scholarly journals 3D MODELLING AND RAPID PROTOTYPING FOR CARDIOVASCULAR SURGICAL PLANNING – TWO CASE STUDIES

2016 ◽  
Vol XLI-B5 ◽  
pp. 887-893 ◽  
Author(s):  
E. Nocerino ◽  
F. Remondino ◽  
F. Uccheddu ◽  
M. Gallo ◽  
G. Gerosa
Keyword(s):  
3D Printing ◽  
Rapid Prototyping ◽  
Case Studies ◽  
Surgical Planning ◽  
Heart Diseases ◽  
Coronary Vessels ◽  
3D Modelling ◽  
Patient Specific ◽  
Surface Model ◽  
Medical Imagery

In the last years, cardiovascular diagnosis, surgical planning and intervention have taken advantages from 3D modelling and rapid prototyping techniques. The starting data for the whole process is represented by medical imagery, in particular, but not exclusively, computed tomography (CT) or multi-slice CT (MCT) and magnetic resonance imaging (MRI). On the medical imagery, regions of interest, i.e. heart chambers, valves, aorta, coronary vessels, etc., are segmented and converted into 3D models, which can be finally converted in physical replicas through 3D printing procedure. In this work, an overview on modern approaches for automatic and semiautomatic segmentation of medical imagery for 3D surface model generation is provided. The issue of accuracy check of surface models is also addressed, together with the critical aspects of converting digital models into physical replicas through 3D printing techniques. A patient-specific 3D modelling and printing procedure (Figure 1), for surgical planning in case of complex heart diseases was developed. The procedure was applied to two case studies, for which MCT scans of the chest are available. In the article, a detailed description on the implemented patient-specific modelling procedure is provided, along with a general discussion on the potentiality and future developments of personalized 3D modelling and printing for surgical planning and surgeons practice.

scholarly journals 3D MODELLING AND RAPID PROTOTYPING FOR CARDIOVASCULAR SURGICAL PLANNING – TWO CASE STUDIES

2016 ◽  
Vol XLI-B5 ◽  
pp. 887-893 ◽  
Author(s):  
E. Nocerino ◽  
F. Remondino ◽  
F. Uccheddu ◽  
M. Gallo ◽  
G. Gerosa
Keyword(s):  
3D Printing ◽  
Rapid Prototyping ◽  
Case Studies ◽  
Surgical Planning ◽  
Heart Diseases ◽  
Coronary Vessels ◽  
3D Modelling ◽  
Patient Specific ◽  
Surface Model ◽  
Medical Imagery

In the last years, cardiovascular diagnosis, surgical planning and intervention have taken advantages from 3D modelling and rapid prototyping techniques. The starting data for the whole process is represented by medical imagery, in particular, but not exclusively, computed tomography (CT) or multi-slice CT (MCT) and magnetic resonance imaging (MRI). On the medical imagery, regions of interest, i.e. heart chambers, valves, aorta, coronary vessels, etc., are segmented and converted into 3D models, which can be finally converted in physical replicas through 3D printing procedure. In this work, an overview on modern approaches for automatic and semiautomatic segmentation of medical imagery for 3D surface model generation is provided. The issue of accuracy check of surface models is also addressed, together with the critical aspects of converting digital models into physical replicas through 3D printing techniques. A patient-specific 3D modelling and printing procedure (Figure 1), for surgical planning in case of complex heart diseases was developed. The procedure was applied to two case studies, for which MCT scans of the chest are available. In the article, a detailed description on the implemented patient-specific modelling procedure is provided, along with a general discussion on the potentiality and future developments of personalized 3D modelling and printing for surgical planning and surgeons practice.

scholarly journals Current Practice in Preoperative Virtual and Physical Simulation in Neurosurgery

2020 ◽  
Vol 7 (1) ◽  
pp. 7 ◽  
Author(s):  
Elisa Mussi ◽  
Federico Mussa ◽  
Chiara Santarelli ◽  
Mirko Scagnet ◽  
Francesca Uccheddu ◽  
...  
Keyword(s):  
Clinical Practice ◽  
3D Printing ◽  
Surgical Planning ◽  
Physical Simulation ◽  
Planning Process ◽  
Preoperative Planning ◽  
Cost Effective ◽  
Patient Specific ◽  
Anatomical Models ◽  
Standard Clinical Practice

In brain tumor surgery, an appropriate and careful surgical planning process is crucial for surgeons and can determine the success or failure of the surgery. A deep comprehension of spatial relationships between tumor borders and surrounding healthy tissues enables accurate surgical planning that leads to the identification of the optimal and patient-specific surgical strategy. A physical replica of the region of interest is a valuable aid for preoperative planning and simulation, allowing the physician to directly handle the patient’s anatomy and easily study the volumes involved in the surgery. In the literature, different anatomical models, produced with 3D technologies, are reported and several methodologies were proposed. Many of them share the idea that the employment of 3D printing technologies to produce anatomical models can be introduced into standard clinical practice since 3D printing is now considered to be a mature technology. Therefore, the main aim of the paper is to take into account the literature best practices and to describe the current workflow and methodology used to standardize the pre-operative virtual and physical simulation in neurosurgery. The main aim is also to introduce these practices and standards to neurosurgeons and clinical engineers interested in learning and implementing cost-effective in-house preoperative surgical planning processes. To assess the validity of the proposed scheme, four clinical cases of preoperative planning of brain cancer surgery are reported and discussed. Our preliminary results showed that the proposed methodology can be applied effectively in the neurosurgical clinical practice both in terms of affordability and in terms of simulation realism and efficacy.

scholarly journals Photogrammetry and 3D prototyping: A low-cost resource for training in veterinary orthopedics

2019 ◽  
Vol 49 (12) ◽  
Author(s):  
Luiz Felipe Souza de Lima ◽  
Anna Júlia Brandão Paes de Barros ◽  
Andresa de Cássia Martini ◽  
Matias Bassinello Stocco ◽  
Antonio Henrique Kuczmarski ◽  
...  
Keyword(s):  
Veterinary Medicine ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Surgical Planning ◽  
Low Cost ◽  
Fracture Reduction ◽  
Innovative Technology ◽  
Virtual Model ◽  
Experimental Animals ◽  
Biological Contamination

ABSTRACT: Rapid prototyping (RP) is an innovative technology that allows one to obtain a prototype of a mold quickly and accurately from a virtual model. This study aimed to establish the use of photogrammetry and 3D prototyping for the production of bone biomodels of the canine species for training in orthopedic techniques in veterinary medicine. Virtual bio-modelling was performed by the photogrammetry technique with commercial anatomical pieces, and physical biomodelling was performed by 3D printing. Osteotomies were performed on the biomodels that served as platforms for osteosynthesis of the femur and ileum, and the final product was not associated with a risk of biological contamination, was able to support special orthopedic materials, and was used for training and surgical planning. We concluded that the use of photogrammetry and RP for the production of bone biomodels of the canine species enabled techniques for fracture reduction to be performed with the use of special instruments, enabling training in the area of veterinary orthopedics in an economically viable manner with an alternative to experimental animals.

3D Bioprinted Cardiac Tissues and Devices for Tissue Maturation

2021 ◽  
pp. 1-14
Author(s):  
Veronika Sedlakova ◽  
Christopher McTiernan ◽  
David Cortes ◽  
Erik J. Suuronen ◽  
Emilio I. Alarcon
Keyword(s):  
3D Printing ◽  
Tissue Repair ◽  
Surgical Planning ◽  
Cardiac Tissue ◽  
Treatment Options ◽  
Cardiac Regeneration ◽  
Patient Specific ◽  
Cardiac Tissues ◽  
Cardiovascular Tissue ◽  
Custom Made

Cardiovascular diseases are the leading cause of mortality worldwide. Given the limited endogenous regenerative capabilities of cardiac tissue, patient-specific anatomy, challenges in treatment options, and shortage of donor tissues for transplantation, there is an urgent need for novel approaches in cardiac tissue repair. 3D bioprinting is a technology based on additive manufacturing which allows for the design of precisely controlled and spatially organized structures, which could possibly lead to solutions in cardiac tissue repair. In this review, we describe the basic morphological and physiological specifics of the heart and cardiac tissues and introduce the readers to the fundamental principles underlying 3D printing technology and some of the materials/approaches which have been used to date for cardiac repair. By summarizing recent progress in 3D printing of cardiac tissue and valves with respect to the key features of cardiovascular tissue (such as contractility, conductivity, and vascularization), we highlight how 3D printing can facilitate surgical planning and provide custom-fit implants and properties that match those from the native heart. Finally, we also discuss the suitability of this technology in the design and fabrication of custom-made devices intended for the maturation of the cardiac tissue, a process that has been shown to increase the viability of implants. Altogether this review shows that 3D printing and bioprinting are versatile and highly modulative technologies with wide applications in cardiac regeneration and beyond.

scholarly journals 3D printed patient-specific bone models for anatomy education from medical imaging

2021 ◽  
Author(s):  
Arivazhagan Pugalendhi ◽  
◽  
SenthilMurugan Arumugam ◽  
Rajesh Ranganathan ◽  
Sivakumar Ganesan ◽  
...  
Keyword(s):  
3D Printing ◽  
Surgical Planning ◽  
Thin Layers ◽  
Physical Models ◽  
Patient Specific ◽  
Anatomy Education ◽  
Healthcare Applications ◽  
Surgical Guides ◽  
Solid Objects ◽  
3D Printed

Evolution of 3D printing from medical image datasets are escalating and has widespread in healthcare applications such as anatomical models, surgical guides, and customized implants. In 3D printing, solid objects are fabricated by the frequently added the thin layers of material as per the digital model. This paper demonstrates the fabrication of 3D printed patient-specific bone models of leg and ankle foot from Digital Imaging and Communications in Medicine (DICOM) files. Processing of DICOM file is prepared by D2P (DICOM to PRINT) software and physical models are produced by Stratasys uPrint 3D printer. This 3D printed anatomical model eliminates the requirement of actual human bones, significance of preservation and mistakes in assembly of bones. The results of the study not only encourage education, surgical planning and validating medical devices but stimulate exciting innovations.

scholarly journals The utility of 3D printing for surgical planning and patient-specific implant design for complex spinal pathologies: case report

2017 ◽  
Vol 26 (4) ◽  
pp. 513-518 ◽  
Author(s):  
Ralph J. Mobbs ◽  
Marc Coughlan ◽  
Robert Thompson ◽  
Chester E. Sutterlin ◽  
Kevin Phan
Keyword(s):  
3D Printing ◽  
Spinal Surgery ◽  
Surgical Planning ◽  
Tumor Resection ◽  
Implant Design ◽  
Patient Specific ◽  
Anterior Fusion ◽  
Potential Applications ◽  
3D Printed ◽  
Fusion Cage

OBJECTIVE There has been a recent renewed interest in the use and potential applications of 3D printing in the assistance of surgical planning and the development of personalized prostheses. There have been few reports on the use of 3D printing for implants designed to be used in complex spinal surgery. METHODS The authors report 2 cases in which 3D printing was used for surgical planning as a preoperative mold, and for a custom-designed titanium prosthesis: one patient with a C-1/C-2 chordoma who underwent tumor resection and vertebral reconstruction, and another patient with a custom-designed titanium anterior fusion cage for an unusual congenital spinal deformity. RESULTS In both presented cases, the custom-designed and custom-built implants were easily slotted into position, which facilitated the surgery and shortened the procedure time, avoiding further complex reconstruction such as harvesting rib or fibular grafts and fashioning these grafts intraoperatively to fit the defect. Radiological follow-up for both cases demonstrated successful fusion at 9 and 12 months, respectively. CONCLUSIONS These cases demonstrate the feasibility of the use of 3D modeling and printing to develop personalized prostheses and can ease the difficulty of complex spinal surgery. Possible future directions of research include the combination of 3D-printed implants and biologics, as well as the development of bioceramic composites and custom implants for load-bearing purposes.

scholarly journals 4360 Black Bone MRI from the Lab to Clinical Practice: Eliminating Radiation Exposure in Reconstructive Surgery Patients

2020 ◽  
Vol 4 (s1) ◽  
pp. 105-106
Author(s):  
Marissa Suchyta ◽  
Christopher Hunt ◽  
Waleed Gibreel ◽  
Diya Sabbagh ◽  
Kryzysztof Gorny ◽  
...  
Keyword(s):  
3D Printing ◽  
Radiation Exposure ◽  
Reconstructive Surgery ◽  
Surgical Planning ◽  
Clinical Care ◽  
Ct Scans ◽  
Patient Specific ◽  
Average Deviation ◽  
Virtual Planning ◽  
Virtual Surgical Planning

OBJECTIVES/GOALS: Virtual surgical planning and 3D printing enable streamlined surgeries and increased complexity. These technologies, however, require CT scans and radiation exposure. This project’s goal is to optimize and demonstrate the accuracy of Black Bone MRI for surgical planning in reconstructive surgery. METHODS/STUDY POPULATION: Four common craniofacial surgeries were planned and performed on cadaver specimens (maxillary advancement, orbital floor reconstruction with patient-specific implants, cranial vault reconstruction, and fibular free flap reconstruction of the mandible). For each surgical procedure, ten cadaver heads were used. Five of each surgery were planned and 3D printed guides were created utilizing Black Bone MRI versus five with CT scans. Following mock surgeries, all specimens underwent a post-operative CT scan. 3d reconstruction was performed and surgical accuracy compared to the plan was assessed using GeoMagic Wrap, assessing average post-operative deviation from plan. RESULTS/ANTICIPATED RESULTS: In all surgeries, guides created from Black Bone MRI demonstrated high accuracy to surgical plan. Average osteotomy (cut) deviation from plan was not statistically significantly different when Black Bone MRI was used compared to CT scans for planning and guide creation in the wide variety of craniofacial surgeries performed. The average deviation of post-operative anatomy from pre-operative plan was also not statistically significant when Black Bone MRI versus CT scans were utilized in the surgeries. These results then enabled the translational application of this technology clinically, and we demonstrate a clinical reconstructive craniofacial case planned utilizing Black Bone MRI. DISCUSSION/SIGNIFICANCE OF IMPACT: This study demonstrates that virtual surgical planning and 3d surgical guide creation can be performed using Black Bone MRI with comparable accuracy to CT scans in a wide variety of craniofacial procedures. This could dramatically reduce radiation exposure for patients. The successful segmentation, virtual planning, and 3d printing of accurate guides from Black Bone MRI demonstrate potential to change the pre-operative planning standard of care. This project, overall, also demonstrates the development of new solutions to advance clinical care, thus serving as an example of moving translational science from a concept to the operating room.

Three-dimensional patient-specific cardiac model for surgical planning in Nikaidoh procedure

2014 ◽  
Vol 25 (4) ◽  
pp. 698-704 ◽  
Author(s):  
Israel Valverde ◽  
Gorka Gomez ◽  
Antonio Gonzalez ◽  
Cristina Suarez-Mejias ◽  
Alejandro Adsuar ◽  
...  
Keyword(s):  
Ventricular Septal Defect ◽  
Rapid Prototyping ◽  
Surgical Planning ◽  
Septal Defect ◽  
Three Dimensional ◽  
Magnetic Resonance Images ◽  
Patient Specific ◽  
Complex Congenital Heart Disease ◽  
Cardiac Model ◽  
Cardiovascular Models

AbstractPurpose: To explore the use of three-dimensional patient-specific cardiovascular models using rapid prototyping techniques (fused deposition modelling) to improve surgical planning in patients with complex congenital heart disease. Description: Rapid prototyping techniques are used to print accurate three-dimensional replicas of patients' cardiovascular anatomy based on magnetic resonance images using computer-aided design systems. Models are printed using a translucent polylactic acid polymer. Evaluation: As a proof of concept, a model of the heart of a 1.5-year-old boy with transposition of the great arteries, ventricular septal defect and pulmonary stenosis was constructed to help planning the surgical correction. The cardiac model allowed the surgeon to evaluate the location and dimensions of the ventricular septal defect as well as its relationship with the aorta and pulmonary artery. Conclusions: Cardiovascular models constructed by rapid prototyping techniques are extremely helpful for planning corrective surgery in patients with complex congenital malformations. Therefore they may potentially reduce operative time and morbi-mortality.

Design and 3D printing customized guides for orthopaedic surgery – lessons learned

2018 ◽  
Vol 24 (5) ◽  
pp. 901-913 ◽  
Author(s):  
Diana Popescu ◽  
Dan Laptoiu ◽  
Rodica Marinescu ◽  
Iozefina Botezatu
Keyword(s):  
3D Printing ◽  
Case Studies ◽  
Orthopaedic Surgery ◽  
Development Process ◽  
Lessons Learned ◽  
Patient Specific ◽  
Fused Deposition Modelling ◽  
Content Type ◽  
Fused Deposition ◽  
Surgical Guides

Purpose This paper aims to fill a research gap by presenting design and 3D printing guidelines and considerations which apply to the development process of patient-specific osteotomy guides for orthopaedic surgery. Design/methodology/approach Analysis of specific constraints related to patient-specific surgical guides design and 3D printing, lessons learned during the development process of osteotomy guides for orthopaedic surgery, literature review of recent studies in the field and data gathered from questioning a group of surgeons for capturing their preferences in terms of surgical guides design corresponding to precise functionality (materializing cutting trajectories, ensuring unique positioning and stable fixation during surgery), were all used to extract design recommendations. Findings General design rules for patient-specific osteotomy guides were inferred from examining each step of the design process applied in several case studies in relation to how these guides should be designed to fulfill medical and manufacturing (fused deposition modelling process) constraints. Literature was also investigated for finding other information than the simple reference that the surgical guide is modelled as negative of the bone. It was noticed that literature is focussed more on presenting and discussing medical issues and on assessing surgical outcomes, but hardly at all on guides’ design and design for additive manufacturing aspects. Moreover, surgeons’ opinion was investigated to collect data on different design aspects, as well as interest and willingness to use such 3D-printed surgical guides in training and surgery. Practical implications The study contains useful rules and recommendations for engineers involved in designing and 3D printing patient-specific osteotomy guides. Originality/value A synergetic approach to identify general rules and recommendations for the patient-specific surgical guides design is presented. Specific constraints are identified and analysed using three case studies of wrist, femur and foot osteotomies. Recent literature is reviewed and surgeons’ opinion is investigated.

scholarly journals 3D Printing—A Cutting Edge Technology for Treating Post-Infarction Patients

Life ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 910
Author(s):  
Daniel Cernica ◽  
Imre Benedek ◽  
Stefania Polexa ◽  
Cosmin Tolescu ◽  
Theodora Benedek
Keyword(s):  
3D Printing ◽  
Heart Diseases ◽  
Scientific Evidence ◽  
Interventional Cardiology ◽  
3D Models ◽  
Clinical Applications ◽  
Patient Specific ◽  
Interventional Treatment ◽  
Printing Technology ◽  
Surgery Patient

The increasing complexity of cardiovascular interventions requires advanced peri-procedural imaging and tailored treatment. Three-dimensional printing technology represents one of the most significant advances in the field of cardiac imaging, interventional cardiology or cardiovascular surgery. Patient-specific models may provide substantial information on intervention planning in complex cardiovascular diseases, and volumetric medical imaging from CT or MRI can be translated into patient-specific 3D models using advanced post-processing applications. 3D printing and additive manufacturing have a great variety of clinical applications targeting anatomy, implants and devices, assisting optimal interventional treatment and post-interventional evaluation. Although the 3D printing technology still lacks scientific evidence, its benefits have been shown in structural heart diseases as well as for treatment of complex arrhythmias and corrective surgery interventions. Recent development has enabled transformation of conventional 3D printing into complex 3D functional living tissues contributing to regenerative medicine through engineered bionic materials such hydrogels, cell suspensions or matrix components. This review aims to present the most recent clinical applications of 3D printing in cardiovascular medicine, highlighting also the potential for future development of this revolutionary technology in the medical field.

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