scholarly journals In- vitro and in -vivo degradation studies of freeze gelated porous chitosan composite scaffolds for tissue engineering applications

2017 ◽  
Vol 136 ◽  
pp. 31-38 ◽  
Author(s):  
Saad B. Qasim ◽  
Shehriar Husain ◽  
Ying Huang ◽  
Maksym Pogorielov ◽  
Volodymyr Deineka ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Composite Scaffolds ◽  
Engineering Applications ◽  
Porous Chitosan ◽  
Degradation Studies ◽  
Chitosan Composite ◽  
In Vivo Degradation

Bioprinted Nanoparticles for Tissue Engineering Applications

2009 ◽  
Author(s):  
Kivilcim Buyukhatipoglu ◽  
Robert Chang ◽  
Wei Sun ◽  
Alisa Morss Clyne
Keyword(s):  
Tissue Engineering ◽  
Tissue Growth ◽  
Bioactive Components ◽  
Engineering Applications ◽  
Tissue Properties ◽  
Native Tissue ◽  
3D Architecture

Tissue engineering may require precise patterning of cells and bioactive components to recreate the complex, 3D architecture of native tissue. However, it is difficult to image and track cells and bioactive factors once they are incorporated into the tissue engineered construct. These bioactive factors and cells may also need to be moved during tissue growth in vitro or after implantation in vivo to achieve the desired tissue properties, or they may need to be removed entirely prior to implantation for biosafety concerns.

Porous-conductive chitosan scaffolds for tissue engineering II. in vitro and in vivo degradation

2005 ◽  
Vol 16 (11) ◽  
pp. 1017-1028 ◽  
Author(s):  
Ying Wan ◽  
Aixi Yu ◽  
Hua Wu ◽  
Zhaoxu Wang ◽  
Dijiang Wen
Keyword(s):  
Tissue Engineering ◽  
Chitosan Scaffolds ◽  
In Vivo Degradation

The effect of silk gland sericin protein incorporation into electrospun polycaprolactone nanofibers on in vitro and in vivo characteristics

2015 ◽  
Vol 3 (5) ◽  
pp. 859-870 ◽  
Author(s):  
Linhao Li ◽  
Yuna Qian ◽  
Chongwen Lin ◽  
Haibin Li ◽  
Chao Jiang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Silk Gland ◽  
Engineering Applications ◽  
Nanofibrous Scaffolds ◽  
Protein Incorporation

Silk middle gland extracted sericin protein based electrospun nanofibrous scaffolds with excellent biocompatibility have been developed for tissue engineering applications.

Preparation, Characterization and In Vitro Release Kinetics of Vancomycin Carried β-TCP/Chitosan Composite Microspheres Used as Bone Tissue Engineering Scaffolds

2012 ◽  
Vol 512-515 ◽  
pp. 1821-1825
Author(s):  
Lin Zhang ◽  
Xue Min Cui ◽  
Qing Feng Zan ◽  
Li Min Dong ◽  
Chen Wang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Release Kinetics ◽  
In Vitro Release ◽  
Cross Linking ◽  
Tissue Engineering Scaffolds ◽  
Composite Microspheres ◽  
Chitosan Composite ◽  
Vitro Release

A novel microsphere scaffolds composed of chitosan and β-TCP containing vancomycin was designed and prepared. The β-TCP/chitosan composite microspheres were prepared by solid-in-water-in-oil (s/w/o) emulsion cross-linking method with or without pre-cross-linking process. The mode of vancomycin maintaining in the β-TCP/chitosan composite microspheres was detected by Fourier transform infrared spectroscopy (FTIR). The in vitro release curve of vancomycin in simulated body fluid (SBF) was estimated. The results revealed that the pre-cross-linking prepared microspheres possessed higher loading efficiency (LE) and encapsulation efficiency (EE) especially decreasing the previous burst mass of vancomycin in incipient release. These composite microspheres got excellent sphere and well surface roughness in morphology. Vancomycin was encapsulated in composite microspheres through absorption and cross-linking. While in-vitro release curves illustrated that vancomycin release depond on diffusing firstly and then on the degradation ratio later. The microspheres loading with vancomycin would be to restore bone defect, meanwhile to inhibit bacterium proliferation. These bioactive, degradable composite microspheres have potential applications in 3D tissue engineering of bone and other tissues in vitro and in vivo.

Gamma-Poly(glutamic acid)/Chitosan Composite Scaffolds for Tissue Engineering Applications

2007 ◽  
pp. 567-572
Author(s):  
Sung Pei Tsai ◽  
Chien Yang Hsieh ◽  
Chung Yu Hsieh ◽  
Yaw Nan Chang ◽  
Da Ming Wang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Glutamic Acid ◽  
Composite Scaffolds ◽  
Engineering Applications ◽  
Chitosan Composite

scholarly journals Gellan Gum Injectable Hydrogels for Cartilage Tissue Engineering Applications: In Vitro Studies and Preliminary In Vivo Evaluation

2010 ◽  
Vol 16 (1) ◽  
pp. 343-353 ◽  
Author(s):  
João T. Oliveira ◽  
Tírcia C. Santos ◽  
Luís Martins ◽  
Ricardo Picciochi ◽  
Alexandra P. Marques ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cartilage Tissue Engineering ◽  
Gellan Gum ◽  
In Vitro Studies ◽  
Cartilage Tissue ◽  
Engineering Applications ◽  
In Vivo Evaluation ◽  
Injectable Hydrogels

Novel HA-PVA/NOCC bilayered scaffold for osteochondral tissue-engineering applications – Fabrication, characterization, in vitro and in vivo biocompatibility study

2013 ◽  
Vol 113 ◽  
pp. 25-29 ◽  
Author(s):  
Nurul Syuhada Ibrahim ◽  
Genasan Krishnamurithy ◽  
Hanumantha Rao Balaji Raghavendran ◽  
Subramaniam Puvaneswary ◽  
Ng Wuey Min ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Engineering Applications ◽  
Osteochondral Tissue ◽  
Osteochondral Tissue Engineering ◽  
Biocompatibility Study

A review on 3D printing in tissue engineering applications

2022 ◽  
Vol 0 (0) ◽  
Author(s):  
Mohan Prasath Mani ◽  
Madeeha Sadia ◽  
Saravana Kumar Jaganathan ◽  
Ahmad Zahran Khudzari ◽  
Eko Supriyanto ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
3D Printing ◽  
Cell Adherence ◽  
Engineering Applications ◽  
Proliferation And Differentiation ◽  
3D Printed ◽  
Printing Techniques

Abstract In tissue engineering, 3D printing is an important tool that uses biocompatible materials, cells, and supporting components to fabricate complex 3D printed constructs. This review focuses on the cytocompatibility characteristics of 3D printed constructs, made from different synthetic and natural materials. From the overview of this article, inkjet and extrusion-based 3D printing are widely used methods for fabricating 3D printed scaffolds for tissue engineering. This review highlights that scaffold prepared by both inkjet and extrusion-based 3D printing techniques showed significant impact on cell adherence, proliferation, and differentiation as evidenced by in vitro and in vivo studies. 3D printed constructs with growth factors (FGF-2, TGF-β1, or FGF-2/TGF-β1) enhance extracellular matrix (ECM), collagen I content, and high glycosaminoglycan (GAG) content for cell growth and bone formation. Similarly, the utilization of 3D printing in other tissue engineering applications cannot be belittled. In conclusion, it would be interesting to combine different 3D printing techniques to fabricate future 3D printed constructs for several tissue engineering applications.

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