scholarly journals Cross-sectional associations between accelerometry-measured physical activity, left atrial size, and indices of left ventricular diastolic dysfunction: The Tromsø Study

2021 ◽  
Vol 21 ◽  
pp. 101290
Author(s):  
Kim Arne Heitmann ◽  
Maja-Lisa Løchen ◽  
Laila A. Hopstock ◽  
Michael Stylidis ◽  
Boye Welde ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diastolic Dysfunction ◽  
Left Atrial ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Left Atrial Size ◽  
Cross Sectional ◽  
Atrial Size ◽  
Ventricular Diastolic Dysfunction

scholarly journals The Grade of Left Ventricular Diastolic Dysfunction as a Predictive Factor for Permanent Atrial Fibrillation

2015 ◽  
Vol 61 (3) ◽  
pp. 158-160
Author(s):  
Cerghizan Anda ◽  
Keresztesi Arthur Atilla ◽  
Bataga Simona ◽  
Tilea Ioan
Keyword(s):  
Atrial Fibrillation ◽  
Diastolic Dysfunction ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Left Atrial Size ◽  
Ventricular Ejection Fraction ◽  
Permanent Atrial Fibrillation ◽  
Atrial Size ◽  
Ventricular Diastolic Dysfunction

Abstract The objective of this study was to find a link between the grade of left ventricular diastolic dysfunction (LVDD) and the progression to permanent non-valvular atrial fibrillation (AF), in a group of patients with left ventricular diastolic dysfunction and paroxysmal or persistent atrial fibrillation. Methods: A bidirectional study on 57 patients meeting the inclusion criteria was conducted; each patient was admitted in a university-based hospital between January 1st - June, 30, 2013, with a follow up 3 and 6 months later. Permanent atrial fibrillation development was followed. Results: Out of the 57 patients, 23 had paroxysmal AF and 34 were with persistent AF. After six months, 21 patients progressed to permanent AF, representing 36.84% of the total patients. Female patients with age over 65 had more often atrial fibrillation, but more men progressed to a sustained form of AF. No statistically significant difference regarding the grade of diastolic dysfunction, the left atrial size or volume, or the left ventricular ejection fraction was observed between the patients with progression, compared to those without progression. Conclusions: The grade of left ventricular diastolic dysfunction did not prove to be a predictive factor for permanent atrial fibrillation, neither the left atrial size or volume, or the left ventricular ejection fraction.

scholarly journals Left Atrial Volume, Cardiorespiratory Fitness, and Diastolic Function in Healthy Individuals: The HUNT Study, Norway

2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Jon Magne Letnes ◽  
Bjarne Nes ◽  
Kristina Vaardal‐Lunde ◽  
Martine Bratt Slette ◽  
Harald Edvard Mølmen‐Hansen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diastolic Dysfunction ◽  
Cardiorespiratory Fitness ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Atrial Volume ◽  
Ventricular Diastolic Dysfunction ◽  
Age And Sex

Background Left atrial ( LA ) size and cardiorespiratory fitness ( CRF ) are predictors of future cardiovascular events in high‐risk populations. LA dilatation is a diagnostic criterion for left ventricular diastolic dysfunction. However, LA is dilated in endurance athletes with high CRF , but little is known about the association between CRF and LA size in healthy, free‐living individuals. We hypothesized that in a healthy population, LA size was associated with CRF and leisure‐time physical activity, but not with echocardiographic indexes of left ventricular diastolic dysfunction. Methods and Results In this cross‐sectional study from HUNT (Nord‐Trøndelag Health Study), 107 men and 138 women, aged 20 to 82 years, without hypertension, cardiovascular, pulmonary, or malignant disease participated. LA volume was assessed by echocardiography and indexed to body surface area LAVI (left atrial volume index). CRF was measured as peak oxygen uptake ( VO 2peak ) using ergospirometry, and percent of age‐ and‐sex‐predicted VO 2peak was calculated. Indexes of left ventricular diastolic dysfunction were assessed in accordance with latest recommendations. LAVI was >34 mL/m 2 in 39% of participants, and LAVI was positively associated with VO 2peak and percentage of age‐ and‐sex‐predicted VO 2peak (β (95% CI) 0.18 (0.09‐0.28) and 0.10 (0.05‐0.15)), respectively) weighted minutes of physical activity per week (β [95% CI ], 0.01 [0.003–0.015]). LAVI was not associated with other indexes of left ventricular diastolic dysfunction. There was an effect modification between age and VO 2peak /percentage of age‐ and‐sex‐predicted VO 2peak showing higher LAVI with advanced age and higher VO 2peak /percentage of age‐ and‐sex‐predicted VO 2peak as presented in prediction diagrams. Conclusions Interpretation of LAVI as a marker of diastolic dysfunction should be done in relation to age‐relative CRF . Studies on the prognostic value of LAVI in fit subpopulations are needed.

scholarly journals Characteristics of Cirrhosis Patients With Left Ventricular Diastolic Dysfunction In China: A Single-Center Retrospective Study.

2021 ◽  
Author(s):  
Jingjing Hu ◽  
Zhaobin Cai
Keyword(s):  
Diastolic Dysfunction ◽  
Demographic Data ◽  
Laboratory Data ◽  
Alcoholic Cirrhosis ◽  
Left Ventricular Diastolic Function ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Cross Sectional ◽  
Ventricular Diastolic Dysfunction ◽  
Inner Diameter

Abstract Objective: Mounting evidence links cirrhosis patients with left ventricular diastolic dysfunction（LVDD） has a poor prognosis. However, little is known about these particular individuals. Therefore, we conducted this cross-sectional study to assess the prevalence of LVDD and its associated risk factors.Methods: Consecutive cirrhosis patient who were attending Hangzhou Xixi hospital from January 2018 to December 2019 were included in this study. According to the American Society of Echocardiography 2016 criteria, cirrhosis patients were sorted into two group: the left ventricular diastolic dysfunction(LVDD) group and left ventricular diastolic function normal(LVDDn) group. Patients’ demographic data, clinical characteristics, laboratory data were recorded. Furthermore, we conducted a multi-factor analysis.Results: A total of 398cirrhosis patients were included in the study. The incidence of LVDD in this study was 49.7% (198 cases). In this study, the mean age and BMI of the patients were 52.9±8.2 years and 23.0±3.3kg/m2，respectively. Of 398 patients, 255(64.1%) of them were males. With regard to etiology, there were 296 patients (74.4%) with hepatitis B cirrhosis and 59 patients (14.8%) with alcoholic cirrhosis. The LVDD group had higher age, higher BMI, greater frequency of ascites and esophageal varices, prolonged prothrombin time, increased international normalized ratio, increased bilirubin, increased CK and AST, and longer QT interval than the LVDDn group(p<0.05, both). In terms of echocardiography, the LVDD group had larger aortic inner diameter, left atrial inner diameter and left ventricular wall diastolic thickness than LVDDn group(p<0.05, both). The multivariate analysis showed age>55 years, BMI>24kg/m2, hepatic decompensated, QTcB>440ms were independently associated with risk of LVDD.Conclusion: The prevalence of LVDD among cirrhosis patients was 49.8%. Cirrhosis patients with LVDD had worse liver function. Further, age>55 years, BMI>24kg/m2, hepatic decompensated, QTcB>440ms were independent predictors of LVDD.

Left Ventricular Vortex Ring Dynamics and Their Association to Early Diastolic Filling

2011 ◽  
Author(s):  
Kelley C. Stewart ◽  
John J. Charonko ◽  
Takahiro Ohara ◽  
William C. Little ◽  
Pavlos P. Vlachos
Keyword(s):  
Diastolic Dysfunction ◽  
Left Atrial ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Diastolic Filling ◽  
Compensatory Mechanisms ◽  
Ring Dynamics ◽  
Ventricular Diastolic Dysfunction ◽  
Ventricular Filling ◽  
Early Filling

Diastolic dysfunction is the impairment of the filling in the left ventricle. Patients with left ventricular diastolic dysfunction (LVDD) lose the ability to adjust left ventricular filling properties without increasing left atrial pressure [1]. Although LVDD is very prevalent, it currently remains difficult to diagnose due to inherent atrioventricular compensatory mechanisms including increased heart rate, increased left ventricular (LV) contractility, and increased left atrial (LA) pressure. Although variations within the early diastolic filling velocity have been previously observed [2], the physical mechanism for the deceleration of the early filling wave is not understood.

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