Pleomorphic Adenoma of Minor Salivary Glands: a Case Report

Introduction. Although pleomorphic adenoma is the most common neoplasm of the salivary glands, this tumor most commonly involves the minor salivary glands of palatal and rarely occurs in cervical region.Case Report. A 21-year-old female referred to our clinic due to painless mass of right upper region of neck. After paraclinical and pathologic evaluation, it was diagnosed as cervical pleomorphic adenoma.Conclusion. Pleomorphic adenoma may be rarely involving the neck. Although the prognosis is good, the choice treatment is the complete resection of the tumor.

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A Giant Pleomorphic Adenoma of the Palatine Arch in a 75-Year-Old Man: A Case Report with Review of Literature

International Journal of Head and Neck Surgery ◽

10.5005/jp-journals-10001-1213 ◽

2015 ◽

Vol 6 (1) ◽

pp. 23-25

Author(s):

Santosh Kumar Swain ◽

Mahesh Chandra Sahu ◽

Rajashree Tripathy

Keyword(s):

Case Report ◽

Salivary Glands ◽

Pleomorphic Adenoma ◽

Soft Palate ◽

Benign Tumor ◽

Review Of Literature ◽

Minor Salivary Glands ◽

Common Benign Tumor ◽

Slow Growing ◽

Head Neck

ABSTRACT Pleomorphic adenoma (PA) is the most common benign tumor of the salivary glands and has both epithelial and mesenchymal tissues. It most commonly arises from the parotid or submandibular glands. Rarely, it arises from the minor salivary glands. We report here a case of pleomorphic adenoma arising from the soft palate and both sides of anterior tonsillar pillars in a 75-year-old man. This patient was presenting painless slow growing large swelling in the soft palate over 20 years causing mechanical obstruction of airway and food. The entire tumor mass was excised along with overlying mucosa. How to cite this article Swain SK, Sahu MC, Tripathy R. A Giant Pleomorphic Adenoma of the Palatine Arch in a 75-Year-Old Man: A Case Report with Review of Literature. Int J Head Neck Surg 2015;6(1):23-25.

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PLEOMORPHIC ADENOMA LEFT NOSE ALA IN 15 YRS OLD GIRL . A RARE CASE REPORT

10.36106/gjra/9101241 ◽

2021 ◽

pp. 33-34

Author(s):

Radhika Mucharla ◽

Praneeth kumar.K. ◽

Sumalatha Kasturi

Keyword(s):

Case Report ◽

Salivary Glands ◽

Pleomorphic Adenoma ◽

Soft Palate ◽

Rare Case ◽

Benign Tumor ◽

Minor Salivary Glands ◽

Common Benign Tumor ◽

Pleomorphic Adenomas ◽

Rare Case Report

Pleomorphic adenomas are the most common benign tumor of major salivary glands. In addition, they may also occur in 1 minor salivary glands of hard and soft palate . Intranasal 2 pleomorphic adenomas are unusual .

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Carcinoma ex pleomorphic adenoma in minor salivary glands of the anterior tongue: A case report

Journal of Oral and Maxillofacial Surgery Medicine and Pathology ◽

10.1016/j.ajoms.2012.08.010 ◽

2013 ◽

Vol 25 (2) ◽

pp. 197-200 ◽

Cited By ~ 1

Author(s):

Shin-ichi Yamada ◽

Souichi Yanamoto ◽

Satoshi Rokutanda ◽

Kouhei Matsutani ◽

Goro Kawasaki ◽

...

Keyword(s):

Case Report ◽

Salivary Glands ◽

Pleomorphic Adenoma ◽

Carcinoma Ex Pleomorphic Adenoma ◽

Minor Salivary Glands

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Polymorphous low-grade adenocarcinoma versus pleomorphic adenoma of minor salivary glands: Resolution of a diagnostic dilemma by immunohistochemical analysis with glial fibrillary acidic protein

Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology ◽

10.1067/moe.2001.111306 ◽

2001 ◽

Vol 91 (2) ◽

pp. 194-199 ◽

Cited By ~ 31

Author(s):

Alice E. Curran ◽

Dean K. White ◽

Douglas D. Damm ◽

Valerie A. Murrah

Keyword(s):

Glial Fibrillary Acidic Protein ◽

Salivary Glands ◽

Pleomorphic Adenoma ◽

Immunohistochemical Analysis ◽

Acidic Protein ◽

Low Grade ◽

Minor Salivary Glands ◽

Diagnostic Dilemma

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Myoepithelial Carcinoma ex Pleomorphic Adenoma: Rare Case Report with Clinicopathologic and Immunohistochemical Features

American Journal of Clinical Pathology ◽

10.1093/ajcp/aqab191.184 ◽

2021 ◽

Vol 156 (Supplement_1) ◽

pp. S86-S87

Author(s):

M Khazaeli ◽

Z Kamaluddin ◽

M Taherian

Keyword(s):

Case Report ◽

Parotid Gland ◽

Pleomorphic Adenoma ◽

Nasal Passage ◽

Carcinoma Ex Pleomorphic Adenoma ◽

Sublingual Gland ◽

Myoepithelial Carcinoma ◽

Minor Salivary Glands ◽

Myoepithelial Differentiation ◽

The Right

Abstract Introduction/Objective Myoepithelial carcinoma is identified by nearly exclusive myoepithelial differentiation and evidence of malignancy. It may arise de novo or in preexisting benign tumors including pleomorphic adenoma and benign myoepithelioma. It occurs most commonly in the parotid gland followed by submandibular glands, minor salivary glands, and occasionally in the sublingual gland. Nasopharyngeal origin has been rarely reported. Methods/Case Report An afebrile 19-year-old female presented to the emergency department with persistent facial pressure, otalgia (right side greater than left side), rhinorrhea, and several episodes of epistaxis. One month before, she has been treated with Amoxicillin for three days with no relief, where Augmentin started for her for five days. About four days prior presentation, she was placed on Prednisone and Cefdinir. Over the next several days, she began having throat pain with difficulty swallowing. Routine blood work revealed a leukocytosis of 14.2 with normal differentiation. CT of the neck showed a large soft tissue mass centered at the right nasopharynx. Flexible nasal endoscopy performed bilaterally to reveal the nasopharynx is entirely obstructed with a lobulated mass filling the nasopharynx. On the right side, it extends into the posterior nasal passage filling the sphenoethmoid recess and the posterior floor of the nasal passage. Outpatient biopsy from nasopharynx mass is also performed. Results (if a Case Study enter NA) Mass biopsy reveals a mucinous and chondromyxoid background with mixed epithelial and myoepithelial differentiation. The is squamous metaplasia of myoepithelial cells and prominent mitotic activity and apoptotic activity. Immunohistochemistry was positive for CK5/6, calponin, BCL2, SMA, BerEp4, Sox10, and a proliferative index up to 40%. Based on this information Myoepithelial Carcinoma ex-pleomorphic adenoma of the nasopharynx is the diagnosis. Conclusion Carcinoma ex pleomorphic adenoma is usually a high-grade malignancy. It occurs most commonly in the parotid gland, followed by submandibular glands, minor salivary glands, and occasionally in the sublingual gland. Our case is one of the few cases of myoepithelial carcinoma arising in nasopharyngeal pleomorphic adenoma.

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Mucoepidermoid Carcinoma of Palatal Minor Salivary Glands with Intracranial Extension: A Case Report and Literature Review

Journal of Neurological Surgery Reports ◽

10.1055/s-0036-1593396 ◽

2016 ◽

Vol 77 (04) ◽

pp. e156-e159 ◽

Cited By ~ 2

Author(s):

Rimal Dossani ◽

Hesam Akbarian-Tefaghi ◽

Lori Lemonnier ◽

Vikas Mehta ◽

Jamie Jacobsohn ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Salivary Glands ◽

Mucoepidermoid Carcinoma ◽

Intracranial Extension ◽

Minor Salivary Glands

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Synchronous pleomorphic adenoma in the infratemporal fossa and contralateral submandibular gland and endoscopic removal

BMJ Case Reports ◽

10.1136/bcr-2020-237775 ◽

2021 ◽

Vol 14 (5) ◽

pp. e237775

Author(s):

Shahul Hameed Poondiyar Sirajuddin ◽

Rayappa Chunnusamy

Keyword(s):

Salivary Glands ◽

Submandibular Gland ◽

Pleomorphic Adenoma ◽

Nasal Septum ◽

Infratemporal Fossa ◽

Endoscopic Removal ◽

Minor Salivary Glands ◽

Main Stem Bronchus ◽

Diagnostic Dilemma ◽

First Case

The objective of this article is to elucidate on our experience with the first case reported in the literature of a synchronous presentation of pleomorphic adenoma (PA) in infratemporal fossa as well as the contralateral submandibular gland. PA most commonly arises from the major salivary glands but has also been reported to arise from minor salivary glands in unusual sites such as the nasal septum, main stem bronchus, trachea, lacrimal gland, external auditory canal, etc. However, it seldom involves the infratemporal fossa and extremely few cases are reported in the literature and coexistent contralateral synchronous PA is nowhere reported in literature. The infratemporal fossa tumour posed a diagnostic dilemma and therapeutic challenge because of its concealed location which we dealt successfully with endoscopic sublabial trans maxillary approach.

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An unusual pleomorphic adenoma

RGO - Revista Gaúcha de Odontologia ◽

10.1590/1981-86372014000300000141930 ◽

2014 ◽

Vol 62 (3) ◽

pp. 319-324

Author(s):

Christiano Sampaio QUEIROZ ◽

Roberto Almeida de AZEVEDO ◽

Antonio Irineu TRINDADE NETO ◽

Caetano Guilherme Carvalho PONTES ◽

Rafael de Queiroz MOURA

Keyword(s):

Salivary Gland ◽

Salivary Glands ◽

Pleomorphic Adenoma ◽

Histopathological Examination ◽

Minor Salivary Gland ◽

Surgical Excision ◽

Biological Behavior ◽

Surgical Removal ◽

Minor Salivary Glands ◽

Recommended Treatment

Pleomorphic adenoma is the most common neoplasm in major and minor salivary glands. It constitutes approximately 90% of all benign salivary gland lesions and the parotid is the most affected location. When the minor salivary glands are affected, it mostly occurs at the junction of the hard and soft palates. The diagnosis is complex because of the great histological variety and biological behavior of this tumor, a histopathological examination being essential. The recommended treatment is surgical excision. For lesions located superficially in the parotid gland, superficial parotidectomy - identifying and preserving the facial nerve - is necessary. Lesions in the palate or gums sometimes demand a margin of safety, being excised below the periosteum, including the overlying mucosa. With correct surgical removal, the prognosis is excellent. The aim of this study is to report a case of an unusual minor salivary gland pleomorphic adenoma in the hard palate, describing the most important aspects of this pathology.

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