Effect of post-irradiation thermal treatments on the stability of gamma-irradiated glass dosimeter

2007 ◽  
Vol 76 (8-9) ◽  
pp. 1523-1526 ◽  
Author(s):  
K. Farah ◽  
A. Kovács ◽  
A. Mejri ◽  
H. Ben Ouada
2013 ◽  
Vol 33 (9) ◽  
pp. 823-828 ◽  
Author(s):  
Carmina Menchaca-Campos ◽  
Gonzalo Martínez-Barrera ◽  
Héctor López-Valdivia ◽  
Héctor Carrasco ◽  
Alberto Álvarez-Castillo

Abstract Post-irradiation effects on nylon 6,12 crystalline fibers gamma-irradiated 6 years previously (6YI) were studied, including thermal stability and morphology; their relationship with storage time was also studied. The results of these studies were compared with those obtained for non-irradiated (NI) and namely freshly irradiated (FI) crystalline fibers. The results include analyses like thermogravimetric analysis (TGA), differential thermal analysis (DTA), scanning electron microscopy (SEM) and optical images for (6YI and FI) both kinds of nylon 6,12 fibers. The results showed that the most prominent effect is related to the reaction progress. The chain scission and/or crosslinking mechanisms, as well as the free radicals, allow proceeding with the reaction, and consequently, changes on the properties of the FI samples. The melting point, degree of crystallinity, degradation temperature and morphology prove that additional chemical reactions and surface modifications keep occurring in the fibers long after the irradiation process has ended. With storage time, the surface becomes rougher, the color turns yellowish, the melting point diminishes and the degree of crystallinity increases.


2008 ◽  
Vol 43 (7) ◽  
pp. 1315-1318 ◽  
Author(s):  
Anan M. Al-Karmi ◽  
M.A. Morsy

Author(s):  
Eloise Williams ◽  
Nicole Isles ◽  
Brian Chong ◽  
Katherine Bond ◽  
Yano Yoga ◽  
...  

Saliva has recently been proposed as a suitable specimen for the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Use of saliva as a diagnostic specimen may present opportunities for SARS-CoV-2 reverse transcription polymerase chain reaction (RT-PCR) testing in remote and low-resource settings. Determining the stability of SARS-CoV-2 RNA in saliva over time is an important step in determining optimal storage and transport times. We undertook an in vitro study to assess whether SARS-CoV-2 could be detected in contrived saliva samples. The contrived saliva samples comprised 10 ml pooled saliva spiked with gamma-irradiated SARS-CoV-2 to achieve a concentration of 2.58×104 copies ml SARS-CoV-2, which was subsequently divided into 2 ml aliquots comprising: (i) neat saliva; and a 1 : 1 dilution with (ii) normal saline; (iii) viral transport media, and (iv) liquid Amies medium. Contrived samples were made in quadruplicate, with two samples of each stored at either: (i) room temperature or (ii) 4 °C. SARS-CoV-2 was detected in all SARS-CoV-2 spiked samples at time point 0, day 1, 3 and 7 at both storage temperatures using the N gene RT-PCR assay and time point 0, day 1 and day 7 using the Xpert Xpress SARS-CoV-2 (Cepheid, Sunnyvale, USA) RT-PCR assay. The ability to detect SARS-CoV-2 in saliva over a 1 week period is an important finding that presents further opportunities for saliva testing as a diagnostic specimen for the diagnosis of SARS-CoV-2.


HortScience ◽  
1996 ◽  
Vol 31 (4) ◽  
pp. 644f-644
Author(s):  
Durward Smith ◽  
Joseph D. Norton

Chinese chestnuts (Castanea molissima Blume) are a highly perishable commodity which requires artificial storage means and is easily spoiled by fungi. This investigation was designed to develop processes and adapt equipment for more efficient processing and storage of Chinese chestnuts, establish parameters for optimum fresh storage, and to compare the yields and qualities of the chestnuts processed by the test methods. Chinese chestnuts were prepared for fresh storage by vacuum infusing mycostatic solutions and modified starch coatings inside the shells. Vacuum treatment facilitated perfect contact of these solutions with the surfaces of the kernels, and was a more rapid method than atmospheric or pressure soaking methods. Vacuum infused pretreatments limited desiccation, minimized spoilage, reduced storage weight losses, and yielded products with better color and texture than conventional storage. Thermal treatments for surface pasteurization were defined. A storage relative humidity of 87% was found to be optimal.


1999 ◽  
Vol 6 (2) ◽  
pp. 121-126
Author(s):  
Renada D. Henderson ◽  
Timothy D. Henderson ◽  
Henry J. Irving ◽  
John R. J. Sorenson

Dicopper(II) tetrakis(3,5-diisopropylsalicylate), [Cu(II)2(3,5-DIPS)4], is effective in increasing survival of lethally irradiated mice when it is administered after irradiation. The possibility that this radiorecovery activity might also facilitate recovery from radiation-induced impaired increase in body mass and locomotion was examined. Cu(II)2(3,5-DIPS)4 was used to treat LD50/30 gamma irradiated female C57BL/6 mice after irradiation. A dose of 0, 5, 10, or 20 μmol Cu(II)2  (3,5-DIPS)4 /kilogram of body mass was administered subcutaneously 3 hrs after LD50/30 irradiation and change in body mass and locomotor activity measured daily throughout the 30 day post-irradiation period. Treatment with 5, 10, or 20 μmolCu(II)2(3,5-DIPS)4 /kg of body mass increased survival, which was statistically significant for the 10 μmol /kg of body mass-treated group compared to the vehicle-treated group (P<0.05) , significantly (P<0.05) increased recovery of locomotion from days 13 to 15 post-irradiation onward for all treated groups compared to vehicle-treated mice, and increased recovery of body mass gain from day 14 onward for the 20 μmol /kg of body mass-treated group (P<0.001) and day 21, although not statistically significant, for the 10 μmol /kg of body mass-treated group. There were no statistically significant differences between the increase in survival, recovered increase in body mass, and recovered increase in locomotion for mice treated with 10 μmol or 20 μmolCu(II)2(3,5-DIPS)4 /kg on day 30 post-irradiation. It is concluded that Cu(II)2(3,5-DIPS)4 in addition to increasing survival of irradiated mice increases the rate of recovery of radiation-induced decrease in body mass and locomotion.


1984 ◽  
Vol 10 (9) ◽  
pp. 1555-1559 ◽  
Author(s):  
Thomas W Menard ◽  
Kenneth T Izutsu ◽  
W.Y Ensign ◽  
Patricia J Keller ◽  
Thomas H Morton ◽  
...  

1997 ◽  
Vol 17 (1) ◽  
pp. 355-363 ◽  
Author(s):  
C G Maki ◽  
P M Howley

Levels of the tumor suppressor protein p53 are normally quite low due in part to its short half-life. p53 levels increase in cells exposed to DNA-damaging agents, such as radiation, and this increase is thought to be responsible for the radiation-induced G1 cell cycle arrest or delay. The mechanisms by which radiation causes an increase in p53 are currently unknown. The purpose of this study was to compare the effects of gamma and UV radiation on the stability and ubiquitination of p53 in vivo. Ubiquitin-p53 conjugates could be detected in nonirradiated and gamma-irradiated cells but not in cells which were UV treated, despite the fact that both treatments resulted in the stabilization of the p53 protein. These results demonstrate that UV and gamma radiation have different effects on ubiquitinated p53 and suggest that the UV-induced stabilization of p53 results from a loss of p53 ubiquitination. Ubiquitinated forms of p21, an inhibitor of cyclin-dependent kinases, were detected in vivo, demonstrating that p21 is also a target for degradation by the ubiquitin-dependent proteolytic pathway. However, UV and gamma radiation had no effect on the stability or in vivo ubiquitination of p21, indicating that the radiation effects on p53 are specific.


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