In coming years, as the nursing shortage increases, nurses and other healthcare professionals will experience increasing stress in the workplace. The impact of workplace stress is significant for nurses as well as their employers. It is imperative nurses be supported in a healthy work environment that fosters resilience and reduces the impact of stress. This article will provide a review of workplace stress and the harmful effect it can have on nurses. It will also outline the importance of resilience and promoting nurse resilience through the creation of a workplace environment that has a foundation in caring.