scholarly journals Development of a scale for early prediction of refractory Mycoplasma pneumoniae pneumonia in hospitalized children

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ying Bi ◽  
Yifan Zhu ◽  
Xiao Ma ◽  
Jiejing Xu ◽  
Yun Guo ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Mycoplasma Pneumoniae ◽  
Assessment Scale ◽  
Prognostic Indicators ◽  
Hospitalized Children ◽  
Early Prediction ◽  
Prognostic Assessment ◽  
Standard Clinical Practice ◽  
Children First ◽  
A Prospective Study

AbstractNow there is no clinical scale for early prediction of refractory Mycoplasma pneumoniae pneumonia (RMPP). The aim of this study is to identify indicators and develop an early predictive scale for RMPP in hospitalized children. First we conducted a retrospective cohort study of children with M. pneumoniae pneumonia admitted to Children’s Hospital of Nanjing Medical University, China in 2016. Children were divided into two groups, according to whether their pneumonia were refractory and the results were used to develop an early predictive scale. Second we conducted a prospective study to validate the predictive scale for RMPP in children in 2018. 618 children were included in the retrospective study, of which 73 with RMPP. Six prognostic indicators were identified and included in the prognostic assessment scale. The sensitivity of the prognostic assessment scale was 74.0% (54/73), and the specificity was 88.3% (481/545) in the retrospective study. 944 children were included in the prospective cohort, including 92 with RMPP, the sensitivity of the prognostic assessment scale was 78.3% (72/92) and the specificity was 86.2% (734/852). The prognostic assessment scale for RMPP has high diagnostic accuracy and is suitable for use in standard clinical practice.

Lifespan of peripheral intravenous short catheters in hospitalized children: A prospective study

2021 ◽  
pp. 112972982110052
Author(s):  
Maria Elizabeth Gómez-Neva ◽  
Martin Alonso Rondon Sepulveda ◽  
Adriana Buitrago-Lopez
Keyword(s):  
Cohort Study ◽  
Prospective Study ◽  
The Other ◽  
Hospitalized Children ◽  
Intravenous Catheter ◽  
Survival Analyses ◽  
Median Lifespan ◽  
Pediatric Services ◽  
A Prospective Study ◽  
Intravenous Catheters

Objective: To estimate the recommended lifespan of 223 peripheral intravenous accesses in pediatric services. Method: In this cohort study, we monitored the time of intravenous catheter between insertion and removal in children aged up to 15 years old in a Hospital from Bogotá-Colombia. The routine catheter observations was registered in questionnaires during nursing shifts. Survival analyses were performed to analyze the lifespan of the catheter free of complications. Results: The median lifespan of peripheral intravenous catheters without complications was 129 h (IQR 73.6–393.4 h). This median time free from complications was much lower for children ⩽1 year 98.3 h (IQR 63–141 h), than for participants aged >1 year 207.4 h (IQR 100–393 h). Catheters of 24 G (gauge) caliber had a median complication free time of 128 h (IQR 69–207 h) and 22 G calibers 144 h (IQR 103–393 h). Conclusions: In this study, 75% of peripheral indwell catheters remained free from complications for 74 h, the other extreme 25% of these patients could remain up to 393 h.

scholarly journals Adverse reactions to oxacillin in hospitalized children: a prospective study

2007 ◽  
Vol 7 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Mariana de Oliveira Brizeno de Souza ◽  
Maria da Conceição Castro de Araújo ◽  
Raquel Araújo de Santiago ◽  
Helena Lutéscia Luna Coelho ◽  
Marta Maria de França Fonteles
Keyword(s):  
Exposure Time ◽  
Treatment Duration ◽  
Adverse Reactions ◽  
Therapeutic Interventions ◽  
Hospitalized Children ◽  
Significant Relation ◽  
Moderate Severity ◽  
A Prospective Study ◽  
Established Treatment

OBJECTIVES: follow-up of children exposed to oxacillin during hospitalization focusing on adverse reactions. METHODS: patients were selected from the pediatric wards of two hospitals in Fortaleza (Hospital Universitário Walter Cantídio-HUWC and Hospital Infantil Albert Sabin-HIAS) from the first oxacillin prescription with a prospective cohort study between October, 2000 and July, 2001 (HUWC) and July/2001 and March, 2002 (HIAS). Patients' follow-up was performed by daily visits to the wards and medical charts and prescription analysis. Suspected oxacillininduced adverse reactions (OxAR cases) were notified and classified according to causality and severity. Related statistic tests were completed. RESULTS: of the 130 patients exposed to oxacillin, 27 had OxAR (20.8%). Fever was the most frequent reaction (50%) followed by rash (35.7%). The majority of reactions were considered Probable, for oxacillin was the only medication involved and 92.6% of the cases had Moderate severity with the need of therapeutic interventions caused by OxAR. A significant relation between oxacillin exposure time and OxAR was determined as well as hospitalization time and the appearance of adverse reactions. Exposure time over 14 days to oxacillin was established as a risk factor for OxAR (relative risk = 5.49). CONCLUSIONS: careful administration of oxacillin in children is recommended with established treatment duration. Empiric and prolonged use must be avoided.

scholarly journals Screening of epileptic seizures in children and adolescents with hydrocephalus and ventriculoperitoneal shunt

2009 ◽  
Vol 15 (3) ◽  
pp. 106-109 ◽  
Author(s):  
Raimundo Francisco de Amorim Júnior ◽  
Suerda Emiliana Cavalcanti Dantas ◽  
Rodrigo de Holanda Mendonça ◽  
Abdiel de Lira Rolim ◽  
Maria Luiza de Carvalho Jales ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Data Analysis ◽  
Prospective Study ◽  
Children And Adolescents ◽  
Ventriculoperitoneal Shunt ◽  
Epileptic Seizures ◽  
Significant Difference ◽  
A Prospective Study ◽  
Larger Sample ◽  
Diagnosis Age

OBJECTIVES: To assess the occurrence of epileptic seizures (ES) in children and adolescents with hydrocephalus and their relationship with ventriculoperitoneal shunt (VPS) treatment. METHODS: Retrospective study of 45 patients from both genders, aged 0 to 18 years, with hydrocephalus and presenting with ES or not. The following variables were analyzed: gender, hydrocephalus etiology, age at diagnosis, age at initial VPS treatment, age at first ES and types of ES. RESULTS: Data analysis showed the following: 20 (44.4%) presented with ES, 13 (65%) of the girls and seven (35%) of the boys. There was a predominance of ES in the girls, but with no statistically significant difference. In total, 13 (65%) patients used VPS. Of the 13 patients with VPS and ES, it was observed that the onset of ES was after VPS in 10 (76.9%) individuals, whereas it occurred before VPS in two (15.4%). CONCLUSIONS: The results showed no association between VPS treatment and ES (ρ=0.832); however, most of the patients presented with their first ES episode after VPS, suggesting a possible relationship between this treatment and the occurrence of ES. A larger sample and a prospective study might answer this question.

Serology and Carriage of Pseudomonas pseudomallei: A Prospective Study in 1000 Hospitalized Children in Northeast Thailand

1993 ◽  
Vol 167 (1) ◽  
pp. 230-233 ◽  
Author(s):  
P. Kanaphun ◽  
N. Thirawattanasuk ◽  
Y. Suputtamongkol ◽  
P. Naigowit ◽  
D. A. B. Dance ◽  
...  
Keyword(s):  
Prospective Study ◽  
Hospitalized Children ◽  
Northeast Thailand ◽  
Pseudomonas Pseudomallei ◽  
A Prospective Study

Assessment of Aortic Stenosis Severity Using Pressure Drop Coefficient: A Retrospective Study in Humans

2013 ◽  
Author(s):  
Anup K. Paul ◽  
Mohamed Effat ◽  
Jason J. Paquin ◽  
Rupak K. Banerjee
Keyword(s):  
Retrospective Study ◽  
Pressure Drop ◽  
Aortic Stenosis ◽  
Clinical Decision Making ◽  
Dynamic Pressure ◽  
Clinical Decision ◽  
Diagnostic Parameters ◽  
Stenosis Severity ◽  
Preliminary Study ◽  
A Prospective Study

Accurate assessment of the stenosis severity is critical in patients with aortic stenosis (AS). The ambiguities and reduced sensitivities of the current diagnostic parameters can result in sub-optimal clinical decision making. In this preliminary study, we investigate the functional diagnostic parameter CDP (ratio of the transvalvular pressure drop to the proximal dynamic pressure) for the assessment of AS severity by correlating with the current diagnostic parameters. CDP was calculated using diagnostic parameters obtained from retrospective chart reviews. CDP values were calculated independently from Doppler and catheterization measurements. CDP exhibited better correlation with transvalvular pressure drop and jet velocity simultaneously, than when correlated independently with the same diagnostic parameters. CDP increases with increasing AS severity, which is consistent with hydrodynamic principles. This retrospective study is a prelude to a prospective study to evaluate CDP for AS severity assessment.

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