A “turn-on” electrochemical aptasensor for ultrasensitive detection of Cd2+ using duplexed aptamer switch on electrochemically reduced graphene oxide electrode

2020 ◽  
Vol 159 ◽  
pp. 105372
Author(s):  
Chang-Seuk Lee ◽  
Su Hwan Yu ◽  
Tae Hyun Kim
2015 ◽  
Vol 3 (13) ◽  
pp. 6921-6928 ◽  
Author(s):  
Xiaowen Yu ◽  
Miao Zhang ◽  
Wenjing Yuan ◽  
Gaoquan Shi

Ni–Fe layered double hydroxide nanoplates loaded on a three-dimensional electrochemically reduced graphene oxide electrode for efficient water oxidation, exhibiting higher activity, kinetics, and stability than those of the IrO2catalyst.


Nanomaterials ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 817 ◽  
Author(s):  
Su Hwan Yu ◽  
Chang-Seuk Lee ◽  
Tae Hyun Kim

This paper describes a simple strategy for the ultratrace level detection of Pb2+ ion based on G-quadruplex DNA and an electrochemically reduced graphene oxide (ERGO) electrode. First, ERGO was formed on a glassy carbon electrode (GCE) by the reduction of graphene oxide (GO) using cyclic voltammetry. Subsequently, a methylene blue (MB)-tagged, guanine-rich DNA aptamer (Apt) was attached to the surface of ERGO via π-π interaction, leading to the Apt-modified ERGO electrode. The presence of Pb2+ could generate the folding of Apt to a G-quadruplex structure. The formation of G-quadruplex resulted in detaching the Apt from the ERGO/GCE, leading to a change in redox current of the MB tag. Electrochemical measurements showed the proposed sensor had an exceptional sensitivity for Pb2+ with a linear range from 10−15 to 10−9 M and a detection limit of 0.51 fM. The sensor also exhibited high selectivity for Pb2+, as well as many other advantages, such as stability, reproducibility, regeneration, as well as simple fabrication and operation processes.


Sign in / Sign up

Export Citation Format

Share Document