Sensitivity and specificity of Addenbrooke’s Cognitive Examination, Mattis Dementia Rating Scale, Frontal Assessment Battery and Mini Mental State Examination for diagnosing dementia in Parkinson’s disease

2012 ◽  
Vol 18 (5) ◽  
pp. 553-556 ◽  
Author(s):  
B. Kaszás ◽  
N. Kovács ◽  
I. Balás ◽  
J. Kállai ◽  
Z. Aschermann ◽  
...  
2002 ◽  
Vol 17 (7) ◽  
pp. 685-686 ◽  
Author(s):  
W. Freidl ◽  
W.-J. Stronegger ◽  
A. Berghold ◽  
B. Reinhart ◽  
K. Petrovic ◽  
...  

1999 ◽  
Vol 5 (4) ◽  
pp. 301-307 ◽  
Author(s):  
URSULA HOHL ◽  
MICHAEL GRUNDMAN ◽  
DAVID P. SALMON ◽  
RONALD G. THOMAS ◽  
LEON J. THAL

Little information exists regarding the performance of Spanish-speaking versus English-speaking patients with Alzheimer's disease (AD) on the Mini-Mental State Examination and the Mattis Dementia Rating Scale. In an attempt to identify culturally biased MMSE items or DRS subscales, we matched Spanish-speaking Hispanic and English-speaking non-Hispanic White community-dwelling AD patients by their MMSE scores and examined specific items within each scale. Our findings indicate that Hispanic AD patients perform significantly worse than non-Hispanics in terms of total DRS score, scores on the DRS subscales for Conceptualization and Memory, and on serial subtraction (or backward spelling item) of the MMSE. While mildly to moderately demented Hispanic and non-Hispanic patients obtained comparable scores on the DRS, severely impaired Spanish-speaking participants obtained considerably lower DRS scores than their English-speaking counterparts. The discrepancy in the DRS scores of the severely impaired Hispanic and non-Hispanic examinees might reflect a cultural bias in the test or educational differences between the groups. Alternatively, the DRS may be more sensitive than the MMSE for detecting severe cognitive impairment in Hispanic patients. (JINS, 1999, 5, 301–307.)


2009 ◽  
Vol 5 (4S_Part_10) ◽  
pp. P292-P292 ◽  
Author(s):  
Hee Jin Kang ◽  
Young-Hee Chang ◽  
Ha-Ry Na ◽  
Min Jae Baek ◽  
Hyun Jung Kim ◽  
...  

2021 ◽  
Author(s):  
Hideyuki Hoshi ◽  
Yoshihito Shigihara

Abstract Cognitive impairment and dementia are conventionally categorised according to their causative disease, such as Alzheimer's disease and cerebrovascular disease. Cognitive impairments of different aetiologies often share pathological cerebral blood circulation patterns, characterised by perfusion and resistance. Here, we show that these two features are associated with distinct types of cognitive impairment. Using carotid ultrasonography, we evaluated the circulation status of individuals with little to no subjective cognitive symptoms. We assessed individuals’ cognitive status using the Frontal Assessment Battery for executive function and Mini-Mental State Examination for learning and memory. Regression analysis showed that the hyper-resistance and hypo-perfusion components predicted the Frontal Assessment Battery and Mini Mental State Examination scores, respectively. These results are consistent with previous findings of hyper-resistance being associated with atherosclerosis, which disproportionately affects the frontal lobe and contributes to executive function impairments; meanwhile, hypo-perfusion disproportionately affects temporal lobe functions associated with learning and memory. We propose a novel concept that cognitive impairments fall into two subtypes regardless of the brain disease: hyper-resistance and hypo-perfusion subtypes. As these subtypes can be measured noninvasively and are treatable, this distinction would help design preventive and therapeutic strategies for dementia.


Sign in / Sign up

Export Citation Format

Share Document