scholarly journals Access To The Procedure Care of Colorectal Cancer In Brazilian Public Health System: Use Of Diagnosis Resources In São Paulo State

2015 ◽  
Vol 18 (7) ◽  
pp. A805
Author(s):  
D Oliveira ◽  
A Luque ◽  
SM Junqueira Junior ◽  
FM Oliveira ◽  
HA Cabra
Keyword(s):  
Public Health ◽  
Colorectal Cancer ◽  
Health System ◽  
Public Health System ◽  
Sao Paulo ◽  
São Paulo ◽  
Paulo State ◽  
System Use ◽  
São Paulo State

scholarly journals Evolution of bacterial meningitis diagnosis in Sao Paulo State-Brazil and future challenges

2013 ◽  
Vol 71 (9B) ◽  
pp. 672-676 ◽  
Author(s):  
Maristela Marques Salgado ◽  
Maria Gisele Goncalves ◽  
Lucila Okuyama Fukasawa ◽  
Fabio Takenori Higa ◽  
Juliana Thalita Paulino ◽  
...  
Keyword(s):  
Public Health ◽  
Bacterial Meningitis ◽  
Public Health Problem ◽  
Sao Paulo ◽  
Immunological Methods ◽  
Haemophilus Influenzae Type ◽  
Molecular Technique ◽  
São Paulo ◽  
Paulo State ◽  
São Paulo State

Bacterial meningitis (BM) is a severe disease and still represents a serious public health problem with high rates of morbidity and mortality. The most common cases of BM around the world, mainly in Brazil, have been caused by Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae type b. Bacterial culture is the gold-standard technique for BM confirmation, but approximately 50% of suspected cases are not culture-confirmed, due to problems related to improper transportation and seeding or previous antibiotic treatment. Immunological methods present low sensitivity and have possibility of cross-reactions. Real time PCR (qPCR) is a molecular technique and has been successful used for BM diagnosis at Instituto Adolfo Lutz in São Paulo State, Brazil, since 2007. The incorporation of qPCR in the Public Health surveillance routine in our state resulted in diminishing 50% of undetermined BM cases. Our efforts are focused on qPCR implementation in the BM diagnostic routine throughout Brazil.

scholarly journals Clinical, Epidemiological, and Geospatial Characteristics of Patients Infected with Hepatitis C Virus Treated with Second-Generation Direct-Action Antivirals in a Reference Center in a Mesoregion of São Paulo State, Brazil

2020 ◽  
Vol 8 (10) ◽  
pp. 1575
Author(s):  
Danilo Zangirolami Pena ◽  
Murilo Fernandes Anadão ◽  
Edilson Ferreira Flores ◽  
Mayara Namimatsu Okada ◽  
Alexandre Martins Portelinha Filho ◽  
...  
Keyword(s):  
Public Health ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Health System ◽  
Second Generation ◽  
Direct Action ◽  
Sao Paulo ◽  
Reference Center ◽  
Paulo State ◽  
São Paulo State

Hepatitis virus infection is a major public health problem worldwide. Currently, Brazil has almost 700,000 cases. The Brazilian Unified Health System (SUS) provides therapeutic regimens for people infected with hepatitis C virus (HCV). We determined the clinical, laboratory, epidemiologic, and geospatial characteristics of patients infected with HCV treated with second-generation direct-action antivirals (DAAs) in a hospital reference center in São Paulo state, Brazil, using data from file records. A map was constructed using a geographic information system. From 2015 to 2018, 197 individuals received second-generation DAAs (mean age, 57.68 ± 1.36 years; interquartile range, 56.22–59.14 years; 58.9% male; 41.1% female). Genotypes 1a and 1b accounted for 75.7% of cases and the prevalent therapeutic regimen was sofosbuvir/simeprevir. Sustained viral response accounted for 98.9% and the METAVIR score F3/F4 for 50.8%. Increased alanine transferase was significantly correlated with an increase in α-fetoproteins (p = 0.01), and severe necro-inflammatory activity (p = 0.001). Associated comorbidities were found in 71.6%, mainly coronary artery and gastrointestinal disorders. The cumulative incidence in the region was 2.6 per 10,000 inhabitants. Our data highlight the role of reference hospitals in Brazil’s public health system in the treatment of HCV. Low incidence rates demonstrated the fragility of municipalities in the active search for patients.

Giardia and Cryptosporidium in source waters of Sao Paulo State, Brazil

2004 ◽  
Vol 50 (1) ◽  
pp. 239-245 ◽  
Author(s):  
E.M. Hachich ◽  
M.I.Z. Sato ◽  
A.T. Galvani ◽  
J.R.N. Menegon ◽  
J.L.N. Mucci
Keyword(s):  
Public Health ◽  
Drinking Water ◽  
Intestinal Parasites ◽  
Rank Correlation ◽  
Disease Outbreaks ◽  
Sao Paulo ◽  
Immunofluorescence Assay ◽  
São Paulo ◽  
Paulo State ◽  
São Paulo State

Giardia lamblia and Cryptosporidium parvum are two protozoan intestinal parasites responsible for many drinking-water-related disease outbreaks in recent years. They are very resistant to conventional water treatment processes, can persist for long times in the environment and are, therefore, of great concern for public health. This work aimed to evaluate the presence of Giardia and Cryptosporidium in water sources from São Paulo State, Brazil, as part of the “Evaluation of Inland Waters from Sao Paulo State” project from CETESB. Over a period of 19 months, 278 water samples from 28 sites located in 10 watersheds were analysed. The immunofluorescence assay was used after concentration of the samples by the calcium carbonate flocculation technique. Thermotolerant (faecal) coliforms, faecal streptococci and Clostridium perfringens were also determined in order to verify the existence of correlation between these bacterial indicators and the protozoa. Giardia and Cryptosporidium were detected in 27% and 2.5% of the samples, respectively, a lower figure compared with the results reported by other authors, especially for Cryptosporidium. A Spearman rank correlation test demonstrated a significant correlation between Giardia and faecal indicator concentrations. According to the American Regulation of Monitoring (ICR), treated water from 16 of these 28 collection sites should also be analysed to evaluate whether the treatment process could remove the parasites. Some technical deficiencies of these methods still limit the utilisation of the monitoring results for public health decisions, but the data here reported will help to improve the quality of drinking water in Sao Paulo State.

scholarly journals The Importance of Coordinated Actions in Preventing the Spread of Yellow Fever to Human Populations: The Experience from the 2016-2017 Yellow Fever Outbreak in the Northeastern Region of São Paulo State

2019 ◽  
Vol 2019 ◽  
pp. 1-11
Author(s):  
Márcio Junio Lima Siconelli ◽  
Danillo Lucas Alves Espósito ◽  
Nathália Cristina Moraes ◽  
Julia Maria Ribeiro ◽  
Lívia Perles ◽  
...  
Keyword(s):  
Public Health ◽  
Yellow Fever ◽  
Sao Paulo ◽  
Human Populations ◽  
Hemorrhagic Disease ◽  
São Paulo ◽  
Sylvatic Cycle ◽  
Northeastern Region ◽  
Paulo State ◽  
São Paulo State

Yellow fever (YF) is a zoonotic arthropod-borne disease that is caused by the yellow fever virus (YFV) and characterized by a sylvatic and urban cycle. Its most severe presentation is manifested as a hemorrhagic disease, and it has been responsible for thousands of deaths in the last decades. This study describes the public health approaches taken to control the 2016-2017 YF outbreak in nonhuman primates (NHPs) that took place in the northeastern region of São Paulo state, Brazil. NHPs recovered from the field were necropsied, and YF diagnoses were made at the Laboratory of Molecular Virology, Ribeirão Preto Medical School and the Center of Pathology, Adolfo Lutz Institute of São Paulo. NHP samples were inoculated into Vero cells for YFV isolation. RNA extraction was performed directly from NHP tissues and tested by RT-qPCR. YFV-positive samples were confirmed by sequencing. Based on the rapid RT-qPCR results, surveillance actions were implemented in the entire region. Confirmatory histopathology and immunohistochemistry for YFV were also performed. Among nine NHPs, gross hepatic involvement was observed in six animals, five of which were YFV-RT-qPCR-positive. One YFV was isolated from the serum of an infant NHP. YFV RNA sequences diverged from the virus responsible for the last epizootic that occurred in São Paulo state, but it was similar to the current Brazilian epizootic. Public health actions included dissemination of information on YF transmission, investigation of the probable location of NHP infection, characterization of the environment, and subsequent creation of the blueprint from which prevention and control measures were implemented. The YFV sylvatic cycle occurred in the periurban areas of the northeastern region of São Paulo state, but no human cases were reported during this period, showing that integrated actions between human, animal, and environmental health professionals were critical to restrain the virus to the sylvatic cycle.

scholarly journals Seropositivity rates for toxoplasmosis, rubella, syphilis, cytomegalovirus, hepatitis and HIV among pregnant women receiving care at a public health service, São Paulo state, Brazil

2010 ◽  
Vol 14 (6) ◽  
pp. 601-605
Author(s):  
Márcia Aparecida dos Santos Gonçalves ◽  
Cinara de Cássia Brandão de Matos ◽  
Lígia Cosentino Junqueira Franco Spegiorin ◽  
Denise Cristina Mós Vaz Oliani ◽  
Antonio Hélio Oliani ◽  
...  
Keyword(s):  
Public Health ◽  
Health Service ◽  
Pregnant Women ◽  
Public Health Service ◽  
Sao Paulo ◽  
São Paulo ◽  
Paulo State ◽  
São Paulo State ◽  
Cytomegalovirus Hepatitis

scholarly journals Access to medication in the Public Health System and equity: populational health surveys in São Paulo, Brazil

2016 ◽  
Vol 19 (1) ◽  
pp. 26-37 ◽  
Author(s):  
Camila Nascimento Monteiro ◽  
Reinaldo José Gianini ◽  
Marilisa Berti de Azevedo Barros ◽  
Chester Luiz Galvão Cesar ◽  
Moisés Goldbaum
Keyword(s):  
Public Health ◽  
Public Sector ◽  
Health System ◽  
Socioeconomic Position ◽  
Concentration Index ◽  
Public Health System ◽  
Sao Paulo ◽  
São Paulo ◽  
Cross Sectional ◽  
The Public

ABSTRACT: Introduction: Since 2003, the access to medication has been increasing in Brazil and particularly in São Paulo. The present study aimed to analyze the access to medication obtained in the public sector and the socioeconomic differences in this access in 2003 and 2008. Also, we explored the difference in access to medication from 2003 to 2008. Method: Data were obtained from two cross-sectional population-based household surveys from São Paulo, Brazil (ISA-Capital 2003 and ISA-Capital 2008). Concentration curve and concentration index were calculated to analyze the associations between socioeconomic factors and access to medication in the public sector. Additionally, the differences between 2003 and 2008 regarding socioeconomic characteristics and access to medication were studied. Results: Access to medication was 89.55% in 2003 and 92.99% in 2008, and the proportion of access to medication did not change in the period. Access in the public sector increased from 26.40% in 2003 to 48.55% in 2008 and there was a decrease in the concentration index between 2003 and 2008 in access to medication in the public sector. Conclusions: The findings indicate an expansion of Brazilian Unified Health System (Sistema Único de Saúde ) users, with the inclusion of people of higher socioeconomic position in the public sector. As the SUS gives more support to people of lower socioeconomic position in terms of medication provision, the SUS tends to equity. Nevertheless, universal coverage for medication and equity in access to medication in the public sector are still challenges for the Brazilian public health system.

scholarly journals Investigation Route of the Coronary Patient in the Public Health System in Curitiba, São Paulo and in Incor - IMPACT Study

2014 ◽  
Author(s):  
Juliano J. Cerci ◽  
Evelinda Trindade ◽  
Rodrigo Julio Cerci ◽  
Daniel Preto ◽  
Pedro A. Lemos ◽  
...  
Keyword(s):  
Public Health ◽  
Health System ◽  
Public Health System ◽  
Sao Paulo ◽  
São Paulo ◽  
Impact Study ◽  
The Public ◽  
Coronary Patient

scholarly journals Judicialização da saúde pública no Brasil: padrões e divergências decisórias na Justiça Civil Comum do Estado de São Paulo, Comarca de Campinas | Judicialization of public health in Brazil: standards and decisional disagreements of the Common Civil Court of Sao Paulo State, judicial district of Campinas

KPGT_dlutz_1 ◽  
2017 ◽  
Vol 31 (2) ◽  
pp. 386
Author(s):  
Keyla Ketlyn Passos Pimenta ◽  
Oswaldo Gonçalves Junior
Keyword(s):  
Public Health ◽  
Quantitative Methods ◽  
Sao Paulo ◽  
São Paulo ◽  
Judicial Process ◽  
Qualitative And Quantitative Methods ◽  
Civil Court ◽  
Paulo State ◽  
São Paulo State ◽  
The Common

Resumo: O presente estudo busca identificar e analisar padrões decisórios da Justiça Civil Comum do Estado de São Paulo, em primeira e segunda instância, quanto ao fenômeno da judicialização da saúde pública, com base em um conjunto de ações judicias oriundas da Comarca de Campinas e julgadas pelo tribunal no ano de 2012. Trata-se de estudo empírico, descritivo e retrospectivo, cujos dados foram coletados por meio de consulta aos processos judiciais. Utiliza de métodos qualitativos e quantitativos de análise. Os resultados revelam determinados padrões nas causas estudadas e a ocorrência de divergências entre os padrões decisórios de primeira e segunda instância. As decisões em primeira instância, mais diversas, indicam relações com outros elementos processuais, como a patologia declarada, inclinação pessoal do magistrado, contato mais próximo com gestores públicos locais, entre outros. Palavras-chave: Divergências decisórias. Judicialização da saúde pública. Poder judiciário. Padrões decisórios. Abstract: This study aims to identify and to analyze decisional standards of the Common Civil Court of São Paulo State, in first and second instance, regarding to the phenomenon of public health judicialization, based on series of lawsuits from the Judicial District of Campinas and judged by the court in the year of 2012. This is an empirical, descriptive and retrospective study, which data were collected through the consultation of lawsuits. The study uses qualitative and quantitative methods of analysis. The results reveal certain standards in the lawsuits and the occurrence of divergences between first and second instance decisional standards. The decisions at first instance, diversified, indicate relations with other elements of the judicial process, such as the declared pathology, personal inclination of the judge, closer contact with local public managers, among others. Keywords: Decisional standards. Decisional divergences. Judicialization of public health. Judiciary.

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