Genetic predisposition for high stress reactivity amplifies effects of early-life adversity

2016 ◽  
Vol 70 ◽  
pp. 85-97 ◽  
Author(s):  
Silja McIlwrick ◽  
Alexandra Rechenberg ◽  
Mariana Matthes ◽  
Jessica Burgstaller ◽  
Thomas Schwarzbauer ◽  
...  
Addiction ◽  
2018 ◽  
Vol 114 (5) ◽  
pp. 798-806 ◽  
Author(s):  
William R. Lovallo ◽  
Andrew J. Cohoon ◽  
Ashley Acheson ◽  
Kristen H. Sorocco ◽  
Andrea S. Vincent

2019 ◽  
Vol 43 (7) ◽  
pp. 1519-1527 ◽  
Author(s):  
William R. Lovallo ◽  
Andrew J. Cohoon ◽  
Kristen H. Sorocco ◽  
Andrea S. Vincent ◽  
Ashley Acheson ◽  
...  

2015 ◽  
Vol 41 (7) ◽  
pp. 1724-1732 ◽  
Author(s):  
William R Lovallo ◽  
Mary-Anne Enoch ◽  
Ashley Acheson ◽  
Andrew J Cohoon ◽  
Kristen H Sorocco ◽  
...  

Medicine ◽  
2016 ◽  
Vol 95 (39) ◽  
pp. e4745 ◽  
Author(s):  
Rosan Luijcks ◽  
Catherine J. Vossen ◽  
Suzanne Roggeveen ◽  
Jim van Os ◽  
Hermie J. Hermens ◽  
...  

2019 ◽  
Vol 6 (3) ◽  
pp. 1 ◽  
Author(s):  
Mary Tarsha ◽  
Darcia Narvaez

Although most people want children to thrive, many adults in industrialized nations have forgotten what that means and how to foster thriving. We review the nature and effects of the evolved developmental system for human offspring, a partnership system that fosters every kind of wellbeing. The environment and the type of care received, particularly in early life, shape neurobiological process that give rise to social and moral capacities. A deep view of history sheds light on converging evidence from the fields of neuroscience, developmental psychology, epigenetics, and ethnographic research that depicts how sociomoral capacities are not hardwired but are biosocially constructed. The Evolved Nest is the ecological system of care that potentiates both physical and psychological thriving, the foundations of cooperative and egalitarian societies. Deprivation of the evolved nest thwarts human development, resulting in sub-optimal, species-atypical outcomes of illbeing, high stress reactivity, dysregulation, and limited sociomoral capabilities. Utilizing a wider lens that incorporates humanity’s deep ancestral history, it becomes clear that deprivation of the evolved nest cuts against the development of human nature and humanity’s cultural heritage. Returning to providing the evolved nest to families and communities holds the potential to revise contemporary understandings of wellbeing and human nature. It can expand current metrics of wellness, beyond resilience to optimization.


2020 ◽  
Vol 119 ◽  
pp. 104954
Author(s):  
Ulrike U. Bentele ◽  
Maria Meier ◽  
Eva Unternaehrer ◽  
Stephanie J. Dimitroff ◽  
Annika B.E. Benz ◽  
...  

2019 ◽  
Author(s):  
Mary Elizabeth Zinn ◽  
Edward Huntley ◽  
Daniel Keating

Introduction. Early life adversity (ELA) can result in negative health-outcomes, including psychopathology. Evidence suggests that adolescence is a critical developmental period for processing ELA. Identity formation, which is crucial to this developmental period, may moderate the effect between ELA and psychopathology. One potential moderating variable associated with identity formation is Prospective Self, a latent construct comprised of future-oriented attitudes and behaviors.Methods. Participants are from the first wave of an ongoing longitudinal study designed to characterize behavioral and cognitive correlates of risk behavior trajectories. A community sample of 10th and 12th grade adolescents (N = 2017, 55% female) were recruited from nine public school districts across eight Southeastern Michigan counties in the United States. Data were collected in schools during school hours or after school via self-report, computer-administered surveys. Structural equation modeling was used in the present study to assess Prospective Self as a latent construct and to evaluate the relationship between ELA, psychopathology, and Prospective Self.Results. Preliminary findings indicated a satisfactory fit for the construct Prospective Self. The predicted negative associations between Prospective Self and psychopathology were found and evidence of moderation was observed for externalizing behavior problems, such that the effects of ELA were lower for individuals with higher levels of Prospective Self. Conclusion. These results support the role of Prospective Self in conferring resilience against externalizing behavior problems associated with ELA among adolescents. Keywords: Adolescence, Adverse Childhood Experiences, Psychopathology, Self-concept, Adolescent Health, Early Life Adversity


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