scholarly journals Antisense to transforming growth factor-β1 messenger RNA reduces vein graft intimal hyperplasia and monocyte chemotactic protein 1

2005 ◽  
Vol 41 (3) ◽  
pp. 498-508 ◽  
Author(s):  
Randal A. Wolff ◽  
Masaaki Ryomoto ◽  
V. Emily Stark ◽  
Rita Malinowski ◽  
Jeffrey J. Tomas ◽  
...  
Keyword(s):  
Growth Factor ◽  
Intimal Hyperplasia ◽  
Vein Graft ◽  
Messenger Rna ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Monocyte Chemotactic Protein ◽  
Chemotactic Protein

Immune imbalance of regulatory T/type 2 helper cells in the pathogenesis of allergic rhinitis in children

2015 ◽  
Vol 130 (1) ◽  
pp. 89-94 ◽  
Author(s):  
R Sun ◽  
X-Y Tang ◽  
Y Yang
Keyword(s):  
Allergic Rhinitis ◽  
Growth Factor ◽  
Messenger Rna ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Clinical Severity ◽  
Helper Cell ◽  
Helper Cells ◽  
Immune Imbalance

AbstractObjectives:To determine the role of regulatory T/type 2 helper cell-mediated immune imbalance in the pathogenesis of allergic rhinitis and examine the association between clinical severity and regulatory T/type 2 helper cell-mediated immune imbalance.Methods:Levels of interleukins 4 and 5 and transforming growth factor β1, and expression of FOXP3 and GATA3 (which are functionally related to regulatory T and type 2 helper cells, respectively), were evaluated in 46 allergic rhinitis patients and 42 healthy subjects.Results:Compared to controls, allergic rhinitis patients showed significantly higher interleukin 4 and 5 levels, but lower transforming growth factor β1 levels. Furthermore, FOXP3 messenger RNA expression was lower in allergic rhinitis patients, while GATA3 messenger RNA and protein expression was significantly higher. Regulatory T/type 2 helper cell ratio was inversely correlated with clinical symptom scores.Conclusion:Regulatory T/type 2 helper cell immune imbalance may contribute to allergic rhinitis development. These findings provide a new insight into disease pathogenesis and potential therapeutic approaches.

Estrogen Replacement Inhibits Intimal Hyperplasia and the Accumulation and Effects of Transforming Growth Factor β1

1998 ◽  
Vol 80 (2) ◽  
pp. 380-385 ◽  
Author(s):  
Craig H. Selzman ◽  
Jaime S. Gaynor ◽  
A.Simon Turner ◽  
Thomas A. Whitehill ◽  
Lawrence D. Horwitz ◽  
...  
Keyword(s):  
Growth Factor ◽  
Intimal Hyperplasia ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Estrogen Replacement

Transforming Growth Factor-β1 Suppresses Thyrotropin-Induced Na+/I- Symporter Messenger RNA and Protein Levels in FRTL-5 Rat Thyroid Cells

Thyroid ◽  
1997 ◽  
Vol 7 (5) ◽  
pp. 789-794 ◽  
Author(s):  
AKIO KAWAGUCHI ◽  
MASATO IKEDA ◽  
TOYOSHI ENDO ◽  
TAKAHIKO KOGAI ◽  
ASAKO MIYAZAKI ◽  
...  
Keyword(s):  
Growth Factor ◽  
Messenger Rna ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Thyroid Cells ◽  
Protein Levels ◽  
Rat Thyroid

Transforming growth factor β1 and fibronectin messenger RNA in rat brain: Responses to injury and cell-type localization

Neuroscience ◽  
1993 ◽  
Vol 54 (4) ◽  
pp. 893-907 ◽  
Author(s):  
G.M. Pasinetti ◽  
N.R. Nichols ◽  
G. Tocco ◽  
T. Morgan ◽  
N. Laping ◽  
...  
Keyword(s):  
Growth Factor ◽  
Rat Brain ◽  
Messenger Rna ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Cell Type ◽  
Brain Responses

Transforming Growth Factor β1 and Coronary Intimal Hyperplasia in Pediatric Patients With Congenital Heart Disease

2013 ◽  
Vol 29 (7) ◽  
pp. 849-857 ◽  
Author(s):  
Roberto A. Guerri-Guttenberg ◽  
Rocío Castilla ◽  
Gabriela C. Francos ◽  
Angélica Müller ◽  
Giuseppe Ambrosio ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Growth Factor ◽  
Intimal Hyperplasia ◽  
Congenital Heart ◽  
Pediatric Patients ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1
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