O40. Nitric oxide signalling leading to altered gene expression and oxidative stress resistance involves a zinc-dependent activation of transcription factors nrf-2 and MTF-1

Nitric Oxide ◽  
2006 ◽  
Vol 14 (4) ◽  
pp. 12-13 ◽  
Author(s):  
Miriam M. Cortese ◽  
Christoph V. Suschek ◽  
Victoria Kolb-Bachofen
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Nitric Oxide ◽  
Transcription Factors ◽  
Stress Resistance ◽  
Oxidative Stress Resistance ◽  
Altered Gene Expression ◽  
Activation Of Transcription ◽  
Altered Gene ◽  
And Oxidative Stress

scholarly journals Altered Gene Expression, Mitochondrial Damage and Oxidative Stress: Converging Routes in Motor Neuron Degeneration

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Luisa Rossi ◽  
Cristiana Valle ◽  
Maria Teresa Carrì
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Motor Neuron ◽  
Motor Neurons ◽  
Mitochondrial Damage ◽  
Energy Deficit ◽  
Control Of Gene Expression ◽  
Altered Gene Expression ◽  
Altered Gene ◽  
And Oxidative Stress

Motor neuron diseases (MNDs) are a rather heterogeneous group of diseases, with either sporadic or genetic origin or both, all characterized by the progressive degeneration of motor neurons. At the cellular level, MNDs share features such as protein misfolding and aggregation, mitochondrial damage and energy deficit, and excitotoxicity and calcium mishandling. This is particularly well demonstrated in ALS, where both sporadic and familial forms share the same symptoms and pathological phenotype, with a prominent role for mitochondrial damage and resulting oxidative stress. Based on recent data, however, altered control of gene expression seems to be a most relevant, and previously overlooked, player in MNDs. Here we discuss which may be the links that make pathways apparently as different as altered gene expression, mitochondrial damage, and oxidative stress converge to generate a similar motoneuron-toxic phenotype.

Functional characterization of a mycothiol peroxidase in Corynebacterium glutamicum that uses both mycoredoxin and thioredoxin reducing systems in the response to oxidative stress

2015 ◽  
Vol 469 (1) ◽  
pp. 45-57 ◽  
Author(s):  
Meiru Si ◽  
Yixiang Xu ◽  
Tietao Wang ◽  
Mingxiu Long ◽  
Wei Ding ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Corynebacterium Glutamicum ◽  
Stress Resistance ◽  
Functional Characterization ◽  
Gram Positive ◽  
Oxidative Stress Resistance ◽  
Proton Donors ◽  
New Type ◽  
And Oxidative Stress

Mycothiol peroxidase, a new type of GSH peroxidase distributed in GSH-lacking high-(G+C)-content Gram-positive actinobacteria, uses both mycoredoxin and thioredoxin systems as proton donors for regeneration and oxidative stress resistance.

scholarly journals Cyanobacterial Mn-catalase ‘KatB’: Molecular link between salinity and oxidative stress resistance

2016 ◽  
Vol 9 (5) ◽  
pp. e1216738 ◽  
Author(s):  
Dhiman Chakravarty ◽  
Manisha Banerjee ◽  
Namrata Waghmare ◽  
Anand Ballal
Keyword(s):  
Oxidative Stress ◽  
Stress Resistance ◽  
Oxidative Stress Resistance ◽  
And Oxidative Stress
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