Mesoporous silica nanoparticles capped with graphene quantum dots as multifunctional drug carriers for photo-thermal and redox-responsive release

2019 ◽  
Vol 278 ◽  
pp. 130-137 ◽  
Author(s):  
Yan Gao ◽  
Shuangling Zhong ◽  
Lifeng Xu ◽  
Shihao He ◽  
Yueming Dou ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Graphene Quantum Dots ◽  
Drug Carriers ◽  
Redox Responsive

Mesoporous Silica Nanoparticles Capped with Graphene Quantum Dots for Potential Chemo–Photothermal Synergistic Cancer Therapy

Langmuir ◽  
2016 ◽  
Vol 33 (2) ◽  
pp. 591-599 ◽  
Author(s):  
Xianxian Yao ◽  
Zhengfang Tian ◽  
Jiaxing Liu ◽  
Yufang Zhu ◽  
Nobutaka Hanagata
Keyword(s):  
Quantum Dots ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Graphene Quantum Dots

scholarly journals In vivo targeting of breast cancer with a vasculature-specific GQDs/hMSN nanoplatform

RSC Advances ◽  
2019 ◽  
Vol 9 (20) ◽  
pp. 11576-11584 ◽  
Author(s):  
Jingjing Dong ◽  
Xinyue Yao ◽  
Shian Sun ◽  
Yuanyuan Zhong ◽  
Chuntong Qian ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quantum Dots ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Previous Experiment ◽  
Mesoporous Silica Nanoparticles ◽  
Graphene Quantum Dots ◽  
Medical Applications ◽  
Hollow Mesoporous Silica

According to our previous experiment, graphene quantum dots capped in hollow mesoporous silica nanoparticles, denoted as GQDs@hMSN, and its conjugates exhibited great potential for medical applications due to their commendable biocompatibility.

Exploiting mesoporous silica nanoparticles as versatile drug carriers for several routes of administration

2021 ◽  
Vol 312 ◽  
pp. 110774
Author(s):  
Rafael Miguel Sábio ◽  
Andréia Bagliotti Meneguin ◽  
Aline Martins dos Santos ◽  
Andreia Sofia Monteiro ◽  
Marlus Chorilli
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carriers ◽  
Routes Of Administration

scholarly journals Mesoporous Silica Nanoparticles for Targeting Subcellular Organelles

2020 ◽  
Vol 21 (24) ◽  
pp. 9696
Author(s):  
Miguel Gisbert-Garzarán ◽  
Daniel Lozano ◽  
María Vallet-Regí
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
State Of The Art ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Distribution ◽  
Chemical Properties ◽  
Drug Carriers ◽  
Subcellular Organelles ◽  
Physico Chemical ◽  
Tumoral Cells

Current chemotherapy treatments lack great selectivity towards tumoral cells, which leads to nonspecific drug distribution and subsequent side effects. In this regard, the use of nanoparticles able to encapsulate and release therapeutic agents has attracted growing attention. In this sense, mesoporous silica nanoparticles (MSNs) have been widely employed as drug carriers owing to their exquisite physico-chemical properties. Because MSNs present a surface full of silanol groups, they can be easily functionalized to endow the nanoparticles with many different functionalities, including the introduction of moieties with affinity for the cell membrane or relevant compartments within the cell, thus increasing the efficacy of the treatments. This review manuscript will provide the state-of-the-art on MSNs functionalized for targeting subcellular compartments, focusing on the cytoplasm, the mitochondria, and the nucleus.

Tunable multi-responsive nano-gated mesoporous silica nanoparticles as drug carriers

2021 ◽  
pp. 112119
Author(s):  
Riyasudheen Nechikkattu ◽  
Jungwon Kong ◽  
Young-Shin Lee ◽  
Hyun-Jung Moon ◽  
Jae-Ho Bae ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carriers

Redox-Responsive Nanocarrier Based on Heparin End-Capped Mesoporous Silica Nanoparticles for Targeted Tumor Therapy in Vitro and in Vivo

Langmuir ◽  
2014 ◽  
Vol 30 (26) ◽  
pp. 7867-7877 ◽  
Author(s):  
Liangliang Dai ◽  
Jinghua Li ◽  
Beilu Zhang ◽  
Junjie Liu ◽  
Zhong Luo ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Tumor Therapy ◽  
Redox Responsive
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