scholarly journals An unusual pleomorphic adenoma

2014 ◽  
Vol 62 (3) ◽  
pp. 319-324
Author(s):  
Christiano Sampaio QUEIROZ ◽  
Roberto Almeida de AZEVEDO ◽  
Antonio Irineu TRINDADE NETO ◽  
Caetano Guilherme Carvalho PONTES ◽  
Rafael de Queiroz MOURA

Pleomorphic adenoma is the most common neoplasm in major and minor salivary glands. It constitutes approximately 90% of all benign salivary gland lesions and the parotid is the most affected location. When the minor salivary glands are affected, it mostly occurs at the junction of the hard and soft palates. The diagnosis is complex because of the great histological variety and biological behavior of this tumor, a histopathological examination being essential. The recommended treatment is surgical excision. For lesions located superficially in the parotid gland, superficial parotidectomy - identifying and preserving the facial nerve - is necessary. Lesions in the palate or gums sometimes demand a margin of safety, being excised below the periosteum, including the overlying mucosa. With correct surgical removal, the prognosis is excellent. The aim of this study is to report a case of an unusual minor salivary gland pleomorphic adenoma in the hard palate, describing the most important aspects of this pathology.

Author(s):  
Sooraj Somah

Salivary gland tumors are rare tumors in the head and neck region and Pleomorphic Adenoma (PA) is the commonest salivary gland tumor. It is a benign tumor usually affecting parotid, submandibular or minor salivary glands. In minor salivary glands, the palate and lip are the commonest sites. Histopathological examination and various imaging techniques aid n diagnosis. Wide surgical excision is the treatment of choice. Here we present a rare case of PA of the buccal mucosa.


2015 ◽  
Vol 03 (01) ◽  
pp. 047-050
Author(s):  
Gourav Ahuja ◽  
Jaideep Marya ◽  
Poonam Sood

AbstractSalivary gland tumors account for less than 3% of the head and neck tumors. Among various salivary gland tumors, pleomorphic adenoma is most common and accounts for 60- 70% of the benign tumors of salivary glands. However, the involvement of minor salivary glands of buccal mucosa is extremely uncommon and reported to be 4% only. Salivary glands may present with a diverse range of lesions presenting a challenge to even the most experienced clinician. We report two rare cases of pleomorphic adenoma of minor salivary glands of buccal mucosa in a 45 year old female and 70 years old male respectively. It includes clinical features, diagnosis and treatment of the tumor.


2013 ◽  
Vol 3 ◽  
pp. 4 ◽  
Author(s):  
Prathi Venkata Sarath ◽  
N. Kannan ◽  
Rajendra Patil ◽  
Rakesh Kumar Manne ◽  
Beeraka Swapna ◽  
...  

Basal cell adenocarcinoma (BCAC) is a rare neoplasm accounting for only 2.9% of all salivary gland neoplasms. BCAC involving palatal minor salivary glands are exceedingly rare, and only 10 cases have been reported in the literature. The treatment of choice is surgical excision. Here, we report a case of a 55-year-old male patient with massive BCAC of palatal minor salivary gland extending into the maxillary sinus. This is the first case of BCAC treated by radiotherapy followed by chemotherapy. A follow-up check conducted after 14-months showed good prognosis.


2020 ◽  
Vol 9 (5) ◽  
pp. 449-452
Author(s):  
Laís Guimarães Pinto ◽  
Nathalia Farias Dantas de Figueiredo ◽  
Thaynara Cavalcante Moreira Romão ◽  
Lucas André Barros Ferreira ◽  
Murilo Quintão dos Santos ◽  
...  

Introdução: O adenoma pleomórfico (AP) é um tumor de glândulas salivares, misto, benigno composto de células epiteliais e mioepiteliais dispostas em vários padrões morfológicos, demarcadas dos tecidos circundantes por uma cápsula fibrosa. Dentre as glândulas salivares, é predominante nas intraorais com maior frequência no palato. Sua etiopatologia ainda é controversa. Objetivo: Relatar um caso clínico de adenoma pleomórfico localizado em região póstero lateral direito, do palato tratado cirurgicamente. Relato do Caso: Paciente, sexo feminino, 55 anos, foi encaminhada com laudo histopatológico de adenoma pleomórfico. Ao exame físico, foi observou um aumento de volume caracterizado como um nódulo séssil, consistente à palpação, localizado em palato duro direito, com aproximadamente 4cm de extensão em seu maior diâmetro, superfície íntegra, coloração normal e indolor. Ao exame tomográfico, imagem unilocular, bem delimitada, com reabsorção óssea local. Como tratamento, optou-se pela exérese cirúrgica da lesão sob anestesia geral, a qual foi realizada sem intercorrências. Paciente atualmente se encontra com 1 ano de pós-operatório sem sinais de recidiva. Conclusão: O tipo de tratamento descrito apresenta excelente prognóstico, com baixas taxas de recidiva.Descritores: Adenoma Pleomorfo; Cirurgia Bucal; Patologia Bucal.ReferênciasSharma A, Deshmukh S, Shaikh A, Dabholkar J. Pleomorphic adenoma of the minor salivary gland of the cheek. Singapore Med J. 2013;54(9):e183-4. Arumugam P, Christopher PJ, Kumar S, Kengasubbiah S, Shenoy V. Pleomorphic adenoma of the palate: a. case report. Cureus 11(3):e4308.Khan MN, Raza SS, Hussain Zaidi SA, Haq IU, Hussain AK, Nadeem MD, Farid K. Pleomorphic Adenoma Of Minor Salivary Glands. J Ayub Med Coll Abbottabad. 2016;28(3):620-22. Chaturvedi M, Jaidev A, Thaddanee R, Khilnani AK. Large Pleomorphic Adenoma of Hard Palate. Ann Maxillofac Surg. 2018;8(1):124-126.Oliveira LJ, Castro HHO, Leão PLR, Leal RM, Horta MCR, Souza PEA. Tratamento de adenoma pleomórfico em palato: relato de 2 casos e revisão de literatura. Rev Port Estomatol Med Dent Cir Maxilofac. 2016;57(1):55-61.Porto DE, Cavalcante JR, Cavalcante Júnior JR, Costa MCF, Pereira SM. Adenoma Pleomórfico de Parótida – Relato de Caso. Rev cir traumatol buco-maxilo-fac. 2014;14(2):15-18;Melo MNB, Nogueira Neto JN, Souza SR, Dultra FKAA, Dultra JA. Adenoma pleomórfico em lábio superior: Relato de caso. Rev. cir. traumatol. buco-maxilo-fac.2016;16(2):40-3.Erdem MA, Cankaya AB, Güven G, Olgaç V, Kasapoğlu C. Pleomorphic adenoma of the palate. J Craniofac Surg. 2011;22(3):1131-4.Takahashi H, Fujita S, Tsuda N, Tezuka F, Okabe H. Intraoral minor salivary gland tumors: a demographic and histologic study of 200 cases. Tohoku J Exp Med. 1990;161(2):111-28. Loiola RF, Matos FR, Nonaka CFW, Lopes FF, Cruz MCFN. Perfil epidemiológico das neoplasias de glândulas salivares diagnosticadas em São Luís-MA. J Bras Patol Med Lab. 2009;45(5):413-20.Tiago RSL, Castro GA, Ricardo LAC, Bühler RB, Fava AS. Adenoma pleomórfico de parótida: aspectos clínicos, diagnósticos e terapêuticos. Rev Bras Otorrinolaringol. 2003;69(4):485-89.Khan MN, Raza SS, Hussain Zaidi SA, Haq IU, Hussain AK, Nadeem MD, Farid K. Pleomorphic Adenoma Of Minor Salivary Glands. J Ayub Med Coll Abbottabad. 2016;28(3):620-22. Soares AB, Demasi APD, Altemani A, Araújo VC. Increased mucin 1 expression in recurrence and malignant transformation of salivary gland pleomorphic adenoma. Histopathology. 2011; 58(3):377-82.Soares AB, Demasi AP, Tincani AJ, Martins AS, Altemani A, de Araújo VC. The increased PDGF-A, PDGF-B and FGF-2 expression in recurrence of salivary gland pleomorphic adenoma. J Clin Pathol. 2012;65(3):272-77.Maia FPA, Oliveira PRK, Santos JVQM, Costa DFN, Andrade ESS. Abordagem minimamente invasiva para tratamento de adenoma pleomórfico em palato: caso clínico. Rev Cir Traumatol Bucomaxilofac. 2019;19(3):21-4.


1995 ◽  
Vol 109 (5) ◽  
pp. 466-468 ◽  
Author(s):  
Bonnie L. Kemp ◽  
John G. Batsakis ◽  
Adel K. El-Naggar ◽  
Sophia N. Kotliar ◽  
Mario A. Luna

AbstractThe major salivary glands are considered to rarely be the sites of primary terminal duct adenocarcinomas, a neoplasm with a considerable predilection for origin from intraoral minor salivary glands. We present a clinicopathological study of 22 terminal duct adenocarcinomas of the parotid gland, the largest single series to date. A comparison between the parotid neoplasms and over 200 minor salivary gland terminal duct adenocarcinomas indicates there is little difference in biological behaviour and confirms the low-grade quality of the carcinomas, regardless of site of origin.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Saman Vegari ◽  
Masoud Naderpour ◽  
Alireza Hemmati ◽  
Hosein Baybordi

Introduction. Although pleomorphic adenoma is the most common neoplasm of the salivary glands, this tumor most commonly involves the minor salivary glands of palatal and rarely occurs in cervical region.Case Report. A 21-year-old female referred to our clinic due to painless mass of right upper region of neck. After paraclinical and pathologic evaluation, it was diagnosed as cervical pleomorphic adenoma.Conclusion. Pleomorphic adenoma may be rarely involving the neck. Although the prognosis is good, the choice treatment is the complete resection of the tumor.


2020 ◽  
Vol 13 (10) ◽  
pp. e235932
Author(s):  
Sofia Dutra ◽  
Miguel Rito ◽  
Miguel Vilares ◽  
Alexandra Borges

Mucinous cystadenocarcinoma of minor salivary glands is an extremely rare entity that has only recently been described, with a few published cases in the English literature. A 42-year-old woman with a history of a surgically excised mucinous cystadenoma of the oral tongue, presented with a painful swelling in the oral tongue slowly growing for 1 month. On clinical examination, there was a firm, relatively well-circumscribed mass in the left posterior border of the mobile tongue. Subsequent MRI scan revealed a heterogeneous lesion composed of multiple cysts separated by contrast enhancing septa, in the posterior two-thirds of the left tongue. Imaging findings were similar to those of the previously resected mass, suggesting local relapse of the primary lesion. A complete surgical excision was performed and the histopathological examination revealed typical features of a low-grade mucinous cystadenocarcinoma of minor salivary glands.


2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Serdal Celik ◽  
Osman Kilic ◽  
Tulay Zenginkinet ◽  
M. Tayyar Kalcioglu

Salivary gland tumors are rare among all head and neck tumors. Pleomorphic adenoma (PA) is the most commonly seen subtype, and 85% of the cases are located in the parotid gland. PA may very rarely be seen in minor salivary glands. Minor salivary gland PAs are mostly located in the hard and soft palates. Nasopharyngeal PA is very rare, and a total of 8 cases have been published to date. In this case report, a 51-year-old female patient who had nasopharyngeal PA with chondroid metaplasia is presented, and we review the relevant literature.


1996 ◽  
Vol 110 (4) ◽  
pp. 376-378 ◽  
Author(s):  
Lydia Badia ◽  
Justin N. Weir ◽  
Anthony C. Robinson

AbstractPleomorphic adenomas arising from sites other than the major or minor salivary glands are uncommon. We describe a case of pleomorphic adenoma in the subcutaneous tissue of the nasomaxillary crease. An identical tumour was previously excised from the right nasal cavity. The possible aetiology of these heterotopic salivary gland tumours is discussed.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Digvijay Singh Rawat ◽  
Divij Sonkhya ◽  
Nishi Sonkhya ◽  
Shubha Gupta

Parapharyngeal space tumors are rare and constitute only 0.5–1.0% of head and neck tumors. Minor salivary gland tumor is still rare in parapharyngeal space. We are reporting a case of pleomorphic adenoma of minor salivary gland of parapharyngeal space. A 42-year-old female presented with a history of mass in the oropharynx for 3 years. She presented with “hot potato voice” and dysphagia. CECT and MRI were done, showing large parapharyngeal space tumor. FNAC was suspicious for tumor of nerve cell origin. Tumor was excised using “paramedian mandibulotomy with mandibular swing approach”. Histopathological examination was inconclusive, suggesting possibility of extraskeletal myxoid chondrosarcoma, solitary fibrous tumor, neurogenic tumor. On immunohistochemistry, tumor was positive for cytokeratin, EMA (dim), S-100, and P 63 and negative for SMA thus proving the case as myoepithelial cell-rich pleomorphic adenoma.


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