Otoliths/Bacterial Cellulose Nanocomposite as a Potential Dental Pulp Capping Biomaterial in Canine Model

2015 ◽  
Vol 120 (2) ◽  
pp. e105 ◽  
Author(s):  
JULIANA BATISTA MELO DA FONTE ◽  
DAISY PEREIRA VALIDO ◽  
LAURO XAVIER FILHO ◽  
LIGIA MARIA MANZINE COSTA ◽  
GABRIEL MOLINA DE OLYVEIRA ◽  
...  
Keyword(s):  
Bacterial Cellulose ◽  
Dental Pulp ◽  
Canine Model ◽  
Pulp Capping ◽  
Dental Pulp Capping

Novel Otoliths/Bacterial Cellulose Nanocomposites as a Potential Natural Product for Direct Dental Pulp Capping

2012 ◽  
Vol 2 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Ligia Maria Manzine Costa ◽  
Gabriel Molina de Olyveira ◽  
Pierre Basmaji ◽  
Daisy Pereira Valido ◽  
Plácia Barreto Prata Gois ◽  
...  
Keyword(s):  
Natural Product ◽  
Bacterial Cellulose ◽  
Dental Pulp ◽  
Pulp Capping ◽  
Dental Pulp Capping ◽  
Cellulose Nanocomposites

scholarly journals Materiais Utilizados para Capeamento Pulpar Direto: uma Revisão da Literatura

2018 ◽  
Vol 19 (5) ◽  
pp. 209
Author(s):  
C M A Silva ◽  
L S Paiva ◽  
D V Oliveira ◽  
B O Nobre ◽  
T A D Mendes ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Dental Pulp ◽  
Biocompatible Materials ◽  
Pulp Capping ◽  
Dental Pulp Capping

O objetivo deste estudo é avaliar as propriedades físico-químicas e biológicas dos principais materiais indicados para capeamento pulpar direto. Revisou-se a literatura, nos bancos de dados Pubmed, Scopus e Scielo, entre 2007 e 2017, buscando artigos em português e em inglês, utilizando os descritores combinados: “Dental Pulp Capping”, “Biocompatible Materials” e “Calcium Hydroxide” como estratégia de busca. Foram obtidos 55 artigos em que 21 estavam em repetição e foram excluídos, dos demais 6 eram revisão de literatura, 3 eram ensaios clínicos e 25 estudos laboratoriais. Através de uma leitura crítica dos títulos e dos resumos, foram selecionados 10 artigos segundo sua relevância para o estudo. Os materiais mais relatados foram o hidróxido de cálcio, o agregado trióxido mineral (MTA) e o silicato tricálcio (biodentine®). O primeiro contém propriedades antibacterianas e biocompatibilidade, entretanto possui a sua alta solubilidade como desvantagem. O segundo apresenta resultados mais previsíveis que o primeiro na formação da barreira dentinária, melhor biocompatibilidade e boa capacidade seladora. O terceiro mostra maior formação de dentina terciária, promovendo um bom selamento marginal e mostra a menor solubilidade entre eles. Assim, os materiais MTA e biodentine mostram-se materiais viáveis ao tradicional hidróxido de cálcio.Palavras-chave: Dental Pulp Capping. Biocompatible Materials. Calcium Hydroxide. 

scholarly journals Evaluation of Resin-Based Material Containing Copaiba Oleoresin (Copaifera Reticulata Ducke): Biological Effects on the Human Dental Pulp Stem Cells

Biomolecules ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 972
Author(s):  
Roberta Souza D’Almeida Couto ◽  
Maria Fernanda Setubal Destro Rodrigues ◽  
Leila Soares Ferreira ◽  
Ivana Márcia Alves Diniz ◽  
Fernando de Sá Silva ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Biological Effects ◽  
Dental Pulp Stem Cells ◽  
Nodule Formation ◽  
Alizarin Red ◽  
Pulp Capping ◽  
Hsp 27 ◽  
Dental Pulp Capping ◽  
Human Dental Pulp

The purpose of this study was to analyze in vitro the biological effects on human dental pulp stem cells triggered in response to substances leached or dissolved from two experimental cements for dental pulp capping. The experimental materials, based on extracts from Copaifera reticulata Ducke (COP), were compared to calcium hydroxide [Ca(OH)2] and mineral trioxide aggregate (MTA), materials commonly used for direct dental pulp capping in restorative dentistry. For this, human dental pulp stem cells were exposed to COP associated or not with Ca(OH)2 or MTA. Cell cytocompatibility, migration, and differentiation (mineralized nodule formation (Alizarin red assay) and gene expression (RT-qPCR) of OCN, DSPP, and HSP-27 (genes regulated in biomineralization events)) were evaluated. The results showed that the association of COP reduced the cytotoxicity of Ca(OH)2. Upregulations of the OCN, DSPP, and HSP-27 genes were observed in response to the association of COP to MTA, and the DSPP and HSP-27 genes were upregulated in the Ca(OH)2 + COP group. In up to 24 h, cell migration was significantly enhanced in the MTA + COP and Ca(OH)2 + COP groups. In conclusion, the combination of COP with the currently used materials for dental pulp capping [Ca(OH)2 and MTA] improved the cell activities related to pulp repair (i.e., cytocompatibility, differentiation, mineralization, and migration) including a protective effect against the cytotoxicity of Ca(OH)2.

scholarly journals Evaluation of pH changes produced by dental pulp capping materials: An in vitro study

2017 ◽  
Vol 54 (2) ◽  
pp. 161-165
Author(s):  
Elzbieta Luczaj-Cepowicz ◽  
Grazyna Marczuk-Kolada ◽  
Malgorzata Pawinska ◽  
Marta Obidzinska
Keyword(s):  
Dental Pulp ◽  
In Vitro Study ◽  
Vitro Study ◽  
Pulp Capping ◽  
Ph Changes ◽  
Dental Pulp Capping

NOS Evaluations in Human Dental Pulp-Capping with MTA and Calcium-Hydroxide

2007 ◽  
Vol 20 (1_suppl) ◽  
pp. 27-32 ◽  
Author(s):  
C. D'arcangelo ◽  
F. Di Nardo-Di Maio ◽  
C. Patrono ◽  
S. Caputi
Keyword(s):  
Calcium Hydroxide ◽  
Dental Pulp ◽  
Pulp Capping ◽  
Dental Pulp Capping ◽  
Human Dental Pulp

scholarly journals Combinations of propolis and Ca(OH)2 in dental pulp capping treatment for the stimulation of reparative dentin formation in a rat model

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 308 ◽  
Author(s):  
Retno Pudji Rahayu ◽  
Nirawati Pribadi ◽  
Ira Widjiastuti ◽  
Nur Ariska Nugrahani
Keyword(s):  
Treatment Group ◽  
Dental Pulp ◽  
Tissue Repair ◽  
Treatment Process ◽  
Pulp Tissue ◽  
Treatment Groups ◽  
Pulp Capping ◽  
Reparative Dentin ◽  
Dental Pulp Capping ◽  
Dentin Formation

Background: Caries in the dental pulp result in inflammation and damage to the pulp tissue. During inflammation of the pulp, various inflammatory mediators and growth factors are released, including IL-8, IL-10, TLR-2, VEGF and TGF-β through the NF-kB pathway. In the present study, therapy for pulpal caries was performed through pulp capping by giving a combination of propolis and calcium hydroxide (Ca(OH)2). This treatment was expected to stimulate the formation of reparative dentin as an anti-inflammatory material to prevent pulp tissue damage. Methods: 28 Wistar rats were divided into four groups and treated with Ca(OH)2 with or without the addition of propolis for either 7 or 14 days. Immunohistochemical examination was used to determine the expression of IL-8, IL-10, TLR-2, VEGF, TGF-β in the four treatment groups. Results: The group treated with a combination of propolis and Ca(OH)2 for 7 days showed that the expression of IL-10, IL-8, TLR-2, VEGF, TGF-β increased significantly compared to the treatment group treated with only Ca(OH)2. The expression of IL-10, TLR-2, TGF-β, VEGF increased in the treatment group treated with propolis and Ca(OH)2 for 14 days, while the expression of IL-8 in the decreased significantly. Conclusions: Administration of a combination of propolis and Ca(OH)2 has efficacy in the pulp capping treatment process because it has anti-bacterial and immunomodulatory properties. The results show that it is able to stimulate the process of pulp tissue repair through increased expression of IL-10, TGF-β, VEGF, TLR -2 and decreased expression of IL-8.

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