Human dorsomedial prefrontal cortex delineates the self and other against the tendency to form interdependent social representations

Neuron ◽  
2021 ◽  
Vol 109 (14) ◽  
pp. 2209-2211
Author(s):  
Sunhae Sul ◽  
M. Justin Kim
Keyword(s):  
Prefrontal Cortex ◽  
Social Representations ◽  
The Self ◽  
Self And Other ◽  
Dorsomedial Prefrontal Cortex

scholarly journals The dorsomedial prefrontal cortex computes task-invariant relative subjective value for self and other

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Matthew Piva ◽  
Kayla Velnoskey ◽  
Ruonan Jia ◽  
Amrita Nair ◽  
Ifat Levy ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Neural Correlates ◽  
Risky Choice ◽  
Behavioral Modeling ◽  
Self And Other ◽  
Dorsomedial Prefrontal Cortex ◽  
Subjective Value ◽  
Neural Computations ◽  
Decoding Accuracy ◽  
Independent Tasks

Few studies have addressed the neural computations underlying decisions made for others despite the importance of this ubiquitous behavior. Using participant-specific behavioral modeling with univariate and multivariate fMRI approaches, we investigated the neural correlates of decision-making for self and other in two independent tasks, including intertemporal and risky choice. Modeling subjective valuation indicated that participants distinguished between themselves and others with dissimilar preferences. Activity in the dorsomedial prefrontal cortex (dmPFC) and ventromedial prefrontal cortex (vmPFC) was consistently modulated by relative subjective value. Multi-voxel pattern analysis indicated that activity in the dmPFC uniquely encoded relative subjective value and generalized across self and other and across both tasks. Furthermore, agent cross-decoding accuracy between self and other in the dmPFC was related to self-reported social attitudes. These findings indicate that the dmPFC emerges as a medial prefrontal node that utilizes a task-invariant mechanism for computing relative subjective value for self and other.

scholarly journals Themata in science and in common sense

2017 ◽  
Vol 19 (1) ◽  
pp. 68-92 ◽  
Author(s):  
Ivana Marková
Keyword(s):  
Common Sense ◽  
Social Representations ◽  
Social Practices ◽  
The Self ◽  
Scientific Thinking ◽  
Scientific Theories ◽  
Self And Other ◽  
Human Thinking ◽  
Theory Of Social Representations

AbstractHuman thinking is heterogeneous, and among its different forms, thinking in dyadic oppositions is associated with the concept of themata. Gerald Holton characterises themata as elements that lie beneath the structure and development of physical theories as well as of non-scientific thinking. Themata have different uses, such as a thematic concept, or a thematic component of the concept; a methodological (or epistemological) thema; and a propositional thema. Serge Moscovici has placed the concept of themata in the heart of his theory of social representations which is based on ‘natural thinking’ and on forms of daily knowing, including common sense. In this article I shall explore some features of thematic concepts and of methodological themata in scientific theories and in common sense. More specifically, I shall refer to the significance of the methodological (or epistemological) thema the Self and Other(s) in common-sense thinking and in social practices.

Is the self special in the dorsomedial prefrontal cortex? An fMRI study

2009 ◽  
Vol 4 (5) ◽  
pp. 455-463 ◽  
Author(s):  
Ken Yaoi ◽  
Naoyuki Osaka ◽  
Mariko Osaka
Keyword(s):  
Prefrontal Cortex ◽  
The Self ◽  
Dorsomedial Prefrontal Cortex ◽  
Fmri Study

Accounts of consent: Orienting to self-other relations regarding motivations to participate in cancer bio-banking

2015 ◽  
Vol 11 (1) ◽  
pp. 69-84 ◽  
Author(s):  
Hannah Shipman ◽  
Srikant Sarangi ◽  
Angus J. Clarke
Keyword(s):  
Reflective Practice ◽  
Extreme Case ◽  
The Self ◽  
Case Formulation ◽  
Contrast Structure ◽  
Self And Other ◽  
Clinical Encounters ◽  
Rhetorical Discourse ◽  
Motivation To Participate ◽  
Significant Factors

The motivations of those who give consent to bio-banking research have received a great deal of attention in recent years. Previous work draws upon the notion of altruism, though the self and/or family have been proposed as significant factors. Drawing on 11 interviews with staff responsible for seeking consent to cancer bio-banking and 13 observations of staff asking people to consent in routine clinical encounters, we investigate how potential participants are oriented to, and constructed as oriented to, self and other related concerns (Author 2007). We adopt a rhetorical discourse analytic approach to the data and our perspective can be labelled as ‘ethics-in-interaction’. Using analytic concepts such as repetition, extreme case formulation, typical case formulation and contrast structure, our observations are three-fold. Firstly, we demonstrate that orientation to ‘general others’ in altruistic accounts and to ‘self’ in minimising burden are foregrounded in constructions of motivation to participate in cancer bio-banking across the data corpus. Secondly, we identify complex relational accounts which involve the self as being more prominent in the consent encounter data where the staff have a nursing background whereas ‘general others’ feature more when the staff have a scientific background. Finally, we suggest implications based on the disparities between how participants are oriented in interviews and consent encounters which may have relevance for developing staff’s reflective practice.

Self–Other Knowledge Asymmetry (SOKA) Model

2020 ◽  
Author(s):  
Kathryn L. Bollich-Ziegler
Keyword(s):  
Personality Traits ◽  
The Self ◽  
Multiple Perspectives ◽  
Self Perception ◽  
Self And Other ◽  
Self Perceptions ◽  
Self Reports ◽  
Knowledge Asymmetry ◽  
Blind Spots

Despite the strong intuition that people know themselves well, much research in self-perception demonstrates the biases present when evaluating one’s own personality traits. What specifically are these blind spots in self-perceptions? Are self-perceptions always disconnected from reality? And under what circumstances might other people actually be more accurate about the self? The self–other knowledge asymmetry (SOKA) model suggests that because individuals and others differ in their susceptibility to biases or motivations and in the information they have access to, self- and other-knowledge will vary by trait. The present chapter outlines when and why other-perceptions are sometimes more accurate than self-perceptions, as well as when self-reports can be most trusted. Also discussed are next steps in the study of self- and other-knowledge, including practical, methodological, and interdisciplinary considerations and extensions. In sum, this chapter illustrates the importance of taking multiple perspectives in order to accurately understand a person.

scholarly journals A pilot trial of repetitive transcranial magnetic stimulation of the dorsomedial prefrontal cortex in anorexia nervosa: resting fMRI correlates of response

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
D. Blake Woodside ◽  
Katharine Dunlop ◽  
Charlene Sathi ◽  
Eileen Lam ◽  
Brigitte McDonald ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Prefrontal Cortex ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Trial Registration ◽  
Angular Gyrus ◽  
Open Label ◽  
Compulsive Disorder ◽  
Dorsomedial Prefrontal Cortex

Abstract Background Patients with anorexia nervosa (AN) face severe and chronic illness with high mortality rates, despite our best currently available conventional treatments. Repetitive transcranial magnetic stimulation (rTMS) has shown increasing efficacy in treatment-refractory cases across a variety of psychiatric disorders comorbid with AN, including major depression, Obsessive Compulsive Disorder (OCD), and Post traumatic Stress Disorder (PTSD). However, to date few studies have examined the effects of a course of rTMS on AN pathology itself. Methods Nineteen patients with AN underwent a 20–30 session open-label course of dorsomedial prefrontal rTMS for comorbid Major Depressive Disorder (MDD) ± PTSD. Resting-state functional MRI was acquired at baseline in 16/19 patients. Results Following treatment, significant improvements were seen in core AN pathology on the EDE global scale, and to a lesser extent on the shape and weight concerns subscales. Significant improvements in comorbid anxiety, and to a lesser extent depression, also ensued. The greatest improvements were seen in patients with lower baseline functional connectivity from the dorsomedial prefrontal cortex (DMPFC) target to regions in the right frontal pole and left angular gyrus. Conclusions Despite the limited size of this preliminary, open-label study, the results suggest that rTMS is safe in AN, and may be useful in addressing some core domains of AN pathology. Other targets may also be worth studying in this population, in future sham-controlled trials with larger sample sizes. Trial registration Trial registration ClinicalTrials.gov NCT04409704. Registered May 282,020. Retrospectively registered.

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