Variation of long-lived free radicals responsible for the EPR native signal in bone of aged or diseased human females and ovariectomized adult rats

2005 ◽  
Vol 39 (3) ◽  
pp. 255-262 ◽  
Author(s):  
G.H. Kenner ◽  
A.B. Brik ◽  
G. Liu ◽  
E.H. Haskell ◽  
R.B. Hayes ◽  
...  
Keyword(s):  
Free Radicals ◽  
Adult Rats ◽  
Human Females ◽  
Ovariectomized Adult Rats

METABOLISM OF 20β-HYDROXY-4-PREGNEN-3-ONE IN UTERINE TISSUE OF NON-PREGNANT RATS IN VITRO

1976 ◽  
Vol 83 (3) ◽  
pp. 604-620 ◽  
Author(s):  
B. P. Lisboa ◽  
M. Holtermann
Keyword(s):  
Biological Activity ◽  
Adult Female ◽  
Female Rats ◽  
Uterine Tissue ◽  
Rat Uterus ◽  
Adult Rats ◽  
Pregnant Rats ◽  
Progesterone Metabolites ◽  
Ovariectomized Adult Rats

ABSTRACT In vitro experiments carried out with uterus preparations of ovariectomized adult rats indicate the presence in this tissue of a 20β-hydroxysteroid-oxidoreductase which catalyzes the conversion of 20β-hydroxy-4-pregnen-3-one to progesterone. Since a hepatic 20β-hydroxysteroid-oxidoreductase is absent in adult female rats, the myometrial enzyme can be responsible for the biological activity of 20β-hydroxy-4-pregnen-3-one in these animals. Besides progesterone five metabolites were isolated and identified after incubation of [4-14C]20β-hydroxy-4-pregnen-3-one with uterine tissue: 20β-hydroxy-5α-pregnan-3-one, 20β-hydroxy-5β-pregnan-3-one, 5α-pregnane-3α,20β-diol, 4-pregnene-3α,20β-diol and 4-pregnene-3β,20β-diol. The conversion of 20β-hydroxy-4-pregnen-3-one to progesterone permits us to regard all five steroids isolated as progesterone metabolites in the rat uterus. 20β-hydroxy-5β-pregnan-3-one is the first C21-metabolite with a 5β(H)-configuration isolated in the rat uterus, which indicates the presence of 5β-reductase in this tissue.

Dose Effects of Propranolol on Cancellous and Cortical Bone in Ovariectomized Adult Rats

2006 ◽  
Vol 318 (3) ◽  
pp. 1118-1127 ◽  
Author(s):  
N. Bonnet ◽  
N. Laroche ◽  
L. Vico ◽  
E. Dolleans ◽  
C. L. Benhamou ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Adult Rats ◽  
Dose Effects ◽  
Ovariectomized Adult Rats

Effect of Median Eminence Lesions and Hormonal Replacement on the Prolactin Receptors in the Adrenal Gland and Langerhans Islets from Ovariectomized Adult Rats

1985 ◽  
Vol 5 (1) ◽  
pp. 105-119 ◽  
Author(s):  
Isabel A. Lüthy ◽  
Marta Tesone ◽  
Ricardo M. Oliveira-filho ◽  
Gustavo M. Somoza ◽  
Eduardo H. Charreau ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Median Eminence ◽  
Prolactin Receptors ◽  
Adult Rats ◽  
Hormonal Replacement ◽  
Langerhans Islets ◽  
Ovariectomized Adult Rats

THE EFFECT OF GONADOTROPHIC HORMONES ON THE HYPOPHYSIS OF THE RAT

1962 ◽  
Vol 41 (1) ◽  
pp. 31-34 ◽  
Author(s):  
F. E. Szontágh ◽  
S. Uhlarik ◽  
A. Jakobovits
Keyword(s):  
Anterior Lobe ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Moderate Increase ◽  
Adult Rats ◽  
Ovariectomized Adult Rats

ABSTRACT The weight of the hypophysis and the ratio of the PAS-positive to PAS-negative cells in the anterior lobe of intact and ovariectomized adult rats increased significantly following treatment with serum gonadotrophin (PMS). After the administration of human chorionic gonadotrophin (HCG) a slight decrease of the hypophyseal weight and a moderate increase of the number of PAS-positive cells was observed in both intact and spayed groups of animals. Both gonadotrophic substances failed to inhibit the appearance of castration cells in the hypophysis.

Synaptic Profile and Density in Hippocampus in the Ovariectomized Adult Rats Taking Estrogen, Progestogen and Tamoxifen

1999 ◽  
Vol 6 (4) ◽  
pp. 351
Author(s):  
I Silva ◽  
E C Baracat ◽  
M A Haidar ◽  
E Haapalainen ◽  
L E.A.M Mello ◽  
...  
Keyword(s):  
Adult Rats ◽  
Ovariectomized Adult Rats

Effect of 17ß-estradiol on zinc content of hippocampal mossy fibers in ovariectomized adult rats

BioMetals ◽  
2012 ◽  
Vol 25 (6) ◽  
pp. 1129-1139 ◽  
Author(s):  
E. Padilla-Gómez ◽  
V. Beltrán-Campos ◽  
S. Montes ◽  
A. Díaz-Ruíz ◽  
G. L. Quirarte ◽  
...  
Keyword(s):  
Zinc Content ◽  
Mossy Fibers ◽  
Adult Rats ◽  
Ovariectomized Adult Rats
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