanaa M Badran ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Fatty Liver ◽  
Pancreatic Head ◽  
Clinical Suspicion ◽  
Pancreatic Enzymes ◽  
Sonographic Appearance ◽  
Acute Fatty Liver ◽  
Criteria For Diagnosis

Acute fatty liver of pregnancy (AFLP) and acute pancreatitis are peculiar complications of pregnancy. When acute pancreatitis occurs co-incidentally with acute fatty liver of pregnancy, mortality is high. Here, we report a case of a 22-year-old lady in her 36th week of gestation, who presented with pre-eclampsia, acute fatty liver of pregnancy and acute pancreatitis. She fulfilled six Swansea criteria for diagnosis of AFLP, and the diagnosis of acute pancreatitis was based on clinical suspicion, elevated pancreatic enzymes and the sonographic appearance of a swollen pancreatic head.

scholarly journals Novel Method for Evaluation of Sagittal Spinal Alignment Using Cluster Analysis of Slope of Each Vertebra.

2021 ◽  
Author(s):  
Yoshitaka Matsubayashi ◽  
Yasushi Oshima ◽  
Yuki Taniguchi ◽  
Toru Doi ◽  
So Kato ◽  
...  
Keyword(s):  
Cluster Analysis ◽  
Sagittal Alignment ◽  
Thoracolumbar Junction ◽  
Sacral Slope ◽  
Spinal Alignment ◽  
Sagittal Spinal Alignment ◽  
Significant Difference ◽  
Novel Method ◽  
And Cluster Analysis ◽  
Whole Spine

Abstract Background: The parameters of sagittal spinal alignment proposed to date measure only the specific sectional angle or the specific sectional distance of the entire spine. To evaluate the alignment of the entire spine without segmentation, we sought to measure and analyze the slope of each vertebral body from skull to pelvis. The purpose of this study was to confirm the effectiveness of this novel analytic method for the evaluation of spinal alignment that considers the slope of each spinal vertebra using graph and cluster analysis.Methods: Every spinal slope from McGregor’s slope to the sacral slope of 88 patients who underwent standing whole spine radiography was measured. Subsequently, we conducted cluster analysis of each spinal slope to understand the characteristics of sagittal alignment.Results: Cluster analysis of whole spinal slopes did not provide useful results in this study because the number of cases per cluster was small due to the large number of parameters. Therefore, we focused the cluster analysis on only the cervical spine slopes. Then, we categorized cervical alignment into four groups (named Normal, Mismatch, Straight, and Sigmoid) based on the results of the cluster analysis. Patients in the Normal and Mismatch groups were older and had lower lumbar apex (L4), apparent lordo-kyphosis around the thoracolumbar junction, and high thoracic kyphosis (TK). Patients in the straight and sigmoid groups were younger, had a higher lumbar apex (L3), flat thoracolumbar junction, and low TK. There was no significant difference between the four groups with respect to pelvic incidence (PI) or pelvic tilt (PT).Conclusion: We proposed a novel method for visually understanding sagittal alignment. Using this analysis method, differences and similarities of sagittal alignment between each group can be easily identified. More detailed analysis of the whole spine may be possible by increasing the number of cases.

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