An experiment was conducted to study the effect of <em>Zataria multifora</em> (ZM) on the performance and liver histopathology of broiler chickens contaminated with aflatoxin B1 (AFB1). One hundred and sixty Ross 308 male broilers (one-day-old) were divided into four treatment groups with four replicates with 10 birds in each replicate. The chickens were reared on the floor for 35 days. The groups were contaminated with AFB1 at two different concentrations,<em> i.e.,</em> 0 and 1000 ppb, and fed ZM in their feed at the concentrations of 0 and 20 gr Kg 1. The evaluated performance parameters were subjected to a completely randomized design with a 2×2 factorial arrangement of the treatments using SAS software (version 9/1). AFB1 had a statistical lowering effects on the feed intake, body weight, body weight gain and average weight of the carcass, thigh, chest, bursa of fabricius, back and neck. Also, the weights of liver, gizzard, pancreas, proventriculus, abdominal fat, full intestine, and heart were increased with AFB1 (P<0.05). In histopathological evaluations, the liver of chickens that received feed containing AFB1 showed multifocal and varied cytoplasmic vacuolization, severe fatty change, degenerating foci, fibrosis of the portal regions, and bile duct hyperplasia. The variables that were evaluated in this study showed that ZM had significant efficacy in diminishing the aflatoxins negative effects on the chickens.
Effects of licorice extract, probiotic, toxin binder and poultry litter biochar on performance, immune function, blood indices and liver histopathology of broilers exposed to aflatoxin-B1
