Recurrence of a malignant solitary fibrous tumor of the pleura 17 years after primary tumor resection – A case report

Abstract Background Primary urethral cancer is exceedingly rare, resulting in a limitation in clinicians’ experience, and an accurate diagnosis is often delayed due to the non-specific clinical presentation. Here, we present this case report to show the treatment of a patient with primary urethral cancer. Our patient was diagnosed as having primary urethral cancer in the First Clinical Hospital of Yichang by cystoscopy and biopsy. Due to her age, poor physical tolerance, and economic condition, she refused radical operation. Since there is no definite guideline for the treatment process of primary urethral cancer in clinics, operation methods and postoperative adjuvant treatments vary in different hospitals, leading to diverse prognostic effects. Case presentation An 88-year-old Asian woman had difficulty in urinating for more than 6 months and the syndrome was aggravated for 1 month. She chose a relatively conservative treatment plan: primary tumor resection combined with bladder perfusion chemotherapy. Postoperative pathology revealed “urethra” high-grade urothelial carcinoma (sarcoma-like variants) with extensive necrosis. After treatment with intravesical chemotherapeutic drug (hydroxycamptothecin 40 mg), she was eventually released from our hospital in a stable condition. Postoperation follow-up was performed to observe to what extent this conservative treatment plan improved the quality of life and overall survival time of our patient. Conclusions She needed radical resection according to the actual situation. However, her age restricted her tolerance to general anesthesia; relatively conservative treatment options are available to ensure a high quality of life. The treatment of primary tumor resection combined with bladder perfusion chemotherapy is feasible. This case highlights the importance of the dissemination of new cases and optimizing primary urethral cancer diagnosis to obtain an effective treatment.

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Oligo-metastatic pancreatic cancer affecting pulmonary nodules twelve years after primary tumor resection: A case report

The Journal of the Japanese Association for Chest Surgery ◽

10.2995/jacsurg.34.661 ◽

2020 ◽

Vol 34 (6) ◽

pp. 661-665

Author(s):

Soichiro Kiya ◽

Daisuke Taniguchi ◽

Tomoshi Tsuchiya ◽

Kaori Ishida ◽

Junya Fukuoka ◽

...

Keyword(s):

Pancreatic Cancer ◽

Case Report ◽

Primary Tumor ◽

Tumor Resection ◽

Pulmonary Nodules ◽

Primary Tumor Resection ◽

Metastatic Pancreatic Cancer

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Solitary fibrous tumor of the pleura as a rare cause of severe hypoglycemia: Doege-Potter syndrome

Perspectives in Surgery ◽

10.33699/pis.2020.99.2.95-98 ◽

2020 ◽

Vol 99 (2) ◽

pp. 95-98

Keyword(s):

Case Report ◽

Growth Factor ◽

Solitary Fibrous Tumor ◽

Tumor Resection ◽

Insulin Like Growth Factor ◽

En Bloc ◽

Solitary Fibrous Tumors ◽

Factor Ii ◽

Fibrous Tumor ◽

Recurrent Hypoglycemia

Introduction: Doege-Potter syndrome is a rare syndrome characterized by hypo-insulinemic hypoglycemia. It is caused by excessive ectopic secretion of insulin-like growth factor II from a solitary fibrous tumors of intrapleural or extrapleural origin. Laboratory tests reveal low levels of C-peptide and insulin, on the contrary insulin-like growth factor II level is elevated, which is characteristic for Doege-Potter syndrome. Majority of solitary fibrous tumors present no symptomatology, recurrent hypoglycemia is relatively rare, but it may be the only clinical manifestation. The therapy is surgical, consisting of radical en-bloc tumor resection. Case report: Authors present a case report of a patient with recurrent hypoglycemia caused solely by solitary fibrous tumor. Hypoglycemia resolved immediately after surgical resection and there were no recurrences. Conclusion: Doege-Potter syndrome should be considered as the differential diagnosis in a patient with suspicion on thoracic malignancy if accompanied by features suggestive of hypoglycemia. Prolonged follow up is strongly advised because of the risk of disease recurrence, even in patients with benign solitary fibrous tumors of the pleura (SFTP).

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Primary tumor resection after nivolumab treatment for metastatic renal cell carcinoma: A case report

Annals of Oncology ◽

10.1093/annonc/mdz343.077 ◽

2019 ◽

Vol 30 ◽

pp. vi134 ◽

Cited By ~ 1

Author(s):

Tokiyoshi Tanegashima ◽

Shigehiro Tsukahara ◽

Takashi Ikenoue ◽

Satoshi Otsubo ◽

Shuji Hasehawa ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Case Report ◽

Cell Carcinoma ◽

Metastatic Renal Cell Carcinoma ◽

Primary Tumor ◽

Renal Cell ◽

Tumor Resection ◽

Primary Tumor Resection

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Intravascular large B-cell lymphoma involving pleural solitary fibrous tumor: A case report and literature review

Human Pathology Case Reports ◽

10.1016/j.ehpc.2021.200530 ◽

2021 ◽

Vol 25 ◽

pp. 200530

Author(s):

Amintas Samuel ◽

Laurent Elodie ◽

Gros Audrey ◽

Sesboue Come ◽

Merlio Jean-Philippe ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

B Cell ◽

Solitary Fibrous Tumor ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Large B Cell Lymphoma ◽

Fibrous Tumor ◽

Large B Cell

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Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report

Surgical Case Reports ◽

10.1186/s40792-021-01209-4 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Kozue Matsuishi ◽

Kojiro Eto ◽

Atsushi Morito ◽

Hirokazu Hamasaki ◽

Keisuke Morita ◽

...

Keyword(s):

Case Report ◽

Solitary Fibrous Tumor ◽

Distant Metastasis ◽

Curative Resection ◽

Lung Metastases ◽

Lung Resection ◽

Left Lung ◽

Metastatic Lesion ◽

Case Presentation ◽

Fibrous Tumor

Abstract Background Solitary fibrous tumor (SFT) is a relatively rare mesenchymal tumor that mainly affects adults. Its prognosis is good after curative resection, but distant recurrences after 10 years or longer have been reported. Recurrent SFT usually arises as a local lesion; distant metastasis is rarely reported. Here, we report lung metastases that recurred a decade after excising a retroperitoneal primary SFT. Case presentation A 44-year-old woman had an SFT resected from her right retroperitoneum at our hospital. Ten years later, at age 54, she underwent a lung resection after CT showed three suspected metastases in her left lung. All three were histologically diagnosed as lung metastases from the retroperitoneal SFT. However, whereas the primary SFT had 1–2 mitotic cells/10 high power fields (HPF), the metastatic lesion increased malignancy, at 50/10 HPF. Conclusion Patients who have had resected SFTs should be carefully followed up, as malignancy may change in distant metastasis, as in this case.

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