Rapid Prototyping Airway and Vascular Models from 3D Rotational Angiography: Beans to Cup 3D Printing

Objectives To date, the ultimate decision to treat iliac artery stenoses in patients suffering from symptomatic peripheral arterial disease is based on the patient’s symptoms and on visual inspection of angiographical images. The primary aim of this study was to investigate the accuracy of geometry-based methods (i.e. visual inspection and quantitative vascular analysis (Viewforum version R7.2v1 Advanced vessel analysis, Philips Healthcare, Best, The Netherlands) of 3D rotational angiography) to identify the severity of equivocal iliac artery stenosis in peripheral arterial disease patients with intra-arterial hyperemic pressure measurements (gold standard) as a reference. Methods Twenty patients with symptomatic iliac artery stenoses were subjected to 3D rotational angiography. Intra-arterial pressure measurements under hyperemic conditions were performed across 24 visually identified iliac artery stenoses. Three experienced interventional-radiologists retrospectively estimated the lumen diameter reduction by visual inspection. Furthermore, quantitative vascular analysis was performed on the 3D rotational angiography data. Geometry-based estimates were classified into two groups: lumen diameter reduction of <50% (non-significant) and diameter reduction [Formula: see text]50% (significant), and compared to the intra-arterial hyperemic pressure gradients. A stenosis causing a pressure gradient (Δp) ≥10 mmHg was considered hemodynamically significant. Results Visual inspection and quantitative vascular analysis correctly identified hemodynamically significant stenoses in, respectively, 83% and 67% of the 24 iliac artery stenoses. Quantitative vascular analysis-based identification of hemodynamic significant stenoses (Δp ≥ 10 mmHg) could be optimized by lowering the threshold to a 42% lumen diameter reduction which improved the accuracy from 67% to 83%. Conclusions Visual inspection of 3D rotational angiography by experienced interventional-radiologists has an 83% accuracy to identify hemodynamic significant iliac artery stenoses (Δ p ≥10 mmHg). The use of quantitative vascular analysis software did not improve accuracy.

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3D MODELLING AND RAPID PROTOTYPING FOR CARDIOVASCULAR SURGICAL PLANNING – TWO CASE STUDIES

ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences ◽

10.5194/isprsarchives-xli-b5-887-2016 ◽

2016 ◽

Vol XLI-B5 ◽

pp. 887-893 ◽

Cited By ~ 6

Author(s):

E. Nocerino ◽

F. Remondino ◽

F. Uccheddu ◽

M. Gallo ◽

G. Gerosa

Keyword(s):

3D Printing ◽

Rapid Prototyping ◽

Case Studies ◽

Surgical Planning ◽

Heart Diseases ◽

Coronary Vessels ◽

3D Modelling ◽

Patient Specific ◽

Surface Model ◽

Medical Imagery

In the last years, cardiovascular diagnosis, surgical planning and intervention have taken advantages from 3D modelling and rapid prototyping techniques. The starting data for the whole process is represented by medical imagery, in particular, but not exclusively, computed tomography (CT) or multi-slice CT (MCT) and magnetic resonance imaging (MRI). On the medical imagery, regions of interest, i.e. heart chambers, valves, aorta, coronary vessels, etc., are segmented and converted into 3D models, which can be finally converted in physical replicas through 3D printing procedure. In this work, an overview on modern approaches for automatic and semiautomatic segmentation of medical imagery for 3D surface model generation is provided. The issue of accuracy check of surface models is also addressed, together with the critical aspects of converting digital models into physical replicas through 3D printing techniques. A patient-specific 3D modelling and printing procedure (Figure 1), for surgical planning in case of complex heart diseases was developed. The procedure was applied to two case studies, for which MCT scans of the chest are available. In the article, a detailed description on the implemented patient-specific modelling procedure is provided, along with a general discussion on the potentiality and future developments of personalized 3D modelling and printing for surgical planning and surgeons practice.

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Low-Dose 3D Rotational Angiography in Measuring the Size of Intracranial Aneurysm: In Vitro Feasibility Study Using Aneurysm Phantom

Neurointervention ◽

10.5469/neuroint.2020.00437 ◽

2021 ◽

Vol 16 (1) ◽

pp. 59-63

Author(s):

Hee Jong Ki ◽

Bum-soo Kim ◽

Jun-Ki Kim ◽

Jai Ho Choi ◽

Yong Sam Shin ◽

...

Keyword(s):

Intracranial Aneurysm ◽

Endovascular Treatment ◽

Low Dose ◽

Three Dimensional ◽

3D Measurement ◽

Rotational Angiography ◽

3D Rotational Angiography ◽

Conventional Dose ◽

Noninferiority Margin

Purpose: Three-dimensional (3D) measurement of intracranial aneurysms is important in planning endovascular treatment, and 3D rotational angiography (RA) is effective in accurate measurement. The purpose of this study was to evaluate the feasibility of low dose 3D RA (5 seconds 0.10 μGy/frame) in measuring an intracranial aneurysm using an in vitro phantom.Materials and Methods: We investigated an <I>in vitro</i> 3D phantom of an intracranial aneurysm with 10 acquisitions of 3D RA with a conventional dose (5 seconds 0.36 μGy/frame) and 10 acquisitions with a low-dose (5 seconds 0.10 μGy/frame). 3D size and neck diameters of the aneurysm were measured and compared between the 2 groups (conventional and low-dose) using noninferiority statistics.Results: The aneurysm measurements were well-correlated between the 2 readers, and noninferiority in the measurement of aneurysmal size of low-dose 3D RA was demonstrated, as the upper margin of the 1-sided 97.5% confidence interval did not cross the pre-defined noninferiority margin of 0.2 mm by the 2 readers.Conclusion: Low-dose (5 seconds 0.10 μGy/frame) cerebral 3D RA is technically feasible and not inferior in in vitro 3D measurement of an intracranial aneurysm. Thus, low-dose 3D RA is promising and needs further evaluation for its clinical utility in the planning of endovascular treatment of an intracranial aneurysm.

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Experimental studies of the quality of embossed characters of the Braille alphabet

Bulletin of the Polish Academy of Sciences Technical Sciences ◽

10.1515/bpasts-2016-0068 ◽

2016 ◽

Vol 64 (3) ◽

pp. 607-614

Author(s):

R. Barczyk ◽

D. Jasińska-Choromańska

Keyword(s):

Surface Roughness ◽

Statistical Analysis ◽

3D Printing ◽

Rapid Prototyping ◽

Experimental Studies ◽

Printed Text ◽

Blind Persons ◽

Blind Individuals

Abstract The paper presents studies pertaining to the quality of embossed characters of the Braille alphabet used, among other applications, for tagging drug labels. The following parameters of embossed inscriptions were measured: height, diameter of the dots and surface roughness (18 samples with various combinations of their values). 48 blind individuals assessed the quality of the printed text. Statistical analysis proved that a text with dots having height of 0.9 millimeter, diameter of 1.6 millimeters and roughness Ra of about 1 micrometer to be the best. The samples had been made using two different methods of rapid prototyping: PolyJet and SLS. 3D printing is increasingly popular and the studies proved the usefulness of these methods for labeling with embossed inscriptions, due to the repeatability, durability and quality they ensure. The assessing group of blind individuals was comprised of 24 persons 14–17 years old and other 24 persons aged over 60 who were not proficient in reading Braille alphabet, This allows to conclude that a text featuring the above values of the parameters will be easy to read for the majority of blind persons.

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Use of the stereoscopic virtual reality display system for the detection and characterization of intracranial aneurysms: A Icomparison with conventional computed tomography workstation and 3D rotational angiography

Clinical Neurology and Neurosurgery ◽

10.1016/j.clineuro.2018.04.034 ◽

2018 ◽

Vol 170 ◽

pp. 93-98 ◽

Cited By ~ 3

Author(s):

Xiujuan Liu ◽

Haiquan Tao ◽

Xigang Xiao ◽

Binbin Guo ◽

Shangcai Xu ◽

...

Keyword(s):

Computed Tomography ◽

Virtual Reality ◽

Intracranial Aneurysms ◽

Display System ◽

Rotational Angiography ◽

3D Rotational Angiography

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Novel antimicrobial materials designed for the 3D printing of medical devices used during the COVID-19 crisis

Rapid Prototyping Journal ◽

10.1108/rpj-09-2020-0219 ◽

2021 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Samuel Furka ◽

Daniel Furka ◽

Nitin Chandra Teja Chandra Teja Dadi ◽

Patrik Palacka ◽

Dominika Hromníková ◽

...

Keyword(s):

3D Printing ◽

Rapid Prototyping ◽

Medical Devices ◽

Hybrid Material ◽

Weight Ratio ◽

Layered Silicate ◽

Content Type ◽

Antimicrobial Materials ◽

The Stability ◽

Designed Materials

Purpose This study aims to describe the preparation of antimicrobial material usable in 3D printing of medical devices. Despite the wealth of technological progress at the time of the crisis caused by SARS-CoV-2 virus: Virus that causes current Pandemic situation (COVID-19), the global population had long been exposed beforehand to an acute absence of essential medical devices. As a response, a new type of composite materials intended for rapid prototyping, based on layered silicate saponite (Sap), antimicrobial dye phloxine B (PhB) and thermoplastics, has been recently developed. Design/methodology/approach Sap was modified with a cationic surfactant and subsequently functionalized with PhB. The hybrid material in powder form was then grounded with polyethylene terephthalate-glycol (PETG) or polylactic acid (PLA) in a precisely defined weight ratio and extruded into printing filaments. The stability and level of cytotoxicity of these materials in various physiological environments simulating the human body have been studied. The applicability of these materials in bacteria and a yeast-infected environment was evaluated. Findings Ideal content of the hybrid material, with respect to thermoplastic, was 15 weight %. Optimal printing temperature and speed, with respect to maintaining antimicrobial activity of the prepared materials, were T = 215°C at 50 mm/s for PETG/SapPhB and T = 230°C at 40 mm/s for PLA/SapPhB. 3 D-printed air filters made of these materials could keep inner air flow at 63.5% and 76.8% of the original value for the PLA/SapPhB and PETG/SapPhB, respectively, whereas the same components made without PhB had a 100% reduction of airflow. Practical implications The designed materials can be used for rapid prototyping of medical devices. Originality/value The new materials have been immediately used in the construction of an emergency lung ventilator, Q-vent, which has been used in different countries during the COVID-19 crisis.

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Novel phantom for performance evaluation of contrast-enhanced 3D rotational angiography

Physica Medica ◽

10.1016/j.ejmp.2021.09.002 ◽

2021 ◽

Vol 90 ◽

pp. 91-98

Author(s):

L.E. Lubis ◽

R.A. Basith ◽

I. Hariyati ◽

D. Ryangga ◽

T. Mart ◽

...

Keyword(s):

Performance Evaluation ◽

Rotational Angiography ◽

3D Rotational Angiography ◽

Contrast Enhanced

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Novel 3D-Printed MEMS Magnetometer with Optical Detection

Proceedings ◽

10.3390/proceedings2130783 ◽

2018 ◽

Vol 2 (13) ◽

pp. 783 ◽

Cited By ~ 1

Author(s):

Matthias Kahr ◽

Wilfried Hortschitz ◽

Harald Steiner ◽

Michael Stifter ◽

Andreas Kainz ◽

...

Keyword(s):

3D Printing ◽

Product Development ◽

Rapid Prototyping ◽

Low Cost ◽

High Accuracy ◽

Structural Performance ◽

Sensitivity Measurement ◽

Optical Readout ◽

3D Printed ◽

Working Principle

This paper reports a novel 3D printed MEMS magnetometer with optical readout, which demonstrates the advantages of 3D printing technology in terms of rapid prototyping. Low-cost and fast product development cycles favour 3D printing as an effective tool. Sensitivity measurement with such devices indicate high accuracy and good structural performance, considering material and technological uncertainties. This paper is focusing on the novelty of the rapid, 3D-printing prototyping approach and verification of the working principle for printed MEMS magnetometers.

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