Anti-pinworm activity of novel coumarin-based trisubstituted methanes in Syphacia obvelata-infected mice

2021 ◽  
pp. 102425
Author(s):  
Errini Decruse Dhar ◽  
Arun K. Yadav ◽  
Grace Basumatary ◽  
Ghanashyam Bez
Keyword(s):  
Syphacia Obvelata

Effective eradication of pinworms (Syphacia obvelata and Aspiculuris tetraptera) with Polygonum cognatum Meissn

2019 ◽  
Vol 196 ◽  
pp. 63-67 ◽  
Author(s):  
Fatma Tuğçe Gürağaç Dereli ◽  
Mert Ilhan ◽  
Esma Kozan ◽  
Esra Küpeli Akkol
Keyword(s):  
Syphacia Obvelata ◽  
Aspiculuris Tetraptera

scholarly journals Sanitary profile in mice and rat colonies in laboratory animal houses in Minas Gerais: I - Endo and ectoparasites

2007 ◽  
Vol 59 (6) ◽  
pp. 1478-1484 ◽  
Author(s):  
K.A. Bicalho ◽  
F.T.M. Araújo ◽  
R.S. Rocha ◽  
O.S. Carvalho
Keyword(s):  
Physical Environment ◽  
Minas Gerais ◽  
Public Institutions ◽  
Hymenolepis Nana ◽  
Syphacia Muris ◽  
Syphacia Obvelata ◽  
Animal House ◽  
Aspiculuris Tetraptera ◽  
Giardia Muris ◽  
Sanitary Conditions

The sanitary conditions of 13 animal houses in nine public institutions in Minas Gerais, and the presence of endo and ectoparasites of mice and rats colonies kept in these facilities were evaluated. Data about barriers to prevent the transmission of diseases and a program of sanitary monitoring were obtained through a questionnaire and local visit. Parasitological methods were performed for diagnosing mite, lice, helminthes, and protozoa parasites in 344 mice and 111 rats. Data have shown that the majority of the animal houses had neither proper physical environment nor protection barriers to prevent the transmission of infections. Parasitological results have shown that only one animal house (7.7%) had parasite free animals, whereas the others have presented infected animals and the prevalences of parasites in the mice colonies were: Myobia musculi (23.1%); Myocoptes musculinus (38.5%); Radfordia affinis (15.4%); Syphacia obvelata (92.3%); Aspiculuris tetraptera (23.1%); Hymenolepis nana (15.4%); Spironucleus muris (46.2%); Giardia muris (46.2%); Tritrichomonas muris (53.8%); Trichomonas minuta (61.5%); Hexamastix muris (7.7%); and Entamoeba muris (84.6%). As for the rat colonies, the prevalences were: Poliplax spinulosa (8.1%); Syphacia muris (46.2%); Trichosomoides crassicauda (28.6%); Spironucleus muris (85.7%); Tritrichomonas muris (85.7%); Trichomonas minuta (85.7%); Hexamastix muris (14.3%) and Entamoeba muris (85.7%).

scholarly journals New host record of some gastrointestinal parasites of Irrawaddy squirrel (Callosciurus pygerythrus) from Chittagong, Bangladesh

2018 ◽  
Vol 46 (2) ◽  
pp. 87-103
Author(s):  
Md Afzal Hussain ◽  
Rajib Acharjee ◽  
Benazir Ahmed
Keyword(s):  
Host Specificity ◽  
Parasite Species ◽  
Host Record ◽  
Gastrointestinal Parasites ◽  
Hymenolepis Diminuta ◽  
University Campus ◽  
Gi Tract ◽  
New Host ◽  
New Host Record ◽  
Syphacia Obvelata

Gastrointestinal (GI) tract of 60 Irrawaddy squirrels (Callosciurus pygerythrus) were collected between September 2013 and August 2014 from four different spots of Chittagong University campus and its adjacent areas to study the ento-helminth fauna. Eight different parasite species were identified - one belonging to Cestoda and represented by Hymenolepis diminuta, and the remaining seven were to Nematoda viz., Strongyloides callosciurus, Trichuris ovis, Monodontus sp., Cyclodontostomum purvisi, Moguranema nipponicum, Ascarops talpa and Syphacia obvelata. The nematodes were found as dominant species most preferably inhabiting the small intestine. The present host is the new host record for all of these parasites and S. callosciurus, T. ovis, Monodontus sp., M. nipponicum and A. talpa are the new records for Bangladesh too. All these parasites have very wide host specificity, though most of them are restricted to various rodent hosts but H. diminuta and S. callosciurus were found to have more wider specificity, including other vertebrates too. All identified parasites might have been acquired from the environment where the host inhabits, since host specificity perspective no parasites were found to be specific to the present host. H. diminuta and Syphacia obvelata might have zoonotic role to other wild animals and human and vice versa. Bangladesh J. Zool. 46(2): 87-103, 2018

Studies on the function of the oxyurid egg-shell

Parasitology ◽  
1980 ◽  
Vol 81 (1) ◽  
pp. 103-113 ◽  
Author(s):  
D. A. Wharton
Keyword(s):  
Embryonic Development ◽  
Water Loss ◽  
Complex Structure ◽  
Permeability Barrier ◽  
Lipid Layer ◽  
Insect Eggs ◽  
Egg Shells ◽  
Syphacia Obvelata ◽  
Egg Shell ◽  
Aspiculuris Tetraptera

SUMMARYThe egg-shell of Hammerschmidtiella diesingi and Aspiculuris tetraptera reduces the rate of water loss from the egg when exposed to desiccation. Staining of the enclosed larva by acid fuchsin and the collapse of eggs exposed to desiccation indicate that the permeability barrier is heat labile. This suggests that the lipid layer is the main permeability barrie of the shell. The complex structure of the uterine layers has a similar morphology to the respiratory structures of the chorion of some insect eggs. Reflections from the shell, the rate of embryonic development under various conditions and the penetration of lead ions indicate that the shell does not trap a layer of air when immersed in water and the uterine layers cannot, therefore, function as a plastron network. Calculations indicate that if diffusion is limited to the pores in the external uterine layer, the area available for gaseous exchange is reduced by 85·5% in H. diesingi, 95·6% in A. tetraptera and 96·8% in Syphacia obvelata. It is suggested that the uterine layers of oxyurid egg-shells function in a similar fashion to the pores in bird egg-shells and the aeropyles in the chorion of insect egg-shells which do not possess plastron networks. These structures reduce water loss from the egg whilst ensuring an adequate supply of oxygen for embryonic development.

scholarly journals Immunomodulatory effect of Syphacia obvelata in treatment of experimental DSS-induced colitis in mouse model

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Niloofar Taghipour ◽  
Nariman Mosaffa ◽  
Hamid Asadzadeh Aghdaei ◽  
Mohammad Rostami-Nejad ◽  
Joel V. Weinstock ◽  
...  
Keyword(s):  
Therapeutic Group ◽  
Weight Changes ◽  
Mesenteric Lymph Nodes ◽  
Body Weight Changes ◽  
Dss Colitis ◽  
Mesenteric Lymph ◽  
Tnf Α ◽  
Parasite Infections ◽  
Ifn Γ ◽  
Syphacia Obvelata

AbstractThe ability of helminth parasite infections to manipulate the immune system of their host towards T regulatory responses has been proposed to suppress the inflammatory response. The aim of this study was to investigate the protective and therapeutic effect of Syphacia obvelata in the treatment of experimental DSS -induced colitis. 50 male C57BL/6 mice were divided into 5 groups: healthy uninfected controls, DSS colitis, receiving only S. obv, preventive (S. obv + DSS) and therapeutic group (DSS + S.obv). Colitis intensity was investigated by measuring body weight changes, stool consistency/bleeding and colon length. To evaluate the immune responses induced by this nematode, TNF-α, IL-10, IL-17, IFN-γ and expressing of FoxP3+ T cells were measured in mesenteric lymph nodes and Peyer’s patches cells. Mice in preventive and therapeutic groups treated with S. obv egg significantly ameliorated the severity of the DSS colitis, indicated by the reduced disease manifestations, improved histopathological scores correlated with the up regulation of Treg responses and down regulation of proinflammatory cytokines. S. obv can prevention and reverse on-going murine DSS colitis. The data suggest that induction of Tregs and change in cytokine profiles during helminthic therapies were responsible for reversed inflammatory events in IBD.

Eradication of the pinworm Syphacia obvelata from an animal unit by anthelmintic therapy

1979 ◽  
Vol 13 (2) ◽  
pp. 115-118 ◽  
Author(s):  
Dawn Owen ◽  
Jon A. Turton
Keyword(s):  
Drinking Water ◽  
Syphacia Obvelata

Summary Thiabendazole incorporated in the diet at a rate of 0·1%, fed to all animals over a period of 3 months, successfully eliminated the parasite from the colony. Samples taken 12 months after treatment were still negative for the parasite. During the period between the discovery of the organism and the preparation of the diet a course of piperazine citrate was administered at a rate of 2 g/litre in the drinking water in order to limit the spread of the infection.

Continuous feed medication with thiabendazole for the removal of Hymenolepis nana, Syphacia obvelata and Aspiculuris tetraptera in naturally infected mice

1975 ◽  
Vol 49 (3) ◽  
pp. 173-177 ◽  
Author(s):  
L. F. Taffs
Keyword(s):  
High Activity ◽  
Inbred Strain ◽  
Treatment Period ◽  
Day Treatment ◽  
Post Mortem ◽  
Hymenolepis Nana ◽  
Single Drug ◽  
Continuous Feed ◽  
Syphacia Obvelata ◽  
Aspiculuris Tetraptera

AbstractA medicated diet containing 0.3% thiabendazole fed continuously to 26 mice for 7 days removed 9 out of 11 (82%) Hymenolepis nana, (one tapeworm remaining in each of two mice), 17 out of 17 (100%) Syphacia obvelata and 8 out of 8 (100%) Aspiculuris tetraptera infections. By contrast in 26 non-treated mice 9 out of 10 Hymenolepis, 17 out of 18 Syphacia and 8 out of 8 Aspiculuris infections persisted through the 7 day treatment period, and at post mortem examination 38 Hymenolepsis, 1,562 Syphacia and 4,911 Aspiculuris worms were recovered. In a second experiment 100% removal of 23 Hymenolepis and 20 Syphacia infections was obtained after 14 days medication of 38 mice. High activity against both roundyvorms and tapeworms of mice was thus obtained using one single drug. Some unexplained deaths amongst inbred strain C3H/Hef Nimr mice occurred within seven day's of the continuous medication.

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