scholarly journals Comparative study of two immunoassays used for the determination of serum vitamin D

2021 ◽  
pp. e00242
Author(s):  
Raquel Lahoz ◽  
Juan Pelegrín Sánchez ◽  
Silvia Górriz ◽  
Pilar Calmarza
2019 ◽  
Vol 26 (11) ◽  
pp. 1810-1814
Author(s):  
Sabiha Iqbal ◽  
Syed Imran Ali Shah ◽  
Mirza Zeeshan Sikandar

Obesity is a common clinical disorder featuring excessive buildup of body fat. The bioavailability of vitamin D in obese subjects is lowered because of its sequestration in the superfluous fat tissue. Hypovitaminosis D itself is associated with glucose intolerance, insulin resistance, dyslipidemia and hypertension, which are also linked to obesity. Objectives: To compare and correlate serum vitamin D and insulin resistance in controls and overweight / obese males. Study Design: Cross Sectional, Comparative Study. Setting: The study was conducted in the Department of Physiology, Post – Graduate Medical Institute (PGMI) in collaboration with Lahore General Hospital and Central Park Medical College. Period: From 7th June 2018 to 10th Oct 2018. Material and Methods: Eighty male subjects (age range 35-50 years) included in this cross-sectional comparative study were divided into two groups on the basis of BMI; Group I: non-obese (control) BMI < 25 Kg/m2 (n=40) and Group II: overweight / obese males with BMI ˃25 Kg/m2 (n=40). Fasting serum vitamin D (25 hydroxy cholecalciferol; 25-OH D, serum insulin and blood glucose levels were measured. Insulin resistance (IR) was estimated from fasting serum glucose levels taken in mmol/l and the fasting serum insulin taken in µIU/ml by using Homeostasis Model Assessment-estimated Insulin Resistance (HOMA-IR index). Results: Group II had lower serum 25-OH vitamin D levels and higher HOMA-IR index than control group. Significant negative correlation was present between serum vitamin D and HOMA-IR. Conclusion: Vitamin D deficiency may promote insulin resistance in overweight or obese individuals.


2018 ◽  
Vol 50 (11) ◽  
pp. 1975-1980 ◽  
Author(s):  
Alaa Mohamed Abd El aal ◽  
Sameh Fayek GamalEl Din ◽  
Laila Ahmed Rashed ◽  
Abd El Rahman Bakry Tawfik ◽  
Mohammed Said ElSheemy

2014 ◽  
Vol 20 (5) ◽  
pp. A91-A91
Author(s):  
John Finnell ◽  
Ryan Bradley ◽  
Nataliya Bulayeva ◽  
Kevin Rosenblatt

1980 ◽  
Vol 13 (9) ◽  
pp. 1029-1034 ◽  
Author(s):  
Roger Bouillon ◽  
Hugo Van Baelen ◽  
Pieter De Moor

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