scholarly journals Socioeconomic inequality in preterm birth in four Brazilian birth cohort studies

2018 ◽  
Vol 94 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Ana Daniela Izoton de Sadovsky ◽  
Alicia Matijasevich ◽  
Iná S. Santos ◽  
Fernando C. Barros ◽  
Angelica Espinosa Miranda ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Cohort Studies ◽  
Birth Cohort ◽  
Socioeconomic Inequality

scholarly journals Socioeconomic inequality in preterm birth in four Brazilian birth cohort studies

2018 ◽  
Vol 94 (1) ◽  
pp. 15-22
Author(s):  
Ana Daniela Izoton de Sadovsky ◽  
Alicia Matijasevich ◽  
Iná S. Santos ◽  
Fernando C. Barros ◽  
Angelica Espinosa Miranda ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Cohort Studies ◽  
Birth Cohort ◽  
Socioeconomic Inequality

scholarly journals Development of a data classification system for preterm birth cohort studies: the RECAP Preterm project

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Deborah Bamber ◽  
Helen E. Collins ◽  
Charlotte Powell ◽  
Gonçalo Campos Gonçalves ◽  
Samantha Johnson ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Cohort Studies ◽  
Birth Cohort ◽  
Classification System ◽  
Statistical Power ◽  
Small Sample ◽  
Data Mapping ◽  
Consultation Process ◽  
Long Term Impact ◽  
Data Harmonisation

Abstract Background The small sample sizes available within many very preterm (VPT) longitudinal birth cohort studies mean that it is often necessary to combine and harmonise data from individual studies to increase statistical power, especially for studying rare outcomes. Curating and mapping data is a vital first step in the process of data harmonisation. To facilitate data mapping and harmonisation across VPT birth cohort studies, we developed a custom classification system as part of the Research on European Children and Adults born Preterm (RECAP Preterm) project in order to increase the scope and generalisability of research and the evaluation of outcomes across the lifespan for individuals born VPT. Methods The multidisciplinary consortium of expert clinicians and researchers who made up the RECAP Preterm project participated in a four-phase consultation process via email questionnaire to develop a topic-specific classification system. Descriptive analyses were calculated after each questionnaire round to provide pre- and post- ratings to assess levels of agreement with the classification system as it developed. Amendments and refinements were made to the classification system after each round. Results Expert input from 23 clinicians and researchers from the RECAP Preterm project aided development of the classification system’s topic content, refining it from 10 modules, 48 themes and 197 domains to 14 modules, 93 themes and 345 domains. Supplementary classifications for target, source, mode and instrument were also developed to capture additional variable-level information. Over 22,000 individual data variables relating to VPT birth outcomes have been mapped to the classification system to date to facilitate data harmonisation. This will continue to increase as retrospective data items are mapped and harmonised variables are created. Conclusions This bespoke preterm birth classification system is a fundamental component of the RECAP Preterm project’s web-based interactive platform. It is freely available for use worldwide by those interested in research into the long term impact of VPT birth. It can also be used to inform the development of future cohort studies.

scholarly journals Recomposing persons: Scavenging and storytelling in a birth cohort archive

2021 ◽  
pp. 095269512199539
Author(s):  
Penny Tinkler ◽  
Resto Cruz ◽  
Laura Fenton
Keyword(s):  
Life Course ◽  
Cohort Studies ◽  
Birth Cohort ◽  
Quantitative Data ◽  
Population Level ◽  
Relational Embeddedness ◽  
The Life Course ◽  
Over Time

Birth cohort studies can be used not only to generate population-level quantitative data, but also to recompose persons. The crux is how we understand data and persons. Recomposition entails scavenging for various (including unrecognised) data. It foregrounds the perspective and subjectivity of survey participants, but without forgetting the partiality and incompleteness of the accounts that it may generate. Although interested in the singularity of individuals, it attends to the historical and relational embeddedness of personhood. It examines the multiple and complex temporalities that suffuse people’s lives, hence departing from linear notions of the life course. It implies involvement, as well as reflexivity, on the part of researchers. It embraces the heterogeneity and transformations over time of scientific archives and the interpretive possibilities, as well as incompleteness, of birth cohort studies data. Interested in the unfolding of lives over time, it also shines light on meaningful biographical moments.

scholarly journals Work-Family Life Courses and Psychological Distress: Evidence from Three British Birth Cohort Studies

2021 ◽  
pp. 100429
Author(s):  
Anne McMunn ◽  
Rebecca Lacey ◽  
Diana Worts ◽  
Diana Kuh ◽  
Peggy McDonough ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Cohort Studies ◽  
Birth Cohort ◽  
Family Life ◽  
Life Courses ◽  
Work Family

scholarly journals Cognitive Performance and Cerebrospinal Fluid Markers in Preclinical Alzheimer’s Disease: Results from the Gothenburg H70 Birth Cohort Studies

2021 ◽  
Vol 79 (1) ◽  
pp. 225-235
Author(s):  
Maya Arvidsson Rådestig ◽  
Johan Skoog ◽  
Henrik Zetterberg ◽  
Jürgen Kern ◽  
Anna Zettergren ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Cohort Studies ◽  
Cognitive Performance ◽  
Birth Cohort ◽  
Population Based ◽  
Tau Pathology ◽  
Preclinical Alzheimer’S Disease ◽  
Preclinical Ad

Background: We have previously shown that older adults with preclinical Alzheimer’s disease (AD) pathology in cerebrospinal fluid (CSF) had slightly worse performance in Mini-Mental State Examination (MMSE) than participants without preclinical AD pathology. Objective: We therefore aimed to compare performance on neurocognitive tests in a population-based sample of 70-year-olds with and without CSF AD pathology. Methods: The sample was derived from the population-based Gothenburg H70 Birth Cohort Studies in Sweden. Participants (n = 316, 70 years old) underwent comprehensive cognitive examinations, and CSF Aβ-42, Aβ-40, T-tau, and P-tau concentrations were measured. Participants were classified according to the ATN system, and according to their Clinical Dementia Rating (CDR) score. Cognitive performance was examined in the CSF amyloid, tau, and neurodegeneration (ATN) categories. Results: Among participants with CDR 0 (n = 259), those with amyloid (A+) and/or tau pathology (T+, N+) showed similar performance on most cognitive tests compared to participants with A-T-N-. Participants with A-T-N+ performed worse in memory (Supra span (p = 0.003), object Delayed (p = 0.042) and Immediate recall (p = 0.033)). Among participants with CDR 0.5 (n = 57), those with amyloid pathology (A+) scored worse in category fluency (p = 0.003). Conclusion: Cognitively normal participants with amyloid and/or tau pathology performed similarly to those without any biomarker evidence of preclinical AD in most cognitive domains, with the exception of slightly poorer memory performance in A-T-N+. Our study suggests that preclinical AD biomarkers are altered before cognitive decline.

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