Inulin Coated Mn3O4 Nanocuboids Coupled with RNA Interference Reverse Intestinal Tumorigenesis in Apc Knockout Murine Colon Cancer Models

2021 ◽  
pp. 102504
Author(s):  
Khushboo Kourani ◽  
Poonam Jain ◽  
Aviral Kumar ◽  
Ashok Kumar Jangid ◽  
Guruprasadh Swaminathan ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Rna Interference ◽  
Intestinal Tumorigenesis ◽  
Cancer Models ◽  
Murine Colon

scholarly journals Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models

2007 ◽  
Vol 12 (1) ◽  
pp. 330-342 ◽  
Author(s):  
Hala Gali-Muhtasib ◽  
Matthias Ocker ◽  
Doerthe Kuester ◽  
Sabine Krueger ◽  
Zeina El-Hajj ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Tumor Growth ◽  
Tumor Cell ◽  
Cell Invasion ◽  
Tumor Cell Invasion ◽  
Colon Tumor ◽  
Mouse Colon ◽  
Cancer Models ◽  
Colon Tumor Cell ◽  
Murine Colon

scholarly journals PD-L1 Targeting Immune-Microbubble Complex Enhances Therapeutic Index in Murine Colon Cancer Models

2020 ◽  
Vol 14 (1) ◽  
pp. 6
Author(s):  
Daehyun Kim ◽  
Seung Soo Lee ◽  
Hyungwon Moon ◽  
So Yeon Park ◽  
Hak Jong Lee
Keyword(s):  
Cancer Immunotherapy ◽  
Focused Ultrasound ◽  
Therapeutic Potential ◽  
Checkpoint Inhibitors ◽  
Therapeutic Index ◽  
Treatment Regimens ◽  
Cancer Models ◽  
Programmed Death ◽  
Murine Colon ◽  
Cell Death Protein

Cancer immunotherapy has revolutionized the way different neoplasms are treated. Among the different variations of cancer immunotherapy, the checkpoint inhibitors targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis have been validated and are currently used in the clinics. Nevertheless, these therapeutic antibodies are associated with significant side effects and are known to induce immune-related toxicities. To address these issues, we have developed an immune-microbubble complex (IMC) which not only reduces the toxicities associated with the antibodies but also enhances the therapeutic efficacy when combined with focused ultrasound. The concept of IMCs could be applied to any type of antibody-based treatment regimens to maximize their therapeutic potential.

scholarly journals Non-viral immune electrogene therapy induces potent antitumour responses and has a curative effect in murine colon adenocarcinoma and melanoma cancer models

Gene Therapy ◽  
2014 ◽  
Vol 22 (1) ◽  
pp. 29-39 ◽  
Author(s):  
P F Forde ◽  
L J Hall ◽  
M de Kruijf ◽  
M G Bourke ◽  
T Doddy ◽  
...  
Keyword(s):  
Colon Adenocarcinoma ◽  
Curative Effect ◽  
Melanoma Cancer ◽  
Cancer Models ◽  
Murine Colon

Schedule-dependent synergistic effects of 5-fluorouracil and selumetinib in KRAS or BRAF mutant colon cancer models

2019 ◽  
Vol 160 ◽  
pp. 110-120 ◽  
Author(s):  
Hye Yeon Jang ◽  
Do Hyung Kim ◽  
Haeng Jung Lee ◽  
Won Dong Kim ◽  
Seog-Young Kim ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Synergistic Effects ◽  
Cancer Models ◽  
Braf Mutant

scholarly journals {Ru(CO)x}-Core complexes with benzimidazole ligands: synthesis, X-ray structure and evaluation of anticancer activity in vivo

2017 ◽  
Vol 46 (9) ◽  
pp. 3025-3040 ◽  
Author(s):  
Gabriella Tamasi ◽  
Antonello Merlino ◽  
Federica Scaletti ◽  
Petra Heffeter ◽  
Anton A. Legin ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Anticancer Activity ◽  
Antitumor Effects ◽  
X Ray ◽  
Murine Colon

fac-[RuII(CO)3Cl2(MBI)] and -[RuII(CO)3Cl2(DMBI)] are CO-releasing materials able to link histidines of proteins, and the latter showed antitumor effects in murine colon cancer.

Combinatorial therapy using RNAi and curcumin nano-architectures regresses tumors in breast and colon cancer models

Nanoscale ◽  
2022 ◽  
Author(s):  
Aviral Kumar ◽  
Amarnath Singam ◽  
Guruprasadh Swaminathan ◽  
Naresh Killi ◽  
Naveen Kumar Tangudu ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Colorectal Cancers ◽  
Murine Models ◽  
Combinatorial Therapy ◽  
Cancer Models ◽  
S 100 ◽  
Eudragit S 100

This novel combination of curcumin (CU)–chitosan (CS) nanocomposites conjugated to Ephb4 shRNA encapsulated with Eudragit S-100 (ES) has been developed to combat breast and colorectal cancers murine models.

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