scholarly journals Antibacterial oral sprays from kaffir lime (Citrus hystrix DC.) fruit peel oil and leaf oil and their activities against respiratory tract pathogens

2020 ◽  
Vol 10 (6) ◽  
pp. 594-598 ◽  
Author(s):  
Somporn Srifuengfung ◽  
Nuntavan Bunyapraphatsara ◽  
Veena Satitpatipan ◽  
Chanwit Tribuddharat ◽  
Varaporn Buraphacheep Junyaprasert ◽  
...  
Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3387
Author(s):  
Gugulethu Miya ◽  
Mongikazi Nyalambisa ◽  
Opeoluwa Oyedeji ◽  
Mavuto Gondwe ◽  
Adebola Oyedeji

The medicinal potential and volatile composition of different parts of three cultivars of grapefruit (Citrus paradisi) were evaluated for their toxicity and anti-inflammatory activities. Fresh leaf and fruit peel were separately isolated by hydrodistillation for 4 h. The essential oils were subjected to GC/GC-MS analysis for chemical profile. Toxicity of the essential oils in mice were evaluated using Lorke’s method, while an anti-inflammatory assay was performed in a rat model using egg albumin-induced oedema. The oils obtained were light yellow in colour, and odour varied from strong citrus smell to mild. Percentage yield of fresh peel oil (0.34–0.57%) was greater than the fresh leaf oil yield (0.21–0.34%). D-limonene (86.70–89.90%) was the major compound identified in the leaf oil, while β-phellandrene (90.00–91.01%) dominated the peel oil. At a dosage level of 5000 mg/kg, none of the oils showed mortality in mice. An anti-inflammatory bioassay revealed that all the oils caused a significant (p < 0.05–0.01) reduction in oedema size when compared to the negative control group throughout the 5 h post induction assessment period. The study reveals that the oils are non-toxic and demonstrate significant anti-inflammatory activity. Our findings suggest that the leaf and peel oils obtained from waste parts of grapefruit plants can be useful as flavouring agents, as well as anti-inflammatory agents.


2009 ◽  
Vol 1 (2) ◽  
pp. 387-392 ◽  
Author(s):  
M. N. I. Bhuiyan ◽  
J. Begum ◽  
P. K. Sardar ◽  
M. S. Rahman

The chemical constituents of leaf and peel essential oil of Citrus medica L. were analysed by gas chromatography mass spectroscopy (GC-MS). Nineteen components accounting for 99.9% of the oil were identified in leaf oil. The major constituents are erucylamide (28.43%), limonene (18.36%) and citral (12.95%). The peel oil contains forty three components accounting for 99.8% of the total oil and the major components are isolimonene (39.37%), citral (23.12%) and limonene (21.78%). Keywords: Citrus medica; Essential oils; GC-MS; Erucylamide; Isolimonene. © 2009 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.DOI: 10.3329/jsr.v1i2.1760   


Medicines ◽  
2017 ◽  
Vol 4 (1) ◽  
pp. 1 ◽  
Author(s):  
Gang Deng ◽  
Jonathan Craft ◽  
Kelly Steinberg ◽  
Pei Li ◽  
Suraj Pokharel ◽  
...  

1996 ◽  
Vol 8 (4) ◽  
pp. 415-416 ◽  
Author(s):  
Nguyêñ Manh Pha ◽  
Vũ Ngoc Lô ◽  
Nguyêñ Xuân Dũng ◽  
Piet A. Leclercq
Keyword(s):  

1999 ◽  
Vol 26 (1) ◽  
pp. 13-17 ◽  
Author(s):  
R. T. Awuah

Abstract Products from five medicinal/culinary plants—Citrus aurantifolia fruit peel oil, Cymbopogon nardus leaf oil, Ocimum gratissimum leaf powder, Xylopia aethiopica fruit powder, and Syzigium aromaticum clove powder—were tested for activity against fungal colonization of stored peanut. The natural microflora of kernels were supplemented with a norsolorinic acid (NOR) mutant of Aspergillus parasiticus before treatment with the various plant products. Treated kernels were stored at 5.7% moisture content in mini-polyethylene bags for 11 mo. Of the five plant products, the Syzigium clove powder proved to be most efficacious. After 4 mo storage, a low colony-forming unit (CFU) value of 0.601 log units of NOR A. parasiticus was recorded per gram of kernels treated with the powder. Significantly higher CFU values (P ≤ 0.05) were associated with kernels that received no plant product (3.099 log units) and kernels treated with the other plant products(1.459–2.930 log units). CFU of total fungi, superficial fungal growth, internal kernel discoloration, and fungal growth/sporulation on the internal surfaces of the cotyledons also were suppressed by the Syzigium powder after 11 mo. The Citrus oil and the Ocimum leaf powder were moderately effective, being similar to each other in several storage parameters. The Cymbopogon leaf oil was the least effective of the plant materials tested. In a test tube experiment, the Syzigium and Ocimum powders were more efficacious when mixed with stored peanut kernels than when separated from kernels with a piece of mosquito-proof screen. The optimum rates of the two powders for preventing superficial fungal growth on kernels at 8% moisture in mini-polyethylene bags at 28 C were 150 and 100 g/kg of kernels, respectively, for Syzigium and Ocimum. At these rates, 93 and 56% of kernels treated with the Syzigium and Ocimum powders, respectively, were free from superficial fungal growth after 4 mo. These results point to the potential of the two powders, especially Syzigium, for preventing mold growth and possibly aflatoxin production in stored peanut.


1996 ◽  
Vol 8 (1) ◽  
pp. 15-18 ◽  
Author(s):  
Nguyêñ Xuân Dũng ◽  
Nguyêñ Manh Pha ◽  
Vũ Ngoc Lô ◽  
Nguyêñ Huũ Thiên ◽  
Piet A. Leclercq

1999 ◽  
Vol 11 (5) ◽  
pp. 629-632 ◽  
Author(s):  
Ajit K. Bordoloi ◽  
Madan G. Pathak ◽  
Jaroslava Sperkova ◽  
Piet A. Leclercq

2013 ◽  
Vol 68 (7-8) ◽  
pp. 275-284 ◽  
Author(s):  
Dalia Hamdan ◽  
Mohamed L. Ashour ◽  
Sri Mulyaningsih ◽  
Assem El-Shazly ◽  
Michael Wink

The volatile secondary metabolites of essential oils from fruit peel and leaves of variegated pink-fl eshed lemon (Citrus x limon) were investigated using GLC and GLC-MS (gas-liquid chromatography-mass spectroscopy). Altogether 141 compounds were identified and quantified, accounting for 99.59% and 96.33% of the total hydrodistilled peel and leaf oil, respectively. Limonene occurred in higher amounts in fruit peel (52.73%) than in leaf oil (29.13%). Neral (12.72%), neryl acetate (8.53%), ρ-menth-1-en-7-al (4.63%), β-pinene (6.35%), and nerol (4.42%) were the most abundant constituents in leaf oil, whereas γ-terpinene (9.88%), β-pinene (7.67%), geranial (4.44%), and neral (3.64%) dominated in the fruit peel oil. The antioxidant, anti-inflammatory, antitrypanosomal, and antimicrobial activities of the fruit peel essential oil were evaluated. The oil had a low antioxidant activity with an IC50 value of (26.66 ± 2.07) mg/ml as compared to the efficient antioxidant ascorbic acid [IC50 (16.32 ± 0.16) μg/ml]. The oil moderately inhibited soybean 5-lipoxygenase (5-LOX) with an IC50 value of (32.05 ± 3.91) μg/ml and had moderate antitrypanosomal activity [IC50 (60.90 ± 0.91) μg/ml]. In addition, moderate antimicrobial activities were detected against Gram-positive bacteria (Bacillus subtilis, Staphylococcus capitis, Micrococcus luteus), one Gram-negative bacterium (Pseudomonas fluorescens), and yeasts (Saccharomyces cerevisiae, Candida parapsilosis)


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