scholarly journals Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion

2017 ◽  
Vol 6 (6) ◽  
pp. 459-470 ◽  
Author(s):  
Fatou K. Ndiaye ◽  
Ana Ortalli ◽  
Mickaël Canouil ◽  
Marlène Huyvaert ◽  
Clara Salazar-Cardozo ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Insulin Secretion ◽  
Human Insulin ◽  
Functional Assessment ◽  
Susceptibility Genes ◽  
Diabetes Susceptibility ◽  
New Genes

scholarly journals α-CGRP disrupts amylin fibrillization and regulates insulin secretion: implications on diabetes and migraine

2021 ◽  
Vol 12 (16) ◽  
pp. 5853-5864
Author(s):  
Amber L. H. Gray ◽  
Aleksandra Antevska ◽  
Benjamin A. Link ◽  
Bryan Bogin ◽  
Susan J. Burke ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Insulin Secretion ◽  
Protective Effect ◽  
Human Insulin ◽  
Human Amylin

CGRP concentration is elevated in migraine conditions. The protective effect of migraine against type 2 diabetes is attributed to the ability of CGRP to remodel human amylin aggregation and to suppress the secretion of mouse insulin 2 (the orthologue of human insulin).

scholarly journals Genomewide Search for Type 2 Diabetes Susceptibility Genes in Four American Populations

2000 ◽  
Vol 66 (6) ◽  
pp. 1871-1881 ◽  
Author(s):  
Margaret Gelder Ehm ◽  
Maha C. Karnoub ◽  
Hakan Sakul ◽  
Kirby Gottschalk ◽  
Donald C. Holt ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Susceptibility Genes ◽  
Diabetes Susceptibility

scholarly journals Search for type 2 diabetes susceptibility genes on chromosomes 1q, 3q and 12q

2008 ◽  
Vol 53 (4) ◽  
pp. 314-324 ◽  
Author(s):  
F. Takeuchi ◽  
Y. Ochiai ◽  
M. Serizawa ◽  
K. Yanai ◽  
N. Kuzuya ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Susceptibility Genes ◽  
Diabetes Susceptibility

scholarly journals Use of preclinical models to identify markers of type 2 diabetes susceptibility and novel regulators of insulin secretion – A step towards precision medicine

2019 ◽  
Vol 27 ◽  
pp. S147-S154 ◽  
Author(s):  
Bernard Thorens ◽  
Ana Rodriguez ◽  
Céline Cruciani-Guglielmacci ◽  
Leonore Wigger ◽  
Mark Ibberson ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Insulin Secretion ◽  
Precision Medicine ◽  
Preclinical Models ◽  
Diabetes Susceptibility
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