scholarly journals Machine learning model predicts short-term mortality among prehospital patients: A prospective development study from Finland

2021 ◽  
Vol 5 ◽  
pp. 100089
Author(s):  
Joonas Tamminen ◽  
Antti Kallonen ◽  
Sanna Hoppu ◽  
Jari Kalliomäki
2017 ◽  
Author(s):  
Aymen A. Elfiky ◽  
Maximilian J. Pany ◽  
Ravi B. Parikh ◽  
Ziad Obermeyer

ABSTRACTBackgroundCancer patients who die soon after starting chemotherapy incur costs of treatment without benefits. Accurately predicting mortality risk from chemotherapy is important, but few patient data-driven tools exist. We sought to create and validate a machine learning model predicting mortality for patients starting new chemotherapy.MethodsWe obtained electronic health records for patients treated at a large cancer center (26,946 patients; 51,774 new regimens) over 2004-14, linked to Social Security data for date of death. The model was derived using 2004-11 data, and performance measured on non-overlapping 2012-14 data.Findings30-day mortality from chemotherapy start was 2.1%. Common cancers included breast (21.1%), colorectal (19.3%), and lung (18.0%). Model predictions were accurate for all patients (AUC 0.94). Predictions for patients starting palliative chemotherapy (46.6% of regimens), for whom prognosis is particularly important, remained highly accurate (AUC 0.92). To illustrate model discrimination, we ranked patients initiating palliative chemotherapy by model-predicted mortality risk, and calculated observed mortality by risk decile. 30-day mortality in the highest-risk decile was 22.6%; in the lowest-risk decile, no patients died. Predictions remained accurate across all primary cancers, stages, and chemotherapies—even for clinical trial regimens that first appeared in years after the model was trained (AUC 0.94). The model also performed well for prediction of 180-day mortality (AUC 0.87; mortality 74.8% in the highest risk decile vs. 0.2% in the lowest). Predictions were more accurate than data from randomized trials of individual chemotherapies, or SEER estimates.InterpretationA machine learning algorithm accurately predicted short-term mortality in patients starting chemotherapy using EHR data. Further research is necessary to determine generalizability and the feasibility of applying this algorithm in clinical settings.


2021 ◽  
Vol 28 (1) ◽  
pp. 22-30
Author(s):  
Hon Fung Chow

This paper proposes and discusses the viability of a short-term grid maximum demand forecasting model combining autoregressive integrated moving average with regressors (ARIMAX) and support vector regression (SVR). Grid demand forecasting is essential to generation unit scheduling, maintenance planning and system security. Traditionally, grid demand is forecasted using multivariate linear regression models with parameters adjusted to past data. A disadvantage of the linear regression model is that the parameters require regular adjustment, otherwise the prediction accuracy will deteriorate over time. With recent advances in the field of machine learning and lower computational costs, the usage of machine learning in the power industry becomes increasingly practicable. The proposed model is a machine learning model that combines ARIMAX and SVR to exploit their respective effectiveness in predicting linear and non-linear data. In contrast to linear regression models, the machine learning model automatically updates itself when new data is included. The hybrid model is benchmarked against other forecasting models and demonstrated a marked improvement in accuracy, achieving RMSE of 67.7MW and MAPE of 1.32% in a seven-day forecast.


In the stock market, it is important to have accurate prediction of future behavior of stock price..Because of the great chance of financial loss as well as scoring profits at the same time, it is mandatory to have a secure prediction of the values of the stocks. But when it comes to predicting the value of a stock in future we tend to follow stock market experts but as technology is progressing we may use these technologies rather than following human experts who may be biased many times. Stock price prediction has been interesting area for investors and researchers. This article proposes an approach towards prediction of stock price using machine learning model Long Short Term Memory. This is an ensemble learning method that has been an exceedingly successful model for predicting sequence of numbers and words. Long Short Term Memory is a machine learning model for prediction. This technique is used to forecast the future stock price of a specific stock by using historical data of the stock gathered from Yahoo! Finance.


2018 ◽  
Author(s):  
Steen Lysgaard ◽  
Paul C. Jennings ◽  
Jens Strabo Hummelshøj ◽  
Thomas Bligaard ◽  
Tejs Vegge

A machine learning model is used as a surrogate fitness evaluator in a genetic algorithm (GA) optimization of the atomic distribution of Pt-Au nanoparticles. The machine learning accelerated genetic algorithm (MLaGA) yields a 50-fold reduction of required energy calculations compared to a traditional GA.


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