DNA Methylation-Based Point-of-Care Cancer Detection: Challenges and Possibilities

2019 ◽  
Vol 25 (11) ◽  
pp. 955-966 ◽  
Author(s):  
Abu Ali Ibn Sina ◽  
Laura G. Carrascosa ◽  
Matt Trau
Keyword(s):  
Dna Methylation ◽  
Cancer Detection ◽  
Point Of Care

scholarly journals Standards for Plasma and Serum Proteomics in Early Cancer Detection: A Needs Assessment Report from the National Institute of Standards and Technology-National Cancer Institute Standards, Methods, Assays, Reagents and Technologies Workshop, August 18–19, 2005

2006 ◽  
Vol 52 (9) ◽  
pp. 1669-1674 ◽  
Author(s):  
Peter E Barker ◽  
Paul D Wagner ◽  
Stephen E Stein ◽  
David M Bunk ◽  
Sudhir Srivastava ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Needs Assessment ◽  
Reference Materials ◽  
Cancer Detection ◽  
National Cancer Institute ◽  
Early Cancer ◽  
Early Cancer Detection ◽  
Assessment Report ◽  
Serum Proteomics

Abstract NIST and the National Cancer Institute cosponsored a workshop on August 18–19, 2005, to examine needs for reference materials for early cancer detection. This meeting focused on standards, methods, assays, reagents, and technologies. Needs for plasma and serum proteomics, DNA methylation, and specimen reference collections were discussed, and recommendations from participants were solicited. This report summarizes the discussion and recommendations for proteomics reference materials.

scholarly journals Cervical cancer detection by DNA methylation analysis in urine

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Barbara C. Snoek ◽  
Annina P. van Splunter ◽  
Maaike C. G. Bleeker ◽  
Maartje C. van Ruiten ◽  
Daniëlle A. M. Heideman ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Dna Methylation ◽  
Cancer Detection ◽  
Methylation Analysis ◽  
Dna Methylation Analysis

DNA methylation markers for endometrial cancer detection in minimally invasive samples: a systematic review

Epigenomics ◽  
2020 ◽  
Vol 12 (18) ◽  
pp. 1661-1672 ◽  
Author(s):  
Rianne van den Helder ◽  
Birgit MM Wever ◽  
Jip A van Trommel ◽  
Johannes CF Ket ◽  
Maaike CG Bleeker ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Endometrial Cancer ◽  
Minimally Invasive ◽  
Cancer Detection ◽  
Area Under The Curve ◽  
Diagnostic Procedures ◽  
Screening Programs ◽  
High Risk Women ◽  
Promising Tool ◽  
Meta Analyses

Aim: DNA methylation testing for endometrial cancer detection in minimally invasive specimens is a promising tool to improve screening and diagnostic procedures. Available literature was systematically reviewed to assess the potential of this approach and define methylation markers deserving further development. Methods: A systematic search up to March 31 2020 was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Results: 15 methylation markers with an area under the curve value of ≥ 0.80 for endometrial cancer detection in cytological specimens were selected from nine studies. Conclusion: Detection of methylation markers in cytological samples indicate the feasibility of minimally invasive testing methods, potentially guiding diagnosis and detection of endometrial cancer in high-risk women and in cancer screening programs.

630The new proteomic-based point-of-care (POC) urine NMP22-bladder.chek® compared to the standard NMP22-elisa urine lab test for bladder cancer detection

2005 ◽  
Vol 4 (3) ◽  
pp. 160
Author(s):  
S. Hautmann ◽  
N. Filippow ◽  
P. Braun ◽  
H. Ellinghausen ◽  
M. Friedrich ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Detection ◽  
Point Of Care ◽  
Lab Test

Analytical sensitivity and stability of DNA methylation testing in stool samples for colorectal cancer detection

2012 ◽  
Vol 35 (4) ◽  
pp. 309-315 ◽  
Author(s):  
Linda J. W. Bosch ◽  
Sandra Mongera ◽  
Jochim S. Terhaar sive Droste ◽  
Frank A. Oort ◽  
Sietze T. van Turenhout ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Dna Methylation ◽  
Cancer Detection ◽  
Analytical Sensitivity ◽  
Stool Samples
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