In vitro and in vivo evaluation of anti-cancer activity: Shape-dependent properties of TiO 2 nanostructures

2017 ◽  
Vol 78 ◽  
pp. 969-977 ◽  
Author(s):  
T. Sree Latha ◽  
Madhava C. Reddy ◽  
Shankar V. Muthukonda ◽  
Vadali V.S.S. Srikanth ◽  
Dakshayani Lomada
Keyword(s):  
In Vivo Evaluation ◽  
Anti Cancer ◽  
Cancer Activity

scholarly journals GREEN SYNTHESIS AND CHARACTERIZATION OF ISOLATED FLAVONOID MEDIATED COPPER NANOPARTICLES BY USING THESPESIA POPULNEA LEAF EXTRACT AND ITS EVALUATION OF ANTI-OXIDANT AND ANTI-CANCER ACTIVITY

2022 ◽  
pp. 15-32
Author(s):  
MARIMUTHU GOKUL ◽  
UMARANI G. ◽  
AYYAMPERUMAL ESAKKI
Keyword(s):  
Green Synthesis ◽  
Cell Line ◽  
Reducing Power ◽  
Nano Particles ◽  
In Vivo Evaluation ◽  
Anti Cancer ◽  
Cancer Activity ◽  
Mcf 7

Objective: An Eco-friendly process of Green Synthesis of Copper Nano-particles (CuNPs) is an important aspect in the field of Nanotechnology using alternative feedstock, energy minimization, the design of less toxic and inherently safer chemicals. Methods: In this study, Copper Nano-Particles were synthesized by using isolated flavonoids to induce the reduction of Cu2+ions to CuNPs and also act as a capping and stabilizing agent. The solutions of CuSO4 and flavonoid were used as stock solutions for the preparation of CuNPs. Aqueous flavonoid(Quercetin) solution was mixed with CuSO4 solution separately. The reaction mixtures were immediately placed in a hot plate magnetic stirrer at 2000 rpm, 50-60 °C temperature and observed the change in colour of the solution from colourless to coloured solution. The synthesized CuNPs were characterized by various spectral methods for structural analysis of Nano-particles and In vitro and In vivo evaluation for anti-cancer activity. Results: The results described that the Copper Nano-particles are crystalline and amorphous with an average size of 295.4 nm and highly stable and having good hydrogen peroxide scavenging effect, reducing power and total antioxidant activity with the IC50value of 59.24μg/ml, 24.35μg/ml and16.83μg/ml respectively. The in vitro (HepG2 and MCF-7 cell lines) anti-cancer activity showing good results with IC50 values of 57.56 µg/ml for HepG2 cell line and 56.41 µg/ml for MCF-7 cell line. The in vivo anti-cancer activity also showing good results.

scholarly journals Evaluation of the anti-cancer activity of the triterpenoidal saponin fraction isolated from the traditional Chinese medicine Conyza blinii H. Lév.

RSC Advances ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 3408-3412 ◽  
Author(s):  
Long Ma ◽  
Haiyan Liu ◽  
Lingpei Meng ◽  
Ping Qin ◽  
Botao Zhang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Anti Cancer ◽  
Saponin Fraction ◽  
Cancer Activity

Triterpenoidal saponins fraction isolated from a traditional Chinese medicine Conyza blinii H. Lév. demonstrates anti-cancer activity both in vitro and in vivo.

Calycosin-loaded nanostructured lipid carriers: In-vitro and in-vivo evaluation for enhanced anti-cancer potential

2021 ◽  
pp. 102957
Author(s):  
Shumaila Arshad ◽  
Masood-Ur-Rehman ◽  
Mulazim Hussain Asim ◽  
Arshad Mahmood ◽  
Muhammad Ijaz ◽  
...  
Keyword(s):  
Nanostructured Lipid Carriers ◽  
In Vivo Evaluation ◽  
Anti Cancer

Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro

2020 ◽  
Vol 160 ◽  
pp. 496-505 ◽  
Author(s):  
Jun Wang ◽  
Lijun Wang ◽  
Shuhong Zhang ◽  
Junting Fan ◽  
Hui Yang ◽  
...  
Keyword(s):  
Protein Interaction ◽  
Protein Protein Interaction ◽  
Anti Cancer ◽  
Cancer Activity

scholarly journals Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Alexander J. Stevenson ◽  
Eleanor I. Ager ◽  
Martina A. Proctor ◽  
Dubravka Škalamera ◽  
Andrew Heaton ◽  
...  
Keyword(s):  
Mechanism Of Action ◽  
Third Generation ◽  
The Third ◽  
Anti Cancer ◽  
Cancer Activity

scholarly journals Phospho-ibuprofen (MDC-917) incorporated in nanocarriers: anti-cancer activity in vitro and in vivo

2012 ◽  
Vol 166 (3) ◽  
pp. 991-1001 ◽  
Author(s):  
T Nie ◽  
CC Wong ◽  
N Alston ◽  
P Aro ◽  
PP Constantinides ◽  
...  
Keyword(s):  
Anti Cancer ◽  
Cancer Activity

In vitro and in vivo anti-cancer activity of tangeretin against colorectal cancer was enhanced by emulsion-based delivery system

2015 ◽  
Vol 15 ◽  
pp. 264-273 ◽  
Author(s):  
Yuwen Ting ◽  
Yi-Shiou Chiou ◽  
Min-Hsiung Pan ◽  
Chi-Tang Ho ◽  
Qingrong Huang
Keyword(s):  
Colorectal Cancer ◽  
Delivery System ◽  
Anti Cancer ◽  
Cancer Activity

Synthesis, in vitro, and in vivo evaluation of novel functionalized quaternary ammonium curcuminoids as potential anti-cancer agents

2015 ◽  
Vol 25 (24) ◽  
pp. 5777-5780 ◽  
Author(s):  
Lucas N. Solano ◽  
Grady L. Nelson ◽  
Conor T. Ronayne ◽  
Erica A. Lueth ◽  
Melissa A. Foxley ◽  
...  
Keyword(s):  
Quaternary Ammonium ◽  
In Vivo Evaluation ◽  
Anti Cancer

scholarly journals Hydroquinone Exhibits In Vitro and In Vivo Anti-Cancer Activity in Cancer Cells and Mice

2018 ◽  
Vol 19 (3) ◽  
pp. 903 ◽  
Author(s):  
Se Byeon ◽  
Young-Su Yi ◽  
Jongsung Lee ◽  
Woo Yang ◽  
Ji Kim ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Anti Cancer ◽  
Cancer Activity
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