Effect of HRT on hormone responses to resistance exercise in post-menopausal women

Maturitas ◽  
2004 ◽  
Vol 48 (4) ◽  
pp. 360-371 ◽  
Author(s):  
Jennifer L Copeland ◽  
Mark S Tremblay
2020 ◽  
Author(s):  
Kyu-Min Park ◽  
Seung-Taek Lim ◽  
Kun-Young Sung ◽  
Sunghwun Kang

Abstract Background and objectives: The purpose of study was to examine the effects of regular resistance exercise for 12 weeks on lipolysis pathway in pre- and post- menopausal women with obesity. Methods: Twenty-three pre- and post- menopausal women with body fat percentages of 30% or more divided into pre- menopausal group (n=9) and post- menopausal group (n=14). All subjects participated in resistance exercise training for 12 weeks. Anthropometric and physical fitness tests were performed on all participants. Protein analyses were performed with subcutaneous fatty tissue extracted, and the samples were analyzed of relevant protein levels changes by using Western blotting. All serum samples were submitted for enzyme-linked immunosorbent assay measurements of adipocyte factors. Results: After 12 weeks between pre- menopausal and post- menopausal groups adipose triglyceride lipase (ATGL), monoacylglycerol lipase (MGL) and perilipin (PLIN) protein levels were significantly lower in the post- menopausal group than in the pre- menopausal group. Hormone-sensitive lipase (HSL) protein levels were significantly higher in the post- menopausal group than in the pre- menopausal group. In addition, leptin concentration was significantly decreased after resistance exercise in the post- menopausal group. Adiponectin concentration was significantly increased after resistance exercise in the both groups. Conclusions: This study indicates that regular resistance exercise to change of leptin and adiponectin might be release of reduction of % fat, and driving overall greater change ATGL, HSL, MGL and PLIN levels in subcutaneous fatty tissue in the obese post- menopausal group more than obese pre- menopausal group.


2020 ◽  
Author(s):  
Kyu-Min Park ◽  
Seung-Taek Lim ◽  
Kun-Young Sung ◽  
Sunghwun Kang

Abstract Background The purpose of study was to examine the effects of regulatory resistance exercise for 12 weeks on lipolysis pathway in pre- and post- menopausal women with obesity. Methods Twenty-three pre- and post- menopausal women with body fat percentages of 30% or more divided into pre- menopausal group (n = 9) and post- menopausal group (n = 14). All subjects participated in resistance exercise training for 12 weeks. All participant’s anthropometric measurements and physical fitness tests were performed. Protein analyses were performed with subcutaneous fatty tissue extracted, and the samples were analyzed of relevant protein expression changes by using Western blotting. All serum samples were submitted for enzyme-linked immunosorbent assay measurements of adipocyte factors. Results After 12 weeks between pre- menopausal and post- menopausal groups ATGL, MGL and PLIN protein expression were significantly lower in the post- menopausal group than in the pre- menopausal group. HSL protein expression were significantly higher in the post- menopausal group than in the pre- menopausal group. In addition, leptin concentration was significantly decreased, and adiponectin concentration was significantly increased after resistance exercise in the post- menopausal group more than pre- menopausal group. Conclusions In this study indicates that regular resistance exercise to change of leptin and adiponectin might be release of overall decreased ATGL, HSL, MGL and PLIN expression in subcutaneous fatty tissue, and driving reduction of % fat in the obese post- menopausal group more than obese pre- menopausal group.


2005 ◽  
Vol 37 (Supplement) ◽  
pp. S219
Author(s):  
Gary Pierce ◽  
Mark C. Mering ◽  
Kathy S. Howe ◽  
Wilmer W. Nichols ◽  
Randy W. Braith

2020 ◽  
Author(s):  
Kyu-Min Park ◽  
Seung-Taek Lim ◽  
Kun-Young Sung ◽  
Sunghwun Kang

Abstract Background and objectives: The purpose of study was to examine the effects of regulatory resistance exercise for 12 weeks on lipolysis pathway in pre- and post- menopausal women with obesity. Methods: Twenty-three pre- and post- menopausal women with body fat percentages of 30% or more divided into pre- menopausal group (n=9) and post- menopausal group (n=14). All subjects participated in resistance exercise training for 12 weeks. All participant’s anthropometric measurements and physical fitness tests were performed. Protein analyses were performed with subcutaneous fatty tissue extracted, and the samples were analyzed of relevant protein expression changes by using Western blotting. All serum samples were submitted for enzyme-linked immunosorbent assay measurements of adipocyte factors. Results: After 12 weeks between pre- menopausal and post- menopausal groups ATGL, MGL and PLIN protein expression were significantly lower in the post- menopausal group than in the pre- menopausal group. HSL protein expression were significantly higher in the post- menopausal group than in the pre- menopausal group. In addition, leptin concentration was significantly decreased, and adiponectin concentration was significantly increased after resistance exercise in the post- menopausal group more than pre- menopausal group. Conclusions: In this study indicates that regular resistance exercise to change of leptin and adiponectin might be release of overall decreased ATGL, HSL, MGL and PLIN expression in subcutaneous fatty tissue, and driving reduction of % fat in the obese post- menopausal group more than obese pre- menopausal group.


2005 ◽  
Vol 37 (Supplement) ◽  
pp. S219
Author(s):  
Gary Pierce ◽  
Mark C. Mering ◽  
Kathy S. Howe ◽  
Wilmer W. Nichols ◽  
Randy W. Braith

Author(s):  
Zeinab Momeni ◽  
Jessica E. Logan ◽  
Ronald J. Sigal ◽  
Jane E. Yardley

Due to improvements in diabetes care, people with type 1 diabetes (T1D) are living longer. Studies show that post-menopausal T1D women have a substantially elevated cardiovascular risk compared to those without T1D. As T1D may also accelerate age-related bone and muscle loss, the risk of frailty may be considerable for T1D women. Exercise and physical activity may be optimal preventative therapies to maintain health and prevent complications in this population: They are associated with improvements in, or maintenance of, cardiovascular health, bone mineral density, and muscle mass in older adults. Resistance exercise, in particular, may provide important protection against age-related frailty, due to its specific effects on bone and muscle. Fear of hypoglycemia can be a barrier to exercise in those with T1D, and resistance exercise may cause less hypoglycemia than aerobic exercise. There are currently no exercise studies involving older, post-menopausal women with T1D. As such, it is unknown whether current guidelines for insulin adjustment/carbohydrate intake for activity are appropriate for this population. This review focuses on existing knowledge about exercise in older adults and considers potential future directions around resistance exercise as a therapeutic intervention for post-menopausal T1D women.


Sign in / Sign up

Export Citation Format

Share Document