Tribological and rheological evaluation of a graphene nanosheets-based lubricant for metal-on-metal and wet clutch interfaces

2021 ◽  
pp. 131441
Author(s):  
Julio Cao-Romero-Gallegos ◽  
Leonardo Farfan-Cabrera ◽  
José Pérez-González ◽  
Benjamín Marín-Santibáñez
Keyword(s):  
Graphene Nanosheets ◽  
Metal On Metal ◽  
Wet Clutch

Eosinophilic Metallosis: A Newly Described Entity in Failed Metal-on-Metal Arthroplasty

2016 ◽  
Vol 26 (4) ◽  
pp. 341-346
Author(s):  
Brandon Levy ◽  
A. Hanflik ◽  
E. Bryk ◽  
V. J. Vigorita
Keyword(s):  
Metal On Metal

A Comprehensive Insight Towards Pharmaceutical Aspects of Graphene Nanosheets

2020 ◽  
Vol 21 (11) ◽  
pp. 1016-1027 ◽  
Author(s):  
Fatemeh Emadi ◽  
Arash Emadi ◽  
Ahmad Gholami
Keyword(s):  
Targeted Delivery ◽  
Graphene Nanosheets ◽  
High Surface ◽  
High Surface Area ◽  
Charge Carriers ◽  
Pharmaceutical Sciences ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Mobility Of Charge Carriers ◽  
Graphene Derivatives ◽  
Pharmacokinetic Properties

Graphene Derivatives (GDs) have captured the interest and imagination of pharmaceutical scientists. This review exclusively provides pharmacokinetics and pharmacodynamics information with a particular focus on biopharmaceuticals. GDs can be used as multipurpose pharmaceutical delivery systems due to their ultra-high surface area, flexibility, and fast mobility of charge carriers. Improved effects, targeted delivery to tissues, controlled release profiles, visualization of biodistribution and clearance, and overcoming drug resistance are examples of the benefits of GDs. This review focuses on the application of GDs for the delivery of biopharmaceuticals. Also, the pharmacokinetic properties and the advantage of using GDs in pharmaceutics will be reviewed to achieve a comprehensive understanding about the GDs in pharmaceutical sciences.

Noncovalent Functionalization of Graphene Nanosheets with Cluster-Cored Star Polymers and Their Reinforced Polymer Coating

2015 ◽  
Vol 4 (9) ◽  
pp. 974-978 ◽  
Author(s):  
Shan Wang ◽  
Haolong Li ◽  
Dan Li ◽  
Tianyang Xu ◽  
Shilin Zhang ◽  
...  
Keyword(s):  
Polymer Coating ◽  
Graphene Nanosheets ◽  
Star Polymers ◽  
Reinforced Polymer ◽  
Noncovalent Functionalization

Chemically Converted Graphene Nanosheets for the Construction of Ion-Exclusion Nanochannel Membranes

Nano Letters ◽  
2021 ◽  
Author(s):  
Kecheng Guan ◽  
Yuandong Jia ◽  
Yuqing Lin ◽  
Shengyao Wang ◽  
Hideto Matsuyama
Keyword(s):  
Graphene Nanosheets ◽  
Ion Exclusion ◽  
Chemically Converted Graphene

scholarly journals Whole blood chromium concentration is very rarely elevated independently of whole blood cobalt

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Olli Lainiala ◽  
Mari Karsikas ◽  
Aleksi Reito ◽  
Antti Eskelinen
Keyword(s):  
Whole Blood ◽  
Cost Savings ◽  
Chromium Concentration ◽  
Continuous Variables ◽  
Metal Debris ◽  
Screening Guidelines ◽  
Metal On Metal ◽  
Hip Replacements

AbstractDue to the risk of adverse reactions to metal debris resulting from increased wear of the arthroplasty more than one million metal-on-metal (MoM) hip replacements worldwide are in active follow-up. Follow-up usually includes measurement of both whole blood cobalt (Co) and chromium (Cr) concentrations. Our experience is that Cr is seldom independently elevated. We wanted to ascertain whether blood Cr measurements could be omitted from follow-up protocols without lowering the quality of follow-up. We identified 8438 whole blood Co and Cr measurements performed without or prior to revision surgery. When the cut-off levels 5 µg/L and 7 µg/L were used, Cr was independently elevated in only 0.5% (95% confidence interval, CI, 0.3 to 0.6) and 0.2% (CI 0.1 to 0.3) of the measurements. The models with continuous variables showed that the higher the blood metal concentrations are the lower the percentage of measurements with Cr higher than Co. Our results suggest that whole blood Cr is very rarely independently elevated and therefore the authorities should consider omitting Cr measurements from their screening guidelines of MoM hip replacements. We believe this change in practice would simplify follow-up and lead to cost savings without decreasing the quality of follow-up.

scholarly journals Uncemented versus cemented arthroplasty after metal-on-metal total hip replacement in patients with femoral neck fractures: a retrospective study

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110122
Author(s):  
Wenlu Liu ◽  
Huanyi Lin ◽  
Xianshang Zeng ◽  
Meiji Chen ◽  
Weiwei Tang ◽  
...  
Keyword(s):  
Femoral Neck ◽  
Clinical Outcomes ◽  
Total Hip Replacement ◽  
Hip Replacement ◽  
Femoral Neck Fractures ◽  
Harris Hip Score ◽  
Complication Rates ◽  
Total Hip ◽  
Metal On Metal

Objective To compare the clinical outcomes of primary metal-on-metal total hip replacement (MoM-TR) converted to uncemented total hip replacement (UTR) or cemented total hip replacement (CTR) in patients with femoral neck fractures (AO/OTA: 31B/C). Methods Patient data of 234 UTR or CTR revisions after primary MoM-TR failure from March 2007 to January 2018 were retrospectively identified. Clinical outcomes, including the Harris hip score (HHS) and key orthopaedic complications, were collected at 3, 6, and 12 months following conversion and every 12 months thereafter. Results The mean follow-up was 84.12 (67–100) months for UTR and 84.23 (66–101) months for CTR. At the last follow-up, the HHS was better in the CTR- than UTR-treated patients. Noteworthy dissimilarities were correspondingly detected in the key orthopaedic complication rates (16.1% for CTR vs. 47.4% for UTR). Statistically significant differences in specific orthopaedic complications were also detected in the re-revision rate (10.3% for UTR vs. 2.5% for CTR), prosthesis loosening rate (16.3% for UTR vs. 5.9% for CTR), and periprosthetic fracture rate (12.0% for UTR vs. 4.2% for CTR). Conclusion In the setting of revision of failed primary MoM-TR, CTR may demonstrate advantages over UTR in improving functional outcomes and reducing key orthopaedic complications.

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