Good dispersion of poly(δ-gluconolactone)-grafted graphene in poly(vinyl alcohol) for significantly enhanced mechanical strength

2020 ◽  
Vol 254 ◽  
pp. 123465 ◽  
Author(s):  
Emad S. Goda ◽  
Bal Sydulu Singu ◽  
Sang Eun Hong ◽  
Kuk Ro Yoon
2016 ◽  
Vol 36 (8) ◽  
pp. 771-784 ◽  
Author(s):  
Tejinder Kaur ◽  
Arunachalam Thirugnanam ◽  
Krishna Pramanik

Abstract Poly(vinyl alcohol) reinforced with nanohydroxyapatite (PVA-nHA) composite scaffolds were developed by varying the nHA (1%, 2%, 3%, 4%, and 5%, w/v) composition in the PVA matrix by solvent casting technique. The developed composite scaffolds were characterized using scanning electron microscopy (SEM), X-ray powder diffraction (XRD), attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy, and contact angle measurement. The stability of the composite scaffolds in physiological environment was evaluated by swelling and degradation studies. Further, these composite scaffolds were tested for in vitro bioactivity, hemolysis, biocompatibility, and mechanical strength. SEM micrographs showed a homogenous distribution of nHA (3%, w/v) in the PVA matrix. XRD and ATR-FTIR analysis confirmed no phase contamination and the existence of the chemical bond between PVA-nHA at approximately 2474 cm-1. PVA-nHA composite scaffolds with 3% (w/v) concentration of nHA showed nominal swelling and degradation behavior with good mechanical strength. The mechanical strength and degradation properties of the scaffold above 3% (w/v) of nHA was found to deteriorate, which is due to the agglomeration of nHA. The in vitro bioactivity and hemolysis studies showed improved apatite formation and hemocompatibility of the developed scaffolds. In vitro cell adhesion, proliferation, alkaline phosphatase activity, and Alizarin red S staining confirmed the biocompatibility of the composite scaffolds.


2008 ◽  
Vol 272 (1) ◽  
pp. 150-155 ◽  
Author(s):  
Sung-Yeng Yang ◽  
Chia-I Liu ◽  
Jing-Yi Wu ◽  
Ju-Chien Kuo ◽  
Chi-Yuan Huang

2009 ◽  
Vol 66 (9) ◽  
pp. 349-354 ◽  
Author(s):  
Hidenobu SHIMIZU ◽  
Risei WADA ◽  
Masaru OKABE

2016 ◽  
Vol 32 (4) ◽  
pp. 411-428 ◽  
Author(s):  
Nor Hasrul Akhmal Ngadiman ◽  
Noordin Mohd Yusof ◽  
Ani Idris ◽  
Denni Kurniawan ◽  
Ehsan Fallahiarezoudar

The use of electrospinning has gained substantial interest in the development of tissue engineering scaffolds due to its ability to produce nanoscale fibers which can mimic the geometry of extracellular tissues. Besides geometry, mechanical property is one of the main elements to be considered when developing tissue engineering scaffolds. In this study, the electrospinning process parameter settings were varied in order to find the optimum setting which can produce electrospun nanofibrous mats with good mechanical properties. Maghemite (γ-Fe2O3) was mixed with poly(vinyl alcohol) and then electrospun to form nanofibers. The five input variable factors involved were nanoparticles content, voltage, flow rate, spinning distance, and rotating speed, while the response variable considered was Young’s modulus. The performance of electrospinning process was systematically screened and optimized using response surface methodology. This work truly demonstrated the sequential nature of designed experimentation. Additionally, the application of various designs of experiment techniques and concepts was also demonstrated. Results revealed that electrospun nanofibrous mats with maximum Young’s modulus (273.51 MPa) was obtained at optimum input settings: 9 v/v% nanoparticle content, 35 kV voltage, 2 mL/h volume flow rate, 8 cm spinning distance, and 3539 r/min of rotating speed. The model was verified successfully by performing confirmation experiments. The nanofibers characterization demonstrated that the nanoparticles were well dispersed inside the nanofibers, and it also showed that the presence of defects on the nanofibers can decrease their mechanical strength. The biocompatibility performance was also evaluated and it was proven that the presence of γ-Fe2O3 enhanced the cell viability and cell growth rate. The developed poly(vinyl alcohol)/γ-Fe2O3 electrospun nanofiber mat has a good potential for tissue engineering scaffolds.


RSC Advances ◽  
2014 ◽  
Vol 4 (99) ◽  
pp. 56373-56384 ◽  
Author(s):  
Yuan-Hsiang Yu ◽  
Chih-Chieh Chan ◽  
Yu-Chia Lai ◽  
Yan-Yu Lin ◽  
Ying-Chieh Huang ◽  
...  

Biocompatible poly(vinyl alcohol) nanocomposite electrospun nanofibres embedded with glycine-modified graphene oxide and nanogold-deposited graphene oxide with substantially enhanced conductivity, mechanical strength, and thermal stability.


2001 ◽  
Vol 21 (8) ◽  
pp. 1087-1092 ◽  
Author(s):  
Samir Baklouti ◽  
Jamel Bouaziz ◽  
Thierry Chartier ◽  
Jean-François Baumard

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