Easy size control of polymer nanoparticles obtained by emulsification–evaporation technique in a microfluidic reactor

2021 ◽  
Vol 31 (6) ◽  
pp. 899-901
Author(s):  
Maria A. Merkulova ◽  
Nadezhda S. Osipova ◽  
Olga O. Maksimenko ◽  
Maria G. Gordienko ◽  
Svetlana E. Gelperina
Keyword(s):  
Size Control ◽  
Polymer Nanoparticles ◽  
Microfluidic Reactor ◽  
Evaporation Technique

Size Control of Spherical and Anisotropic Fluorescent Polymer Nanoparticles via Precise Rigid Molecules

2015 ◽  
Vol 48 (12) ◽  
pp. 3900-3906 ◽  
Author(s):  
Friederike Schütze ◽  
Marina Krumova ◽  
Stefan Mecking
Keyword(s):  
Size Control ◽  
Polymer Nanoparticles ◽  
Fluorescent Polymer

Active Polymer Nanoparticles: Delivery of Antibiotics

2007 ◽  
Vol 1019 ◽  
Author(s):  
Monica Rabinovich ◽  
Shankari N. Somayaji ◽  
Rajeev Raghavan Pillai ◽  
Michael C. Hudson ◽  
J. Kent Ellington ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Drug Loading ◽  
Plga Nanoparticles ◽  
Polymer Nanoparticles ◽  
Copolymer Composition ◽  
Zns Nanoparticles ◽  
Primary Mouse ◽  
Evaporation Technique ◽  
Uv Visible ◽  
Scanning Electron

AbstractAntibiotic-encapsulated PLA and PLGA nanoparticles were prepared by the single emulsion-solvent evaporation technique. Different PLA and PLGA systems were prepared, varying the copolymer composition and the amount of the surfactant polyvinyl alcohol. Characterization and drug loading studies were performed by UV-Visible spectrophotometry, dynamic light scattering, and scanning electron microscopy (SEM).Simultaneously, in order to model the diffusion of the nanoparticles within the osteoblast, QDs such as functionalized InGaP/ZnS and polymer encapsulated InGaP/ZnS nanoparticles were added to confluent cultures of primary mouse osteoblasts. Following PreFer fixation, cultures were examined via confocal microscopy. QDs were clearly visible within osteoblasts.

Adhesion to Cells of Enzyme Conjugated Phospholipid Polymer Nanoparticles

2007 ◽  
Vol 342-343 ◽  
pp. 785-788
Author(s):  
Tomomi Ito ◽  
Tomohiro Konno ◽  
Madoka Takai ◽  
Kazuhiko Ishihara
Keyword(s):  
Enzyme Activity ◽  
Lactic Acid ◽  
Glutamic Acid ◽  
Polymer Nanoparticles ◽  
Butyl Methacrylate ◽  
Ph Change ◽  
Surface Modifier ◽  
Phospholipid Polymer ◽  
Evaporation Technique ◽  
Mixture System

We investigated the bioconjugation of proteins on polymer nanoparticles covered with bio-inert phosphorylcholine groups. Poly[2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate-co-p-nitrophenyloxycarbonyl polyethyleneglycol methacrylate] was used as an emulsifier and a surface modifier to prepare the poly (L-lactic acid) nanoparticles by a solvent evaporation technique. The diameter and surface potential of the nanoparticles were approximately 260 nm and –5 mV, respectively. We considered that the polymer chain that transformed the conformation by change in pH may be used as a method of controlling the bioreaction. The enzyme activity in a different pH under the coexistence of poly (glutamic acid) (PGA) and the enzyme was measured. Therefore, the enzyme activity increased in pH 6 in PGA/enzyme mixture system compared with that in pH 7 while the activity was constant in the enzyme single conjugation regardless of the pH change.

scholarly journals Size Control of Polymer Nanoparticles Using 3D Network Structure as a Reaction Field

2021 ◽  
Vol 58 (9) ◽  
pp. 481-485
Author(s):  
Shinya Ouchi ◽  
Naoki Yamada ◽  
Tetsuya Yamamoto
Keyword(s):  
Network Structure ◽  
Size Control ◽  
Polymer Nanoparticles ◽  
Reaction Field ◽  
3D Network

Interfacial studies in Nb3Sn superconductors

1991 ◽  
Vol 49 ◽  
pp. 590-591
Author(s):  
Ernest L. Hall ◽  
Lee E. Rumaner ◽  
Mark G. Benz
Keyword(s):  
Grain Size ◽  
Grain Boundaries ◽  
Flux Pinning ◽  
Size Control ◽  
High Magnetic Fields ◽  
Type Ii ◽  
Reaction Interface ◽  
Liquid Diffusion ◽  
Type Ii Superconductor ◽  
Grain Size Control

The intermetallic compound Nb3Sn is a type-II superconductor of interest because it has high values of critical current density Jc in high magnetic fields. One method of forming this compound involves diffusion of Sn into Nb foil containing small amounts of Zr and O. In order to maintain high values of Jc, it is important to keep the grain size in the Nb3Sn as small as possible, since the grain boundaries act as flux-pinning sites. It has been known for many years that Zr and O were essential to grain size control in this process. In previous work, we have shown that (a) the Sn is transported to the Nb3Sn/Nb interface by liquid diffusion along grain boundaries; (b) the Zr and O form small ZrO2 particles in the Nb3Sn grains; and (c) many very small Nb3Sn grains nucleate from a single Nb grain at the reaction interface. In this paper we report the results of detailed studies of the Nb3Sn/Nb3Sn, Nb3Sn/Nb, and Nb3Sn/ZrO2 interfaces.

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