Early prediction of outcome in acute pancreatitis: A retrospective study on single parameters and scores

AbstractNow there is no clinical scale for early prediction of refractory Mycoplasma pneumoniae pneumonia (RMPP). The aim of this study is to identify indicators and develop an early predictive scale for RMPP in hospitalized children. First we conducted a retrospective cohort study of children with M. pneumoniae pneumonia admitted to Children’s Hospital of Nanjing Medical University, China in 2016. Children were divided into two groups, according to whether their pneumonia were refractory and the results were used to develop an early predictive scale. Second we conducted a prospective study to validate the predictive scale for RMPP in children in 2018. 618 children were included in the retrospective study, of which 73 with RMPP. Six prognostic indicators were identified and included in the prognostic assessment scale. The sensitivity of the prognostic assessment scale was 74.0% (54/73), and the specificity was 88.3% (481/545) in the retrospective study. 944 children were included in the prospective cohort, including 92 with RMPP, the sensitivity of the prognostic assessment scale was 78.3% (72/92) and the specificity was 86.2% (734/852). The prognostic assessment scale for RMPP has high diagnostic accuracy and is suitable for use in standard clinical practice.

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The “Two‐Step” approach for classifying the severity of acute pancreatitis: a retrospective study

Journal of Hepato-Biliary-Pancreatic Sciences ◽

10.1002/jhbp.943 ◽

2021 ◽

Author(s):

Yun Zhang ◽

Cheng Zhang ◽

Wen‐Qiao Yu ◽

Zhi‐En Wang ◽

Jian Zhang ◽

...

Keyword(s):

Acute Pancreatitis ◽

Retrospective Study

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Ultrasonographic Monitoring in 38 Dogs with Clinically Suspected Acute Pancreatitis

Veterinary Sciences ◽

10.3390/vetsci7040180 ◽

2020 ◽

Vol 7 (4) ◽

pp. 180

Author(s):

Federico Puccini Leoni ◽

Tina Pelligra ◽

Simonetta Citi ◽

Veronica Marchetti ◽

Eleonora Gori ◽

...

Keyword(s):

Acute Pancreatitis ◽

Retrospective Study ◽

Clinical Examination ◽

Pancreatic Lipase ◽

Abdominal Ultrasound ◽

Diagnostic Evaluation ◽

Ultrasonographic Diagnosis ◽

Study Population

Abdominal ultrasound examinations (AUEs) are commonly used in the diagnostic evaluation of canine acute pancreatitis (AP). The purpose of this retrospective study was to evaluate and monitor the ultrasonographic changes observed in dogs with clinically suspected AP on consecutive AUEs. The study population was constituted by 38 client-owned dogs hospitalized for no less than 48 h from January 2016 to December 2019. Dogs included in this study were suspected of AP based on the clinical examination and abnormal rapid specific canine pancreatic lipase test performed at admission. Dogs were submitted to two AUEs, the first on the first day of hospitalization, and the second between 40–52 h after the first one. Twelve dogs had both AUEs suggestive of AP. Fourteen dogs received an ultrasonographic diagnosis of AP exclusively on the second AUE. Twelve dogs remained negative on both the first and the second AUE. In 26 out of 38 patients the second AUE was suggestive of AP. If a patient is suspected of AP, it is advisable to carry out ultrasonographic monitoring at least within the first 52 h after admission, since ultrasonographic signs of AP may only become observable later after hospitalization.

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