Preparation, in vitro mineralization and osteoblast cell response of electrospun 13–93 bioactive glass nanofibers

The biocompatibility and the antibacterial capability of meso-macroporous bioactive glass scaffolds in the SiO2–CaO–P2O5–ZnO system were investigated. Zn2+ ions release greatly influenced the osteoblast cell development and provides antibacterial capability against S. aureus.

Download Full-text

Flexible organic–inorganic hybrid bioceramic for bone tissue regeneration

Journal of Advanced Dielectrics ◽

10.1142/s2010135x20500137 ◽

2020 ◽

Vol 10 (04) ◽

pp. 2050013

Author(s):

Jing Chen ◽

Xingmei Zhang ◽

Beibei Li ◽

Yawei Yang

Keyword(s):

Simulated Body Fluid ◽

Bioactive Glass ◽

Tissue Regeneration ◽

Body Fluid ◽

Bone Tissue Regeneration ◽

Osteoblast Cell ◽

Butylene Succinate ◽

Inorganic Hybrid ◽

Cell Biocompatibility

Development of novel biomaterials for bone regeneration is based on the sufficient bone-bonding ability, bioactivity and biocompatibility. In this study, novel flexible poly(butylene succinate)/polydimethysiloxane-modified bioactive glass/nano-hydroxyapatite (PBSu/PDMS-BG/nHA) hybrid bioceramic with various nHA concentration on the in vitro bone-like hydroxyapatite (HA) formation, biomineralization activity and osteoblast cell biocompatibility were investigated. The rapid precipitation of HA on the hybrid bioceramic surfaces was found after being immersed in simulated body fluid (SBF) for seven days. Results show that the amount of HA deposition increased with the increase of nHA concentration. The optimized PBSu/PDMS-BG/nHA hybrid bioceramic exhibited good flexibility, high biomineralization activity and good osteoblast cell biocompatibility.

Download Full-text

Fabrication of dual drug loaded bilayered chitosan based composite scaffolds as osteochondral substitutes and evaluation of in vitro cell response using the MC3T3 pre-osteoblast cell line

Cellulose ◽

10.1007/s10570-019-02915-x ◽

2019 ◽

Vol 27 (4) ◽

pp. 2253-2266

Author(s):

Muhammad Samie ◽

Muhammad Arfat Yameen ◽

Hafiza Fakhera Ikram ◽

Haffsah Iqbal ◽

Aqif Anwar Chaudhry ◽

...

Keyword(s):

Cell Line ◽

Cell Response ◽

Osteoblast Cell ◽

Composite Scaffolds ◽

Osteoblast Cell Line ◽

Dual Drug

Download Full-text

In vitro endothelial cell response to ionic dissolution products from boron-doped bioactive glass in the SiO2–CaO–P2O5–Na2O system

Journal of Materials Chemistry B ◽

10.1039/c4tb01043d ◽

2014 ◽

Vol 2 (43) ◽

pp. 7620-7630 ◽

Cited By ~ 47

Author(s):

Luis A. Haro Durand ◽

Adrián Góngora ◽

José M. Porto López ◽

Aldo R. Boccaccini ◽

M. Paola Zago ◽

...

Keyword(s):

Endothelial Cell ◽

Regenerative Medicine ◽

Bioactive Glass ◽

Cell Response ◽

Bioactive Glasses ◽

Therapeutic Alternative ◽

Boron Doped ◽

System P ◽

Endothelial Cell Response

As it has been established that boron (B) may perform functions in angiogenesis and osteogenesis, the controlled and localized release of B ions from bioactive glasses (BGs) is expected to provide a promising therapeutic alternative for regenerative medicine of vascularized tissues, such as bone.

Download Full-text