Maternal anaemia and risk of adverse obstetric and neonatal outcomes in South Asian countries: A systematic review and meta-analysis

South Asian countries report the highest prevalence of common mental disorders (CMDs) globally. This systematic review and meta-analysis report the pooled prevalence of CMDs among the South Asian countries. Database searches were conducted in eight electronic databases. Titles, abstracts, full-text screening, and extraction of data on the event rate of 17 indicators of CMDs were performed by two independent reviewers. A total of 160 studies were included and data analysis was done using the Comprehensive Meta-analysis Software (v.3). A prevalence of depressive symptoms was 26.4% among 173,449 participants, alcohol abuse was 12.9% (n = 107,893); anxiety 25.8% (n = 70,058); tobacco smoking 18.6% (n = 84,965); PTSD 17.2% (n = 42,298); mixed anxiety and depression 28.4% (n = 11,102); suicidal behaviors 6.4% (n = 25,043); misuse of opiates 0.8% (n = 37,304); tobacco chewing 21.0% (n = 10,586); use of cannabis 3.4% (n = 10,977); GAD 2.9% (n = 70,058); bipolar disorder 0.6% (n = 7,197); IV drug abuse 2.5% (n = 15,049); panic disorder 0.01% (n = 28,087); stimulant use 0.9% (n = 1,414); OCD 1.6% (n = 8,784) and phobic disorders 1.8% (n = 27,754). This study reported a high prevalence of CMDs in South Asian countries; necessitating further research on psychiatric epidemiology in those contexts. It informs the need for effective policymaking and implementation of culturally appropriate multilevel interventions.

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Adolescent Childbearing Age and Risk of Adverse Perinatal and Health Outcomes in South Asian Countries: A Systematic Review and Meta-Analysis

Journal of Womens Health Issues and Care ◽

10.4172/2325-9795.1000298 ◽

2018 ◽

Vol 07 (01) ◽

Cited By ~ 1

Author(s):

Md Rashed Alam ◽

Md Nuruzzaman Khan ◽

Md Mizanur Rahman ◽

Tapan Kumar Roy

Keyword(s):

Systematic Review ◽

Health Outcomes ◽

South Asian ◽

Meta Analysis ◽

Asian Countries ◽

Childbearing Age ◽

Adolescent Childbearing

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Prevalence of antenatal depression in South Asia: a systematic review and meta-analysis

European Journal of Public Health ◽

10.1093/eurpub/ckaa165.557 ◽

2020 ◽

Vol 30 (Supplement_5) ◽

Author(s):

R Mahendran ◽

S Puthussery ◽

M Amalan

Keyword(s):

Systematic Review ◽

Sri Lanka ◽

Pregnant Women ◽

South Asia ◽

South Asian ◽

Meta Analysis ◽

Antenatal Depression ◽

Diagnosis And Treatment ◽

Asian Countries ◽

Pooled Prevalence

Abstract Background Antenatal depression carries significant adverse implications for the health and well-being of women, babies and their families. While prevalence of perinatal mental disorders in low-and lower-middle-income countries tends to be higher compared to high-income countries, rates tend to vary widely among countries in certain regions such as South Asia. This study estimated the pooled prevalence of antenatal depression in South Asia and examined variations in individual countries. Methods We conducted a systematic review and meta-analysis. A comprehensive search was conducted on thirteen electronic databases and grey sources for articles published between 1·1·2007 and 31·5·2018 from South Asian countries including Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka. Studies reporting quantitative prevalence estimates of antenatal depression using a validated diagnostic/ screening tool identified, screened and appraised using a two-stage process. A meta-analysis was conducted using the proportion (%) of pregnant women identified as having antenatal depression as the primary outcome. Results Thirty-three studies involving 13,087 pregnant women were included in the meta-analysis. Overall pooled prevalence was 24·57% (95% CI: 19·34, 30·69). Prevalence rates for India (17·74%, 95% CI: 11·19, 26·96) and Sri Lanka (15·87%, 95% CI: 14·04, 17·88) were lower compared to the overall prevalence whereas the rates for Pakistan (32·2%, 95% CI: 23·11, 42·87) and Nepal (50%, 95% CI: 35·64,64·36) were higher. Conclusions While robust prevalence studies are sparse in most South Asian countries, one in four pregnant women is likely to experience antenatal depression in the region. The issue needs to be recognised in health policy and practice for resource allocation and capacity building at regional and national levels for prevention, diagnosis and treatment. Key messages One in four pregnant women is likely to experience antenatal depression in South Asia region. Targeted efforts are needed at national and regional levels for prevention, diagnosis and treatment.

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High prevalence of vitamin D insufficiency among South Asian pregnant women: A systematic review and meta-analysis

British Journal Of Nutrition ◽

10.1017/s0007114521004360 ◽

2021 ◽

pp. 1-32

Author(s):

Mahbubul H Siddiqee ◽

Badhan Bhattacharjee ◽

Umme Ruman Siddiqee ◽

Mohammad Meshbhaur Rahman

Keyword(s):

Systematic Review ◽

Vitamin D ◽

Pregnant Women ◽

South Asian ◽

Meta Analysis ◽

Vitamin D Insufficiency ◽

Mitigation Strategies ◽

Significant Heterogeneity ◽

Asian Countries ◽

Pooled Prevalence

Abstract Insufficiency of vitamin D, during pregnancy, is a common cause of various pregnancy-related complications. Despite such insufficiency being frequently reported among South Asian pregnant women, the absence of systematic review and meta-analysis renders the true extent of this problem poorly characterized. In this systematic review, three main databases (PubMed, Scopus, and Google Scholar) were searched for original studies. We included original studies published between 1st January 2001 to 31st December 2019, conducted on pregnant women who lived in South Asian countries and reported the prevalence of vitamin D insufficiency among the study participants. Twenty studies with a total of 7,804 participants from four South Asian countries finally met our selection criteria. Overall pooled prevalence of insufficiency was 65% [95 % CI: 51% to 78%] with a significant heterogeneity (I2 = 99.37 %; p = 0.00). The average level of vitamin D ranged from 9 ng/mL to 24.86 ng/mL with a weighted mean of 16.37 ng/mL (weighted standard deviation 7.13 ng/mL). The highest prevalence of insufficiency was found in Pakistan (76%) followed by India (67%), Bangladesh (64%), and Nepal (14%). Results obtained in this study suggest that vitamin D insufficiency is highly prevalent among South Asian pregnant women. Being the first systematic review in this region, findings from this study will help in future studies and strengthen the evidence for policymakers to develop effective mitigation strategies.

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High burden of hypovitaminosis D among the children and adolescents in South Asia: A systematic review and meta-analysis

10.21203/rs.3.rs-747227/v1 ◽

2021 ◽

Author(s):

Mahbubul Hasan Siddiqee ◽

Badhan Bhattacharjee ◽

Umme Ruman Siddiqi ◽

Mohammad Meshbahur Rahman

Keyword(s):

Systematic Review ◽

Vitamin D ◽

Children And Adolescents ◽

South Asian ◽

Meta Analysis ◽

Hypovitaminosis D ◽

Health Concern ◽

Asian Countries ◽

The South ◽

Asian Children

Abstract Background: Vitamin D is vital for the growth and development of children. While deficiency and/or insufficiency of vitamin D among South Asian children are frequently reported in the literature, the lack of a meta-analysis has left its true extent poorly characterized. In this study, we aimed to conduct a systematic review and perform meta-analyses of the prevalence of hypovitaminosis D among the children of the South Asian countries.Methods: Two major electronic search engines (PubMed and Scopus) and one database (Google scholar) were used; original studies, conducted among South Asian children and adolescents and published between 1st January 2001 and 31st December 2019. A random-effect meta-analysis was also performed to calculate the pooled prevalence of hypovitaminosis D followed by subgroup analyses for countries and age-groups.Results: After applying inclusion and exclusion criteria, a total of 41 studies with a total population size of 18,233 were finally selected. The overall prevalence of hypovitaminosis D was 61% [95% CI: 46% to 71%] with highly significant heterogeneity (I2 = 99.72%; p = 0.00). The average level of serum vitamin D ranged from 5 ng/mL to 34 ng/mL, with a weighted mean of 19.15 ng/mL (weighted standard deviation 11.59 ng/mL). Country-wise analysis showed that hypovitaminosis D in Afghanistan was the highest [96.2%; 95% CI: 91% to 99%], followed by Pakistan [94%; 95% CI: 90% to 96%], India [64%; 95% CI: 46% to 79%], Bangladesh [35.48%; 95% CI: 32% to 39%], Nepal [35%; 95% CI: 1% to 83%.]and Sri Lanka [25%; 95% CI: 16% to 36%]. Age-group analyses revealed that hypovitaminosis D was most prevalent among neonates [85%; 95% CI: 76% to 91%], followed by school-going children [57%; 95% CI: 33% to 80%], and pre-school children [55%; 95% CI: 35% to 75%].Conclusion: This study generates quantitative evidence and specific extent of hypovitaminosis D in the South Asian countries as a public health concern. Being the first systematic review for this region, results from this study will create awareness and will facilitate adopting mitigation strategies by the policymakers and the governments to address this problem.

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