Reservoir Alternate Surgical Implantation Technique: Preliminary Outcomes of Initial PROPPER Study of Low Profile or Spherical Reservoir Implantation in Submuscular Location or Traditional Prevesical Space

2015 ◽  
Vol 193 (1) ◽  
pp. 239-244 ◽  
Author(s):  
Edward Karpman ◽  
William O. Brant ◽  
Bryan Kansas ◽  
Anthony J. Bella ◽  
LeRoy A. Jones ◽  
...  
Author(s):  
Humberto Dória Silva ◽  
Rostan Silvestre da Silva ◽  
Eduardo Dória Silva ◽  
Maria Tamires Dória Silva ◽  
Cristiana Pereira Dória ◽  
...  

Neurophysiological anatomy of natural binocular vision shows the need to focus with both eyes to jointly produce the two corneas accommodation, correcting, in a compensatory way, the divergences inherent in the two different images, of the same visual field projected in the two distinct spaces, the two retinas. Corneal accommodation is part of the forced convection mechanism for the transfer of mobile mass in the cornea, trabecular meshwork and retina, to inhibit the accumulation of dehydrated intraocular metabolic residue, which can cause refractive errors in the cornea, obstruction of the trabecular meshwork and reduction of the amplitude of the signals produced by the phototransducers and sent to the brain. The IOL monovision surgical implantation technique differs from the physiology of natural binocular vision, which can cause after surgery disorders, described in this chapter, in that it imposes a different adaptation from the neurophysiological anatomy of human vision in addition to favoring the continuous progression of residue accumulation dehydrated intraocular metabolic and stimulate ocular.


2016 ◽  
Vol 45 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Valentine Martlé ◽  
Luc M. L. Van Ham ◽  
Paul Boon ◽  
Jacques Caemaert ◽  
Mulenda Tshamala ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Maria Xeroudaki ◽  
Muthukumar Thangavelu ◽  
Anton Lennikov ◽  
Anjula Ratnayake ◽  
Jovana Bisevac ◽  
...  

Abstract Biomaterials designed to replace the diseased cornea could be used to treat corneal blindness where human donor tissue is in short supply, but challenges are the integration of biomaterials with host tissue and cells, avoiding a rapid material degradation and maintaining corneal transparency. Additionally, implantation surgery often triggers an aggressive wound healing response that can lead to corneal thinning and opacity. Here, we report a collagen-based hydrogel with transparency and mechanical properties suitable for replacing a substantial portion of a damaged or diseased corneal stroma. The porous hydrogel permitted migration and population by host cells while maintaining transparency and thickness six months after surgical implantation in an in vivo model of human corneal surgery. With a novel hybrid surgical implantation technique inspired by LASIK refractive surgery, rapid wound healing occurred around implants to maintain biomaterial integrity, transparency and function. Host stromal cell repopulation and regeneration of host epithelium and nerves were observed, as necessary steps towards corneal regeneration. Finally, as a proof-of-principle, the hydrogel loaded with a neuroregenerative drug achieved sustained slow-release drug delivery in vitro. The proposed hydrogel and novel implantation technique together represent a therapeutic approach with translational potential for replacing and regenerating diseased corneal stromal tissue.


2007 ◽  
Vol 177 (4S) ◽  
pp. 62-63
Author(s):  
Oleg Sukonko ◽  
Sergey Krasny ◽  
Sergey Polaykov ◽  
Alexandr Rolevich ◽  
Carsten H. Ohlmann ◽  
...  

Author(s):  
J Wiskirchen ◽  
K Brechtel ◽  
A Fischmann ◽  
G Tepe ◽  
S Miller ◽  
...  
Keyword(s):  

2010 ◽  
Vol 5 (1) ◽  
pp. 20 ◽  
Author(s):  
Tim A Fischell ◽  

Coronary artery stenting has evolved substantially since the first use of coronary stenting as an adjunct to balloon angioplasty in the early 1990s. The performance (and particularly the deliverability) of coronary stents has improved such that coronary stenting is now the primary mode of revascularisation for percutaneous coronary interventions (PCIs) in more than 95% of cases. The new Svelte™ stent-on-a-wire (SOAW) delivery system represents one of the first substantive innovations in stent delivery systems (SDS) in more than a decade. This SDS uses a shapeable ‘fixed wire’ as an integral part of the SDS. This allows a significant reduction in SDS profile (~0.029 inches) compared with conventional monorail or over-the-wire SDS. This SOAW SDS is intended to facilitate direct stenting. It has the potential to provide substantial procedural cost savings by eliminating the need for a coronary guidewire and balloon pre-dilatation and/or post-dilatation, and by reducing contrast use and the time required to complete the procedure. The SOAW system is compatible with 5Fr guiding catheters, and may reduce the need for closure devices, facilitate stenting via the radial approach and (potentially) reduce bleeding risks. In conclusion, the Svelte SOAW SDS represents a new very-low-profile balloon-expandable SDS that should promote direct stenting in PCIs. The efficiency and small profile of this SDS may allow procedural cost savings, a reduction in procedure time and a reduced risk of bleeding complications. These theoretical advantages will need to be demonstrated in clinical trials.


2010 ◽  
Vol E93-B (10) ◽  
pp. 2570-2577 ◽  
Author(s):  
Daisuke UCHIDA ◽  
Hiroyuki ARAI ◽  
Yuki INOUE ◽  
Keizo CHO

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