scholarly journals Base on concept of traditional Chinese medicine: Experimental studies on efficacy of BIOCERAMIC Resonance to alleviate drug withdrawal symptoms

2019 ◽  
Vol 9 (4) ◽  
pp. 257-262 ◽  
Author(s):  
Ting Kai Leung ◽  
Chi Ming Lee ◽  
Mimmo Gasbarri ◽  
Yung Che Chen
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Drug Withdrawal ◽  
Experimental Studies ◽  
Withdrawal Symptoms

scholarly journals The Anti-Neuroinflammatory Effect of Fuzi and Ganjiang Extraction on LPS-Induced BV2 Microglia and Its Intervention Function on Depression-Like Behavior of Cancer-Related Fatigue Model Mice

2021 ◽  
Vol 12 ◽  
Author(s):  
Songwei Yang ◽  
Yantao Yang ◽  
Cong Chen ◽  
Huiqin Wang ◽  
Qidi Ai ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Inflammatory Mediators ◽  
Critical Role ◽  
Chinese Herb ◽  
Experimental Studies ◽  
Research Results ◽  
Cancer Related Fatigue

The Chinese herb couple Fuzi and Ganjiang (FG) has been a classic combination of traditional Chinese medicine that is commonly used clinically in China for nearly 2000 years. Traditional Chinese medicine suggests that FG can treat various ailments, including heart failure, fatigue, gastrointestinal upset, and depression. Neuroinflammation is one of the main pathogenesis of many neurodegenerative diseases in which microglia cells play a critical role in the occurrence and development of neuroinflammation. FG has been clinically proven to have an efficient therapeutic effect on depression and other neurological disorders, but its mechanism remains unknown. Cancer-related fatigue (CRF) is a serious threat to the quality of life of cancer patients and is characterized by both physical and psychological fatigue. Recent studies have found that neuroinflammation is a key inducement leading to the occurrence and development of CRF. Traditional Chinese medicine theory believes that extreme fatigue and depressive symptoms of CRF are related to Yang deficiency, and the application of Yang tonic drugs such as Fuzi and Ganjiang can relieve CRF symptoms, but the underlying mechanisms remain unknown. In order to define whether FG can inhibit CRF depression-like behavior by suppressing neuroinflammation, we conducted a series of experimental studies in vitro and in vivo. According to the UPLC-Q-TOF/MSE results, we speculated that there were 49 compounds in the FG extraction, among which 30 compounds were derived from Fuzi and 19 compounds were derived from Ganjiang. Our research data showed that FG can effectively reduce the production of pro-inflammatory mediators IL-6, TNF-α, ROS, NO, and PGE2 and suppress the expression of iNOS and COX2, which were related to the inhibition of NF-κB/activation of Nrf2/HO-1 signaling pathways. In addition, our research results revealed that FG can improve the depression-like behavior performance of CRF model mice in the tail suspension test, open field test, elevated plus maze test, and forced swimming test, which were associated with the inhibition of the expression of inflammatory mediators iNOS and COX2 in the prefrontal cortex and hippocampus of CRF model mice. Those research results suggested that FG has a satisfactory effect on depression-like behavior of CRF, which was related to the inhibition of neuroinflammation.

scholarly journals The Influence of Pc6 on Cardiovascular Disorders: A Review of Central Neural Mechanisms

2012 ◽  
Vol 30 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Jia Li ◽  
Jing Li ◽  
Zebin Chen ◽  
Fengxia Liang ◽  
Song Wu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Arcuate Nucleus ◽  
Experimental Studies ◽  
Acupuncture Point ◽  
Neural Mechanisms ◽  
Ventrolateral Medulla ◽  
Cardiovascular Disorders ◽  
Reflex Responses ◽  
Cardiovascular Reflex

PC6 is a classic acupuncture point in traditional Chinese medicine. It is considered to be effective when treating cardiovascular disorders. In the present review the authors have focused on the neurophysiological bases of the effects of PC6 stimulation on cardiovascular mechanisms. Experimental studies have shown that the hypothalamic rostral ventrolateral medulla, arcuate nucleus and ventrolateral periaqueductal gray are involved in acupuncture attenuation of sympathoexcitatory cardiovascular reflex responses. This long-loop pathway also appears to contribute to the long-lasting, acupuncture-mediated attenuation of sympathetic premotor outflow and excitatory cardiovascular reflex responses. Acupuncture of PC6 modulates the activity in the cardiovascular system, an effect that may be attributed to attenuation of sympathoexcitatory cardiovascular reflex responses.

scholarly journals A Disturbance Rejection Framework for the Study of Traditional Chinese Medicine

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Han Zhang ◽  
Yan Sun ◽  
Zhiqiang Gao ◽  
Yueqi Wang
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Disturbance Rejection ◽  
Experimental Studies ◽  
Engineering Science ◽  
Cybernetic Model ◽  
Cancer Pathogenesis ◽  
History Of ◽  
Engineering Concept

The traditional Chinese medicine (TCM) is explained in the language of engineering cybernetics (EC), an engineering science with the tradition of rigor and long history of practice. The inherent connection is articulated between EC, as a science of interrelations, and the Chinese conception of Wuxing. The combined cybernetic model of Wuxing seems to have significant explaining power for the TCM and could potentially facilitate better communications of the insights of the TCM to the West. In disturbance rejection, an engineering concept, a great metaphor, is found to show how the TCM is practiced, using the liver cancer pathogenesis and treatment as a case study. The results from a series of experimental studies seem to lend support to the cybernetic model of Wuxing and the principles of disturbance rejection.

Antioxidant Effect of Tianwang Buxin Pills A Traditional Chinese Medicine Formula: Double-Blind, Randomized Controlled Trial

2009 ◽  
Vol 37 (02) ◽  
pp. 227-239 ◽  
Author(s):  
Gyeong Taek Gim ◽  
Hyung-Min Kim ◽  
Jiyoung Kim ◽  
Jongwoo Kim ◽  
Wei-Wan Whang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Controlled Trial ◽  
Experimental Studies ◽  
Reactive Oxygen ◽  
Reactive Oxygen Metabolites ◽  
Double Blind ◽  
Ischemic Disease ◽  
Randomized Controlled ◽  
Quality Of Life Scale

Reactive oxygen species (ROS) and their derivatives play important roles in the development of diseases such as, cardiovascular disease, ischemic disease, and aging. Much effort has been devoted to finding both an effective and non-toxic antioxidant traditional Chinese medicine (TCM) herbal formula. Tianwang Buxin Pills (TBPs) have been used in TCM to treat mild cognitive impairment and palpitations. Recently, research has revealed that TBPs are effective against oxidative stress and psychological stress in experimental studies. However, randomized controlled trials (RCT) are rare. This study was conducted to assess the antioxidative and anti-stress effects of TBPs by analyzing (determination) reactive oxygen metabolites (d-ROMs test) of the blood, the stress response inventory (SRI), and the Korean version of the WHO Quality of Life Scale Abbreviated Version (WHOQOL-BREF) in 39 healthy volunteers (Placebo group = 20, TBPs group = 19) before and after oral administration of TBPs for 4 weeks. However, d-ROMs test, SRI, and WHOQOL-BREF values did not differ significantly between the two groups. These results indicate that TBPs do not effectively restrain ROS or their derivatives.

scholarly journals Application of Traditional Chinese Medicine in Treatment of Atrial Fibrillation

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Yan Dong ◽  
Jiangquan Liao ◽  
Kuiwu Yao ◽  
Wenrui Jiang ◽  
Jie Wang
Keyword(s):  
Atrial Fibrillation ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Tai Chi ◽  
Experimental Studies ◽  
Herbal Medicines ◽  
Treatment Strategies ◽  
The Elderly ◽  
High Recurrence Rate ◽  
Bioactive Ingredients

Atrial fibrillation (AF) is the most common cardiac arrhythmia, which is related to many cardiac and cerebral vascular diseases, especially stroke. It can therefore increase cardiovascular mortality and all-cause death. The current treatments of AF remain to be western drugs and radiofrequency ablation which are limited by the tolerance of patients, adverse side effects, and high recurrence rate, especially for the elderly. On the contrary, traditional Chinese medicine (TCM) with long history of use involves various treatment methods, including Chinese herbal medicines (CHMs) or bioactive ingredients, Chinese patent medicines, acupuncture, Qigong, and Tai Chi Chuan. With more and more researches reported, the active roles of TCM in AF management have been discovered. Then it is likely that TCM would be effective preventive means and valuable additional remedy for AF. The potential mechanisms further found by numerous experimental studies showed the distinct characteristics of TCM. Some CHMs or bioactive ingredients are atrial-selective, while others are multichannel and multifunctional. Therefore, in this review we summarized the treatment strategies reported in TCM, with the purpose of providing novel ideas and directions for AF management.

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