Faecal proteomics in the identification of biomarkers to differentiate canine chronic enteropathies

2021 ◽  
pp. 104452
Author(s):  
Emily L. O'Reilly ◽  
Anita Horvatić ◽  
Josipa Kuleš ◽  
Andrea Gelemanović ◽  
Vladimir Mrljak ◽  
...  
2012 ◽  
Vol 114 (4) ◽  
pp. 412-422 ◽  
Author(s):  
Edgar Corneille Ontsouka ◽  
Iwan Anton Burgener ◽  
Nicole Luckschander-Zeller ◽  
Jürg Walter Blum ◽  
Christiane Albrecht

2013 ◽  
Vol 142 (6) ◽  
pp. 1277-1288 ◽  
Author(s):  
L. MUGHINI-GRAS ◽  
J. H. SMID ◽  
J. A. WAGENAAR ◽  
A. DE BOER ◽  
A. H. HAVELAAR ◽  
...  

SUMMARYMultilocus sequence types (STs) were determined for 232 and 737Campylobacter jejuni/coliisolates from Dutch travellers and domestically acquired cases, respectively. Putative risk factors for travel-related campylobacteriosis, and for domestically acquired campylobacteriosis caused by exotic STs (putatively carried by returning travellers), were investigated. Travelling to Asia, Africa, Latin America and the Caribbean, and Southern Europe significantly increased the risk of acquiring campylobacteriosis compared to travelling within Western Europe. Besides eating chicken, using antacids, and having chronic enteropathies, we identified eating vegetable salad outside Europe, drinking bottled water in high-risk destinations, and handling/eating undercooked pork as possible risk factors for travel-related campylobacteriosis. Factors associated with domestically acquired campylobacteriosis caused by exotic STs involved predominantly person-to-person contacts around popular holiday periods. We concluded that putative determinants of travel-related campylobacteriosis differ from those of domestically acquired infections and that returning travellers may carry several exotic strains that might subsequently spread to domestic populations even through limited person-to-person transmission.


2016 ◽  
Vol 178 (15) ◽  
pp. 368.2-368 ◽  
Author(s):  
K. Allenspach ◽  
C. Culverwell ◽  
D. Chan

2008 ◽  
Vol 49 (1) ◽  
pp. 56-64 ◽  
Author(s):  
LORRIE GASCHEN ◽  
PATRICK KIRCHER ◽  
ANJA STÜSSI ◽  
KARIN ALLENSPACH ◽  
FRÉDÉRIC GASCHEN ◽  
...  

2017 ◽  
Vol 182 (9) ◽  
pp. 258-258 ◽  
Author(s):  
Simona D’Angelo ◽  
Federico Fracassi ◽  
Francesca Bresciani ◽  
Roberta Galuppi ◽  
Alessia Diana ◽  
...  

Saccharomyces boulardii is used to treat acute and chronic enteropathies in humans, but to date, no studies have evaluated the use of this yeast in dogs. The current study, a prospective non-randomised, double-blinded, placebo-controlled study, evaluated the effects of S boulardii in healthy dogs and dogs with chronic enteropathies (CE). Four healthy dogs and 20 dogs with CE were included. In healthy dogs, S boulardii was administered for 10 days. Possible short-term adverse effects were recorded, and quantitative stool cultures for yeasts were performed. In dogs with CE, S boulardii or a placebo was administered in addition to standard treatment protocols. Canine Chronic Enteropathy Clinical Activity Index, abdominal ultrasonography, gastroenteroscopy and histology were performed at the time of diagnosis and after 60 days of treatment. In healthy dogs, S boulardii reached a steady state in five days and was completely eliminated on day 4 after administration. No short-term side effects were seen. Clinical activity index, stool frequency, stool consistency and body condition score improved significantly in dogs with CE receiving S boulardii versus the placebo. In conclusion, S boulardii can be safely used in dogs with CE and seems to achieve better control of clinical signs than standard therapy alone.


1989 ◽  
Vol 30 (1) ◽  
pp. 3-12 ◽  
Author(s):  
R. M. Batt ◽  
E. J. Hall

2004 ◽  
Vol 11 (5) ◽  
pp. 841-848 ◽  
Author(s):  
I. R. Peters ◽  
E. L. Calvert ◽  
E. J. Hall ◽  
M. J. Day

ABSTRACT Selective immunoglobulin A (IgA) deficiency is the most common primary immunodeficiency in humans and may be associated with chronic gastrointestinal disease. This observation has led to the suggestion that the high susceptibility of German shepherd dogs (GSD) to chronic enteropathies is related to a deficiency in mucosal IgA production. Relative deficiencies of IgA has been reported in the serum, saliva, tears, and feces of GSD both with and without alimentary disease; however, the findings of different studies are not consistent. The aim of this study was to confirm whether a relative deficiency of IgA exists in the feces of GSD. Feces were collected from healthy GSD (n = 209), Labrador retrievers (n = 96), beagles (n = 19), and miniature schnauzers (n = 32). Fecal IgA, IgM, and IgG were measured by capture enzyme-linked immunosorbent assays. Fecal IgG concentrations in the four breed groups were not significantly different. IgA concentrations were significantly greater in miniature schnauzers than in GSD (P = 0.0003) and Labradors (P = 0.0004) but not significantly different from those in beagles. IgM concentrations were significantly greater in miniature schnauzers than in GSD (P < 0.0001), Labradors (P < 0.0001), and beagles (P = 0.0098). These findings do not support the hypothesis that GSD have a relative deficiency in fecal IgA. The differences in immunoglobulin concentrations measured from a single defecation, between individuals of the same breed and between breeds, as well as the lack of an internal control molecule, make the determination of a normal reference range for all dogs impossible. Therefore, the usefulness of fecal immunoglobulin quantification for the assessment of intestinal immunoglobulin secretion in dogs is limited.


2018 ◽  
Vol 154 (6) ◽  
pp. S-686-S-687 ◽  
Author(s):  
Dawn D. Kingsbury ◽  
Jonathan P. Mochel ◽  
Todd Atherly ◽  
Lawrance C. Chandra ◽  
Rachel L. Phillips ◽  
...  

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