Secreted Ly-6/uPAR-related protein-1 (SLURP1) is a pro-differentiation factor that stalls G1-S transition during corneal epithelial cell cycle progression

2021 ◽  
Author(s):  
Sudha Swamynathan ◽  
Gregory Campbell ◽  
Anil Tiwari ◽  
Shivalingappa K. Swamynathan
Keyword(s):  
Cell Cycle ◽  
Epithelial Cell ◽  
Cell Cycle Progression ◽  
Corneal Epithelial Cell ◽  
Related Protein ◽  
Cycle Progression ◽  
Corneal Epithelial ◽  
Differentiation Factor

scholarly journals Lactobacillus Decelerates Cervical Epithelial Cell Cycle Progression

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e63592 ◽  
Author(s):  
Katarina Vielfort ◽  
Linda Weyler ◽  
Niklas Söderholm ◽  
Mattias Engelbrecht ◽  
Sonja Löfmark ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Epithelial Cell ◽  
Cell Cycle Progression ◽  
Cycle Progression ◽  
Cervical Epithelial Cell

scholarly journals Regulation ofBRCA1messenger RNA stability in human epithelial cell lines and during cell cycle progression

FEBS Letters ◽  
2007 ◽  
Vol 581 (18) ◽  
pp. 3435-3442 ◽  
Author(s):  
Jodi M. Saunus ◽  
Stacey L. Edwards ◽  
Juliet D. French ◽  
Chanel E. Smart ◽  
Melissa A. Brown
Keyword(s):  
Cell Cycle ◽  
Epithelial Cell ◽  
Cell Lines ◽  
Cell Cycle Progression ◽  
Rna Stability ◽  
Human Epithelial Cell ◽  
Cycle Progression ◽  
Epithelial Cell Lines

La-related protein 4B maintains murine MLL-AF9 leukemia stem cell self-renewal by regulating cell cycle progression

2015 ◽  
Vol 43 (4) ◽  
pp. 309-318.e2 ◽  
Author(s):  
Yingchi Zhang ◽  
Luyun Peng ◽  
Tianyuan Hu ◽  
Yang Wan ◽  
Yuanyuan Ren ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Stem Cell ◽  
Cell Cycle Progression ◽  
Related Protein ◽  
Self Renewal ◽  
Cycle Progression ◽  
Leukemia Stem Cell

scholarly journals Idas, a Novel Phylogenetically Conserved Geminin-related Protein, Binds to Geminin and Is Required for Cell Cycle Progression

2011 ◽  
Vol 286 (26) ◽  
pp. 23234-23246 ◽  
Author(s):  
Dafni-Eleutheria Pefani ◽  
Maria Dimaki ◽  
Magda Spella ◽  
Nickolas Karantzelis ◽  
Eirini Mitsiki ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Progression ◽  
Related Protein ◽  
Cycle Progression

scholarly journals On–off switching of cell cycle and melanogenesis regulation of melanocytes by non-thermal atmospheric pressure plasma-activated medium

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Jin-Woo Lee ◽  
Se Jik Han ◽  
Hye Young Kang ◽  
Sung-Suk Wi ◽  
Min-Hyung Jung ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Atmospheric Pressure ◽  
Cell Cycle Progression ◽  
Growth Promotion ◽  
Atmospheric Pressure Plasma ◽  
Related Protein ◽  
Normal Human Skin ◽  
Cycle Progression ◽  
Short Period ◽  
Tyrosinase Related Protein

Abstract Non-thermal atmospheric pressure (NAP) plasma has demonstrated potential in biomedical applications, such as cancer treatment, bactericidal sterilization, and cell growth promotion or inhibition. In this study, for the first time, we demonstrated on–off switching of cell cycle progression and regulated melanogenesis in normal human skin melanocytes by NAP plasma-activated medium (PAM). The melanocytes were exposed to NAP plasma at durations varying from 0 to 20 min, and the effects of PAM on cell proliferation, cell cycle progression, and melanogenesis were investigated. Although PAM showed no cytotoxicity, the proliferation of melanocytes was inhibited. The melanocyte cell cycle was arrested by PAM for a relatively short period (48 h), after which it recovered slowly. PAM promoted melanogenesis through the activation of the enzymes tyrosinase, tyrosinase-related protein-1, and tyrosinase-related protein-2. These effects seem to be related to reactive oxygen species induced by PAM. Our finding that PAM modulates the cell cycle may provide insight into the recurrence of cancer. The regulation of the melanogenesis of melanocytes may facilitate the control of skin tone without incurring negative side effects.

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