127 Hypertension at an early stage of prenatal is a major risk factor for adverse neonatal outcomes

2016 ◽  
Vol 6 (3) ◽  
pp. 242-243
Author(s):  
Júlio Augusto Gurgel Alves ◽  
Nilce Ariane Spencer Santos ◽  
Francisco Edson de Lucena Feitosa
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Svetlana Popova ◽  
Danijela Dozet ◽  
Graham O’Hanlon ◽  
Valerie Temple ◽  
Jürgen Rehm

Abstract Background The current study aimed to estimate the prevalence of alcohol use identified as a risk factor during pregnancies by the antenatal care providers, resulting in live births in British Columbia (BC) and to examine associations between alcohol use, adverse neonatal outcomes, and pregnancy complications. Methods This population-based cross-sectional study utilized linked obstetrical and neonatal records within the BC Perinatal Data Registry (BCPDR), for deliveries that were discharged between January 1, 2015 and March 31, 2018. The main outcome measures were alcohol use identified as a risk factor during pregnancy, associated maternal characteristics, pregnancy complications, and adverse neonatal outcomes. Estimates for the period and fiscal year prevalence were calculated. Chi-square tests were used to compare adverse neonatal outcomes and pregnancy complications by alcohol use during pregnancy identified as a risk factor. Logistic regression was used to examine the association between alcohol use identified as a risk factor during pregnancy and adverse neonatal outcomes and pregnancy complications, after adjusting for identified risk factors. Results A total of 144,779 linked records within the BCPDR were examined. The period prevalence of alcohol use during pregnancy identified as a risk factor was estimated to be 1.1% and yearly prevalence was 1.1, 1.1, 1.3 and 0.9% from the 2014/2015 to 2017/2018 fiscal years, respectively. Alcohol use identified as a risk factor was associated with younger maternal age, fewer antenatal visits, being primiparous, a history of mental illness, substance use and smoking. Neonates with alcohol use during pregnancy identified as a risk factor had greater odds of being diagnosed with: “low birth weight (1000-2499g)” (ICD-10: P07.1; aOR = 1.25; 95% CI: 1.01, 1.53), “other respiration distress of newborn” (ICD-10: P22.8; aOR = 2.57; 95% CI: 1.52, 4.07), “neonatal difficulty in breastfeeding” (ICD-10: P92.5; aOR = 1.97; 95% CI: 1.27, 2.92) and “feeding problems, unspecified” (ICD-10: P92.9; aOR = 2.06; 95% CI: 1.31, 3.09). Conclusions The prevalence of alcohol use during pregnancy identified as a risk factor was comparable to previous estimates within the BCPDR. Identified prenatal alcohol exposure was associated with notable differences in maternal and neonatal characteristics and adverse neonatal outcomes. More consistent, thorough screening and prevention efforts targeting alcohol use in pregnancy are urgently needed in Canada.


2018 ◽  
Vol 218 (1) ◽  
pp. S355
Author(s):  
Mina Jeong ◽  
Seung Mi Lee ◽  
Sohee Oh ◽  
Subeen Hong ◽  
Jeong Won Oh ◽  
...  

2019 ◽  
Vol 13 (1) ◽  
pp. 46-48
Author(s):  
Miguel Alejandro Rodriguez-Ramos

Diabetes is a major risk factor for heart disease. Diabetic cardiomyopathy is a long-lasting process that affects the myocardium in patients who have no other cardiac conditions. The condition has a complex physiopathology which can be subdivided into processes that cause diastolic and/or systolic dysfunction. It is believed to be more common than reported, but this has not been confirmed by a large study. Diagnosis can involve imaging; biomarkers cannot be used to identify diabetic cardiomyopathy at an early stage. In people with diabetes, there should be a focus on prevention and, if diabetic cardiomyopathy develops, the objective is to delay disease progression. Further studies into identifying and managing diabetic cardiomyopathy are essential to reduce the risk of heart failure in people with diabetes.


2020 ◽  
Author(s):  
Svetlana Popova ◽  
Danijela Dozet ◽  
Graham O'Hanlon ◽  
Valerie Temple ◽  
Jurgen Rehm

Abstract BackgroundThe current study aimed to estimate the prevalence of alcohol use identified as a risk factor during pregnancies by the antenatal care providers, resulting in live births in British Columbia (BC) and to examine associations between alcohol use, adverse neonatal outcomes, and pregnancy complications.MethodsThis population-based cross-sectional study utilized linked obstetrical and neonatal records within the BC Perinatal Data Registry (BCDPR), for deliveries that were discharged between January 1, 2015 and March 31, 2018. The main outcome measures were alcohol use identified as a risk factor during pregnancy, associated maternal characteristics, pregnancy complications, and adverse neonatal outcomes. Estimates for the period and fiscal year prevalence were calculated. Chi-square tests were used to compare adverse neonatal outcomes and pregnancy complications by alcohol use during pregnancy. Logistic regression was used to examine the association between alcohol use during pregnancy and adverse neonatal outcomes and pregnancy complications, after adjusting for identified risk factors.ResultsA total of 144,779 linked records within the BCDPR were examined. The period prevalence of alcohol use during pregnancy identified as a risk factor was estimated to be 1.1% and yearly prevalence was 1.1%, 1.1%, 1.3% and 0.9% from the 2014/2015 fiscal year to 2017/2018, respectively. Indicated alcohol use was associated with younger maternal age, fewer antenatal visits, being nulliparous, a history of mental illness, substance use and smoking. Alcohol-exposed neonates had greater odds of being diagnosed with low birth weight (aOR = 1.25; 95% CI: 1.01, 1.53), other respiration distress of newborn (aOR = 2.57; 95% CI: 1.52, 4.07), neonatal difficulty in breastfeeding (aOR = 1.97; 95% CI: 1.27, 2.92) and unspecified feeding problems (aOR = 2.06; 95% CI: 1.31, 3.09)ConclusionsThe prevalence of alcohol use during pregnancy identified as a risk factor, estimated in this study, was comparable to the previous estimates within BCDPR. Prenatal alcohol exposure was associated with notable differences in maternal and neonatal characteristics and adverse neonatal outcomes. More consistent and thorough screening and prevention efforts targeting alcohol use in pregnancy are urgently needed in Canada.


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