Personality profiles of patients with alcohol use disorder and opioid use disorder in an inpatient treatment setting

Psychopharmacology for Substance Use Disorders

10.2310/psych.13104 ◽

2021 ◽

Author(s):

Olapeju Simoyan ◽

Krista Ulisse

Keyword(s):

Substance Use ◽

Alcohol Use ◽

Alcohol Withdrawal ◽

Alcohol Use Disorder ◽

Maintenance Treatment ◽

The United States ◽

Opioid Use Disorder ◽

Opioid Use ◽

Duration Of Symptoms ◽

Stimulant Use

The illicit use of opioids is the fastest growing substance use problem in the United States. There are three FDA- approved medications for maintenance treatment for opioid use disorder: methadone, buprenorphine and naltrexone. Stimulants include cocaine and methamphetamines. 3,4-methylenedioxymethamphetamine (MDMA or “ecstasy”) is an amphetamine derivative that also has hallucinogenic properties. Treatment of stimulant withdrawal is primarily supportive. Psychosocial interventions for stimulant use disorder may improve adherence, but they have not been shown to improve abstinence at the end of treatment. Benzodiazepines have been shown to reduce the severity and duration of symptoms related to alcohol withdrawal, in addition to reducing the risk of seizures. The Food and Drug Administration has approved disulfiram, acamprosate and naltrexone for the treatment of alcohol use disorder. This review contains 3 tables, and 31 references. Keywords: Opioid use disorder, maintenance treatment for opioid use disorder, stimulant use disorder, stimulant withdrawal, benzodiazepine overdose, benzodiazepine withdrawal, alcohol use disorder, alcohol withdrawal

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Emergency department presentation of opioid use disorder and alcohol use disorder

Journal of Substance Abuse Treatment ◽

10.1016/j.jsat.2021.108343 ◽

2021 ◽

pp. 108343

Author(s):

Imam M. Xierali ◽

Philip G. Day ◽

Kurt C. Kleinschmidt ◽

Chance Strenth ◽

F. David Schneider ◽

...

Keyword(s):

Emergency Department ◽

Alcohol Use ◽

Alcohol Use Disorder ◽

Opioid Use Disorder ◽

Emergency Department Presentation ◽

Opioid Use

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Ambulatory detoxification in alcohol use disorder and opioid use disorder

Mental Health Clinician ◽

10.9740/mhc.2020.11.307 ◽

2020 ◽

Vol 10 (6) ◽

pp. 307-316

Author(s):

Troy A. Moore

Keyword(s):

Alcohol Use ◽

Alcohol Use Disorder ◽

Treatment Protocol ◽

Signs And Symptoms ◽

Opioid Use Disorder ◽

Vital Role ◽

Opioid Use ◽

Management Options ◽

Severe Withdrawal ◽

Appropriate Treatment

Abstract Ambulatory detoxification in alcohol use disorder and opioid use disorder is an important component in the management of patients experiencing withdrawal symptoms from alcohol or opioids. The goal of withdrawal management is ultimately to provide each patient with comfort and safety. Having the knowledge of the possible signs and symptoms of intoxication and withdrawal assists providers to institute the most appropriate treatment protocol and setting for the patient. Pharmacists play a vital role in choosing appropriate therapeutic management options for common or complex clinical situations involving ambulatory detoxification from alcohol and opioids. Ambulatory detoxification serves as an appealing option to many patients and helps save the limited inpatient resources that many institutions have for those patients with more severe withdrawal presentations.

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Adults with Comorbid Posttraumatic Stress Disorder, Alcohol Use Disorder, and Opioid Use Disorder: The Effectiveness of Modified Prolonged Exposure

Journal of Traumatic Stress ◽

10.1002/jts.22291 ◽

2018 ◽

Vol 31 (3) ◽

pp. 373-382 ◽

Cited By ~ 3

Author(s):

Kelly R. Peck ◽

Julie A. Schumacher ◽

Paul R. Stasiewicz ◽

Scott F. Coffey

Keyword(s):

Posttraumatic Stress Disorder ◽

Alcohol Use ◽

Posttraumatic Stress ◽

Alcohol Use Disorder ◽

Stress Disorder ◽

Prolonged Exposure ◽

Opioid Use Disorder ◽

Opioid Use

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P.0315 Association between hazardous alcohol use and initiation of naltrexone treatment for opioid use disorder among hiv-positive persons in russia

European Neuropsychopharmacology ◽

10.1016/j.euroneuro.2021.10.298 ◽

2021 ◽

Vol 53 ◽

pp. S228-S229

Author(s):

M. Vetrova ◽

E.A. Blokhina ◽

D.M. Cheng ◽

V. Truong ◽

E.K. Quinn ◽

...

Keyword(s):

Alcohol Use ◽

Opioid Use Disorder ◽

Hiv Positive ◽

Opioid Use ◽

Hazardous Alcohol Use ◽

Hazardous Alcohol ◽

Naltrexone Treatment

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Dual diagnosis inpatient treatment outcomes for individuals with co-occurring chronic pain and opioid use disorder

Journal of Pain ◽

10.1016/j.jpain.2017.12.082 ◽

2018 ◽

Vol 19 (3) ◽

pp. S32

Author(s):

C. Cutter ◽

F. Buono ◽

S. Ackerman ◽

M. Brennan ◽

D. Mueller ◽

...

Keyword(s):

Chronic Pain ◽

Treatment Outcomes ◽

Dual Diagnosis ◽

Inpatient Treatment ◽

Opioid Use Disorder ◽

Opioid Use

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Validity and Reliability of the Computer-Administered Routine Opioid Outcome Monitoring (ROOM) Tool

Pain Medicine ◽

10.1093/pm/pnaa297 ◽

2020 ◽

Vol 21 (12) ◽

pp. 3645-3654

Author(s):

Louisa Picco ◽

Melissa Middleton ◽

Raimondo Bruno ◽

Michala Kowalski ◽

Suzanne Nielsen

Keyword(s):

Alcohol Use ◽

Pearson Correlation ◽

Correlation Coefficients ◽

Opioid Use Disorder ◽

Opioid Use ◽

Chronic Noncancer Pain ◽

Retest Reliability ◽

Outcome Monitoring ◽

Test Retest Reliability ◽

Over Time

Abstract Objective The Routine Opioid Outcome Monitoring (ROOM) tool measures outcomes with opioids using an established framework which includes domains such as pain, mood, opioid use disorder, alcohol use, and constipation. This study aims to validate and establish the test-retest reliability of the computer-administered ROOM tool. Design and Setting Cross-sectional analysis of an online sample. Subjects Participants comprised those with chronic noncancer pain who regularly used prescription opioids. Methods Participants self-completed the online ROOM tool along with other validated measures (validation questionnaire), and those who were agreeable also completed the online test-retest questionnaire approximately two weeks later. Subcomponents of the ROOM tool (i.e., pain, mood, alcohol use, opioid use disorder, and constipation) were validated against longer measures of the same construct using Pearson correlation coefficients. Intraclass correlation coefficients were used to assess the stability of the ROOM tool over time. Results A total of 324 participants completed the validation questionnaire, of whom 260 also completed the test-retest questionnaire. The opioid use disorder domain showed good sensitivity (73.6) and specificity (75.8) against the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition, any opioid use disorder. All ROOM components showed moderate correlation (r = 0.55–0.73) with their longer counterparts. Test-retest reliability was fair (0.58–0.75), indicating that responses were relatively stable over time. Reliability did vary, however, based on the components being measured and how certain tools were scored. Conclusion The computer-administered ROOM tool is a valid approach for brief monitoring of outcomes with prescribed opioids in primary care settings and appears to be acceptable to people who are using prescribed opioids for chronic pain.

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P.443 Does alcohol use provoke relapse in patients with opioid use disorder stabilized on naltrexone?

European Neuropsychopharmacology ◽

10.1016/j.euroneuro.2019.09.455 ◽

2019 ◽

Vol 29 ◽

pp. S314

Author(s):

V. Palatkin ◽

E. Krupitsky ◽

E. Blokhina ◽

E. Verbitskaya ◽

E. Zvartau ◽

...

Keyword(s):

Alcohol Use ◽

Opioid Use Disorder ◽

Opioid Use

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Prevalence of marijuana use in pregnant women with concurrent opioid use disorder or alcohol use in pregnancy

Addiction Science & Clinical Practice ◽

10.1186/s13722-021-00285-z ◽

2022 ◽

Vol 17 (1) ◽

Author(s):

Kimberly Page ◽

Cristina Murray-Krezan ◽

Lawrence Leeman ◽

Mary Carmody ◽

Julia M. Stephen ◽

...

Keyword(s):

Alcohol Use ◽

Pregnant Women ◽

Maternal Age ◽

Alcohol Exposure ◽

Marijuana Use ◽

Opioid Use Disorder ◽

Opioid Use ◽

Alcohol Group ◽

Lower Odds ◽

In Pregnancy

Abstract Background A quarter of pregnant women use alcohol, 6.5/1000 deliveries are affected by opioid use disorder (OUD), and the prevalence of cannabis use in pregnant women is increasing. However, marijuana co-exposure in polysubstance-using women is not well described. Methods The well-characterized ENRICH-1 cohort (n = 251), which focused on the effects of two primary exposures of interest—opioids and alcohol, was used to (1) estimate the prevalence/frequency of marijuana use in those with OUD and/or alcohol use, and (2) examined correlates of marijuana use. Participants were classified into an OUD group (n = 125), Alcohol group (n = 69), and concurrent OUD and Alcohol (OUD + Alcohol) group (n = 57). Self-report and biomarkers ascertained substance use. Multivariable logistic regression identified correlates of marijuana use. Results The prevalence of any marijuana use in pregnancy was 43.2%, 52.6%, and 46.4% in the OUD, OUD + Alcohol, and Alcohol groups, respectively. Correspondingly, weekly or daily use was reported by 19.4%, 21.0%, and 24.6% of participants. In the OUD and OUD + Alcohol groups, the proportion of women using marijuana was significantly higher in those taking buprenorphine (45.8% and 58.3%, respectively) compared to women using methadone (37.5% and 42.9%, respectively). Mean maternal age was lower in women who used marijuana in all three groups compared to non-marijuana users. Independent correlates of marijuana use (controlling for group, race/ethnicity, education, and smoking) were maternal age (adjusted Odds Ratio (aOR) per 5-year increment 0.61; (95% CI 0.47, 0.79)), and polysubstance use (aOR 2.02; 95% CI 1.11, 3.67). There was a significant interaction between partnership status and group: among women who were not in a partnership, those in the OUD and OUD + Alcohol groups had lower odds of marijuana use relative to the Alcohol group. For women in the Alcohol group, partnered women had lower odds of marijuana use than un-partnered women (aOR 0.12; 95% CI: 0.02, 0.68). Conclusions Results indicate a relatively high prevalence and frequency of marijuana use in pregnant women being treated for OUD and/or women consuming alcohol while pregnant. These results highlight the need for ongoing risk reduction strategies addressing marijuana use for pregnant women receiving OUD treatment and those with alcohol exposure.

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