Salvianolic Acid A Relieves Cognitive Disorder after Chronic Cerebral Ischemia: Involvement of Drd2/Cryab/NF-κB Pathway

2021 ◽  
pp. 105989
Author(s):  
Yujiao Yang ◽  
Junke Song ◽  
NanNan Liu ◽  
Guangyi Wei ◽  
Shan Liu ◽  
...  
Phytomedicine ◽  
2017 ◽  
Vol 25 ◽  
pp. 8-14 ◽  
Author(s):  
Qaisar Mahmood ◽  
Guang-Fa Wang ◽  
Gang Wu ◽  
Huan Wang ◽  
Chang-Xin Zhou ◽  
...  

2017 ◽  
Vol 0 (1.87) ◽  
pp. 117-122
Author(s):  
O.L. Tovazhnianska ◽  
I.O. Lapshina ◽  
A.H. Chernenko ◽  
O.I. Kauk

2018 ◽  
Vol 13 (10) ◽  
pp. 1934578X1801301
Author(s):  
Nguyen Huu Tung ◽  
Le Quoc Hung ◽  
Ha Van Oanh ◽  
Duong Thi Ly Huong ◽  
Phuong Thien Thuong ◽  
...  

Danshen ( Salvia miltiorrhiza Bunge) is one of the most used medicinal plants in the Oriental medicine and has been well studied for application in modern medicine. In our continuing study on chemical constituents of danshen cultivated in Vietnam, using chromatography separation resulted in the isolation of six phenolic compounds including a benzophenone, iriflophenone 2- O- α-L-rhamnopyranoside (1), and five phenolic acids including rosmarinic acid (2), rosmarinic acid methyl ester (3), rosmarinic acid ethyl ester (4), salvianolic acid A methyl ester (5) and salvianolic acid A ethyl ester (6) from the butanol portion of the danshen crude extract. Beside the typically main phenolic acid components, to our knowledge, iriflophenone 2- O- α-L-rhamnopyranoside (1) was first isolated from salvia sp. On biological testing, compound 1 showed strong antiproliferative activity on HL-60 leukemia cells with the IC50 of 8.9 μM; compounds 1 and 3–6 inhibited markedly nitric oxide production in lipopolysaccharide-treated RAW 264.7 cells.


Planta Medica ◽  
1990 ◽  
Vol 56 (04) ◽  
pp. 360-363 ◽  
Author(s):  
Shigeru Murakami ◽  
Haruko Kijima ◽  
Yoshihiko Isobe ◽  
Makoto Muramatsu ◽  
Hironaka Aihara ◽  
...  

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