Risk factors for Toxoplasma gondii infection among pregnant women: Result of a cross-sectional study in Morocco

2009 ◽  
Vol 57 ◽  
pp. S36 ◽  
Author(s):  
M. Laboudi ◽  
B. El Mansouri ◽  
F. Sebti ◽  
Y. Coppieters ◽  
M. Rhajaoui
Keyword(s):  
Risk Factors ◽  
Toxoplasma Gondii ◽  
Pregnant Women ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Toxoplasma Gondii Infection

scholarly journals Seroprevalence and Risk Factors of Toxoplasma gondii Infection among Pregnant Women in Kumasi: A Cross-Sectional Study at a District-Level Hospital, Ghana

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Bhavana Singh ◽  
Linda Batsa Debrah ◽  
Godfred Acheampong ◽  
Alexander Yaw Debrah
Keyword(s):  
Risk Factors ◽  
Secondary Education ◽  
Toxoplasma Gondii ◽  
Pregnant Women ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Elisa Technique ◽  
Toxoplasma Gondii Infection ◽  
Level Hospital

Background. This study investigated the prevalence and risk factors of Toxoplasma gondii infection among pregnant women in a district-level hospital in Ghana and compared the diagnostic performance of the rapid diagnostic test (RDT) and enzyme-linked immunosorbent assay (ELISA) for T. gondii diagnosis. Method. This cross-sectional study included 400 consecutive consenting women in their first-trimester stage of pregnancy. A validated well-structured closed-ended questionnaire was used to collect sociodemographic data and possible risk factors of each participant. Blood samples were collected for analysis of T. gondii IgG and IgM using the commercial ELISA Kit and RDT. Results. Seroprevalence of toxoplasmosis was 21.5% and 57.3% based on the RDT and ELISA technique, respectively. Secondary education ( cOR = 1.9 , 95% CI (1.1-3.1), and p = 0.020 ) and contact with cats ( cOR = 1.7 , 95% CI (1.1-2.8), and p = 0.030 ) were significant predictors of T. gondii infection, with the former being the only independent risk factor for T. gondii infection ( aOR = 1.8 , 95% CI (1.0-3.0), and p = 0.034 ) by the ELISA method. The sensitivity, specificity, and area under the curve (AUC) of RDT-IgM against ELISA were 42.9%, 95.9%, and 0.694, respectively, whereas those of RDT-IgG were 31.0%, 91.2%, and 0.611, respectively. The diagnostic consistency between the two methods was fair for both RDT-IgM ( κ = 0.304 ) and RDT-IgG ( κ = 0.201 ). Conclusion. The prevalence of T. gondii infection among pregnant women at Kumasi is 21.5% and 57.3% based on the RDT and ELISA technique, respectively. Secondary education and contact with cats were the major risk factors of T. gondii infection. Using ELISA as the reference, the RDT used in this study for the diagnosis of T. gondii infection has low sensitivity, and therefore, it is unreliable. However, this finding does not invalidate all RDTs because there are several other brands of RDT with good sensitivity and specificity. Further studies to ascertain the performance of other commercially available RDT kits are needed.

scholarly journals Toxoplasma gondii infection in pregnant women: a cross-sectional study in Matehuala City, Mexico

BMJ Open ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. e033995
Author(s):  
Ada-Agustina Sandoval-Carrillo ◽  
Angel Antonio Vértiz-Hernández ◽  
Jose-Manuel Salas-Pacheco ◽  
Olga Edith González-Lugo ◽  
Elizabeth-Irasema Antuna-Salcido ◽  
...  
Keyword(s):  
Risk Factors ◽  
Toxoplasma Gondii ◽  
Pregnant Women ◽  
Protective Factor ◽  
Cross Sectional Study ◽  
Secondary Outcome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Infection Age ◽  
Igm Antibodies

ObjectivesThis study aimed to determine the seroprevalence of Toxoplasma gondii (T. gondii) infection in pregnant women in Matehuala City, Mexico; and the associated risk factors.DesignA cross-sectional study.SettingMatehuala City, Mexico.Participants311 pregnant women.Primary and secondary outcome measuresSera of women were analysed for anti-T. gondii IgG and IgM antibodies by commercially available immunoassays. Bivariate and multivariate analyses were used to assess the association between T. gondii seroprevalence and the characteristics of the pregnant women.ResultsThirteen (4.2%) of the 311 pregnant women studied were positive for anti-T. gondii IgG antibodies. No anti-T. gondii IgM antibodies were found in anti-T. gondii IgG seropositive women. No association between seropositivity and history of blood transfusion, transplantation, caesarean sections, deliveries, miscarriages or number of pregnancies was found. Logistic regression analysis of sociodemographic, behavioural and housing variables showed that availability of potable water at street represented a risk factor for T. gondii infection (age-adjusted OR=2.18; 95% CI: 1.05 to 4.53; p=0.03), whereas being born in Mexico was a protective factor for infection (age-adjusted OR=0.01; 95% CI: 0.001 to 0.35; p=0.008).ConclusionsIn this first study on the seroepidemiology of T. gondii infection in pregnant women in Matehuala, we conclude that the seroprevalence of T. gondii infection is low and similar to those reported in pregnant women in other Mexican cities. However, the seroprevalence found is lower than those reported in pregnant women in other countries in the Americas and Europe. Two risk factors associated with T. gondii infection were identified. Results of the present study may help for the optimal planning of preventive measures against toxoplasmosis in pregnant women.

Some risk factors for reproductive failures and contribution of Toxoplasma gondii infection in sheep and goats of Central Ethiopia: A cross-sectional study

2013 ◽  
Vol 95 (3) ◽  
pp. 894-900 ◽  
Author(s):  
Endrias Zewdu Gebremedhin ◽  
Abebe Agonafir ◽  
Tesfaye Sisay Tessema ◽  
Getachew Tilahun ◽  
Girmay Medhin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Toxoplasma Gondii ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Central Ethiopia ◽  
Sheep And Goats ◽  
Toxoplasma Gondii Infection

Seroepidemiological map of Toxoplasma gondii infection and associated risk factors in preconception period in China: A nationwide cross-sectional study

2018 ◽  
Vol 44 (6) ◽  
pp. 1134-1139 ◽  
Author(s):  
Qiongjie Zhou ◽  
Qiaomei Wang ◽  
Haiping Shen ◽  
Yiping Zhang ◽  
Shikun Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Toxoplasma Gondii ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Toxoplasma Gondii Infection ◽  
Associated Risk Factors
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